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16 Cards in this Set

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pyruvate carboxylase
acetyl CoA carboxylase
propionyl CoA carboxylase

function of each enzyme
biotin

pyruvate carboxylase (pyruvate --> oxaloacetate; for gluconeogenesis)

acetyl CoA carboxylase (acetyl-CoA --> malonyl-CoA; to make FA's)

propionyl CoA carboxylase (proprionyl-CoA --> methylmalonyl-CoA; to enter TCA cycle)
deficiency results in alopecia, bowel inflammation, and muscle pain
biotin
pyruvate dehydrogenase (PDH)
α-ketoglutarate dehydrogenase
transketolase
thiamine (B1)
thymidylate synthase
enzymes in purine synthesis
folate
deficiency results in homocystinemia with the risk of DVT and atherosclerosis
folate
homocysteine methyltransferase
methylmalonyl CoA mutase
cobalamin (B12)
aminotransferases (transaminases), e.g., AST and ALT
δ-aminolevulinat (ALA) synthase
pyridoxine (B6)
deficiency due to INH therapy for TB
pyridoxine (B6)
deficiency results in sideroblastic anemia
pyridoxine (B6)
deficiency results in cheilosis or stomatitis (cracking or scaling of lip borders and corners of the mouth)
pyridoxine (B6)
deficiency results in convulsion
pyridoxine (B6)
deficiency results in corneal neovascularization
riboflavin (B2)
deficiency results in cheilosis or stomatitis
riboflavin (B2)
deficiency results in magenta-colored tongue
riboflavin (B2)
prolyl and lysyl hydroxlases
dopamine hydroxylase
ascorbate (vitamin C)
fatty acid synthase
fatty acyl CoA synthetase
pyruvate dehydrogenase
α-ketoglutarate dehydrogenase
pantothenate