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50 Cards in this Set

  • Front
  • Back
What methods does visual fields use?

ascending limit
descending limit
constant stimuli
stairstep method
stairstep
In signal detection theory, what does detectability respresent with regard to signal and noise?
Ability to distinguish between noise and signal + noise (sensitivity).
What is sensitivity and specificity?
Sensitivity = true positive (+=+)
-ie. These people have the dz
-For a percentage, divide true positives by total people who have dz (true pos + false neg)

Specificity = true negative (-=-)
-ie. These people don't have dz
What is a type 1 error?
False positive
ie. 1 boy crying wolf
What is a type 2 error?
False negative
ie. excessive skepticism
What is the null hypothesis?
No relationship exists between 2 things. Theory that is put forward to be tested.

Example: There is no difference between new drug and old drug

Result: Reject H0 in favour of H1, or alt hyp (there is a difference; ie. our drug is different!). "Do not reject H0" doesn't mean H0 is true, just that we couldn't prove it wrong.
What is the alternate hypothesis?
There is a difference
What is probability value (p-value)?
Probability of getting a result more often than if by chance alone.

Small p-values less than the set statistical significance (p<0.05 or 0.01, or less than 5 or 1%) suggest that the results are statistically significant (reject null hypothesis).
How does strict criteria affect detection theory (false/true positive/negative)
Fewer hits, low false positives.
How does lax criteria affect detection theory (false/true positive/negative)
High hits, high false positives. Rarely miss a signal that's actually present.
Difference between radiometry and photometry?
Radiometry = energy per time of light (electromagnetic radiation; W)

Photometry = how our visual system responds to light (lumens).
Our visual system is most responsive to what wavelength in photopic conditions?
555 nm produces 680 lumens/watt
Our visual system is most responsive to what wavelength in scotopic conditions?
507 nm produces 1700 lumens/watt
Illuminance vs luminance?
Illuminance deals with light falling upon a target object (like irradiance but not a measureable quantity; deals w/ our visual system), measured in foot-candles

Luminance deals with luminous power of source (ie light bulb; like radiance), measured in foot-lamberts
What do neutral density filters do?
Reduce all wavelengths equally, thus slowing neural response. Over left eye = pendulum rotates clockwise. Due to Pulfrich phenomenon (ND filter slows down response due to decr illumination in that eye).
Describe affects of changing illuminance, area, and distance exposed to incident light.
Triple illuminance = triple luminance.

Triple diameter = increase incident light by factor of 9.

Double distance = 1/4 illuminance.
Where is the photochromatic interval (difference between scotopic and photopic sensitivies) 0?
650 nm. Here, photopic and scotopic sensitivities are equal. No rod-cone break is present here.
What happens to longer wavelengths as illumination increases (Purkinje shift)?
Appear brighter (shifting from scotopic, peak sensitivity 507 nm, to photopic, 555 nm).

Trick: at night, rods dominate and are best at blue. Everything looks blue at night and we are basically color blind. During the day, we can see red roses better.
What happens with threshold after dark adapting
Decreases (more sensitive). The pigment becomes unbleached (regenerates) and is ready to absorb photons.
How many rhodopsin molecules must be bleached for rods to become saturated?
10 %. That is enough to open the critical number of Na+ channels. Cones don't saturate.
What does Ricco's Law vary when testing sensitivity?
Area and intensity at each given area. Increase area by factor of 3, threshold intensity decreases to 1/9.
What does Bloch's Law vary when testing sensitivity (resolution)?

Which has larger critical duration (less sensitive to flashing light), scotopic or photopic?
Time (temporal summation).

Time pixels are larger in scotopic vision (can't see quick flashes)
What is Stiles-Crawford effect?
Light hitting orthogonal (straight down) to cones is much brighter.
Photoreceptor pigment and wavelength
S cones - cyanolabe - 440 nm (affected by dz quicker, ie glaucoma)
M cones - chlorolabe - 534 nm
L cones - erythrolabe - 564 nm
Rods - rhodopsin - 498 nm
What are the following missing?
Protanope
Deuteranope
Tritanope
Red (L cone, erythrolabe)
Green (M cone, chlorolabe)
Blue/yellow (S cone, cyanolabe)
What are hue and saturation?
Hue is color (wavelength) and desaturation means it becomes closer to white. As brightness increases, our perception of hue changes.
What is the CIE diagram?
Helps determine the resulting color of 2 color mixtures. Draw a line connecting the two, make a point on the line closer to the color with higher amount, connect that point to the central "white" mark and extend to find resultant color.

Bottom left starts w/blue, point is green, right is red.
Protanopia:
-Dimming of colors?
-inher/cong?
-how is spectrum shifted?
-Dimming of colors involving R/G
-Inherited
-L cone spectrum shifted to shorter wavelengths (look greener)
Deuteranopia:
-Dimming of colors?
-inher/cong?
-how is spectrum shifted?
-NO dimming of colors
-Inherited
-M cone spectrum shifted to longer wavelengths (look more red)
What does the X-chrom contact lens do?
Help overcome R/G color deficiencies (it's red; it shifts color towards red)
Under what lighting do you do color testing?
Daylight or Macbeth Illuminant C lamp
What does the Farnsworth D-15 test assess?
Diagnoses all 3 (protan, deutan, tritan), but cannot distinguish between dichromats and anomalous trichromats (both R/G defects).
What does the Nagel Anomaloscope test?

Describe the findings w/each color deficiency.
Distinguish dichromacy and anomalous trichromacy in R/G defects.
-Dichromat (prot/deut) perceive match w/test stimulus along the confusion line (mixture field), but prot increase the intensity while deut don't)
-Protanomalous trichromat - red-weak (must increase intensity of red to achieve match)
-Deuteranomalous trichromat - green-weak

If patient can't match, then he's anomalous!
1) What color do cataracts affect?
2) What color does outer retinal dz affect?
3) What color does inner retinal, opt nerve, visual pathway problems affect?
1) yellow filter blocks blue light
2) B/Y
3) R/G
What is the peak sensitivity for human contrast sensitivity function (the top of the CSF curve)?
What is the high SF cutoff?
Peak: 4 cycles/degree.
Cutoff: 40-60 cyc/degree.
1) What limits our CSF high frequency cutoff?

2) What limits our CSF low frequency cutoff?
1) optical limitations, density of photoreceptors
2) Lateral inhibition from ganglion cells (center surround)
What is MAR in relation to:
-The eye
-20/20 Snellen E
-MAR = Minimum Angle of Resolution = inverse of Snellen = represents the angle (as measured from the eye) between 2 just resolvable points
-Ea 1 of the 5 bars of the Snellen E=1 arcmin
-1 cycle = 2 arc minutes
What does 20/40 mean w/Snellen and MAR?
(p. 188 Schwartz)

Conversion of:
-Snellen to Arcmin
-MAR (arcmin) to degrees, cycles/degree, Snellen
The measurement was taken at 20 ft, the smallest optotype the pt can read subtends 5 arcmin @ 40 ft, the details of this optotype subtend 1 arcmin @ 40 ft, and the pt's MAR is 2 arcmin

-20/40 = 2 arcmin (MAR)
-1 arcmin = 1/60 degree = 30 cyc/degree = inverse Snellen
Shortcut to converting snellen to cycles/degree and MAR
MAR (arcmin) is the inverse of Snellen
Divide 600 by cyc/degree to get Snellen
eg. 4 cyc/degree to Snellen
600/4=150=20/150 Snellen
eg. 20/150 to cyc/degree
600/150 = 4 cyc/degree
How many cycles/degree can a typical adult see?
40-60 cycles/degree (MAR = 0.75)
What is uncrossed retinal disparity?
Object is beyond fixation, falling on nasal retina.
What pathway processes motion, and what area does it end up in?
-Magno pathway
-V5 (temporal area, MT)
What happens in motion aftereffects?
After watching motion, such as waterfall, you become less sensitive to it and when stopped, the stimuli appears to move in opposite direction.
Bezold Brucke phenomenon
Perceived hue is closely tied with the luminance of an object, and increasing the luminance will alter a person's perception of hue. The phenomenon goes by the name Bezold Brucke.
Photopic system critical duration?
Scotopic?
Photopic: 10 msec
Scotopic: 100 msec

With a stimulus shorter than these numbers, threshold changes linearly w/flash duration. If stimulus is longer, it almost changes linearly (just slightly less than)
Broca Sulzer effect
The Broca-Sulzer effect says that light flashes of duration 50-100 msec appear brighter than flashes of other durations. That is, there is a peak in the perceived brightness vs. duration curve, and the peak occurs at t approximately 50-100 msec.
How long does it take for cones to dark adapt (ie rod-cone break on adaptation curve)?

Rods?
Cones: 10 min

Rods: 30-40 min
Describe inheritance of R/G defect
X-linked recessive.
If dad has it and mom is carrier, son has 50% chance of getting it. Daughter either has it or is a carrier.
Weber's Law
Weber's law says that the increment threshold is directly proportional to background intensity (or luminance) under photopic vision (see Region E of the light adaptation curve).
Review all the laws at the end of the chapter (p.238)
Ferry-Porter
etc