Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
11 Cards in this Set
- Front
- Back
|
TQ:
Chronic Primary Adrenal Insufficiency: Clinical manifestations Occurs with loss of ____% of gland |
90
|
|
|
TQ:
Chronic Primary Adrenal Insufficiency: Clinical manifestations Symptoms and Signs (Most specific) |
Weakness 99%
Hyperpigmentation of skin 98% (Sun exposed, pressure points) Weight loss 97% Anorexia, nausea, and vomiting 90% Hypotension (<110/70) 87% Pigmentation of mucous membranes (tongue) 82% Abdominal pain 34% Salt craving 22% |
|
|
TQ:
Chronic Primary Adrenal Insufficiency: Clinical manifestations Symptoms and Signs (Most specific) that are underlined |
Hyperpigmentation of skin
Hypotension Pigmentation of mucous membranes (tongue) |
|
|
TQ:
Laboratory findings |
Hyponatremia
Hyperkalemia Hypoglycemia |
|
|
TQ:
Acute Primary Adrenal Insufficiency Treatment |
Hydrocortisone intravenously, 100mg bolus, infusion 200mg over 24 hours
|
|
|
Acute Primary Adrenal Insufficiency:
How does is happen? |
Chronic insufficiency, but a big stressor causes APAI
|
|
|
TQ:
What is the following? Glucocorticoid production low (Results in hypoglycemia But Mineralocorticoid production normal (Aldosterone production influence by R.A.S. No electrolyte abnormalities) No hyperpigmentation (ACTH levels not high) |
Secondary Adrenal Insufficiency
|
|
|
TQ:
Most common cause of Secondary Adrenal Insufficiency |
Abrupt cessation of exogenous glucocorticoid steroids (i.e. Prednisone).
|
|
|
TQ:
Clinical manifestation of Cushing’s Syndrome |
Obesity
Central, facial fat (moon facies) Dorsocervical fat pad (Buffalo hump), not specific Supraclavicular fossa, more specific*** Hypertension Striae, violaceous, wider than 1 cm, abdomen Glucose intolerance |
|
|
TQ:
Work-up of Cushings |
24 urine for Cortisol initially
If elevated cortisol, High dose dexamethasone suppression test (2mg P.O. q6hr x 8 doses) If Cortisol normalizes, Cushing’s disease |
|
|
TQ:
Treatment of Cushing’s Disease |
Cushing’s Disease: Transsphenoidal microadenomectomy
80% curative |
