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16 Cards in this Set

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Define STS
Sarcomas involving the soft tissues, such as muscles, tendons, fat, fibrous tissue, synovial tissue, vessels, and nerves
Define Sarcoma
Cancers arising from mesenchymal tissue such as muscle or bone, which may affect the bones, bladder, kidneys, liver, lungs, parotids, and spleen.
4 distinc groups of sarcoma
1.Soft tissue sarcomas (the focus of this learning system)
2. Bone sarcomas (osteosarcomas and chondrosarcomas) 3.Ewing's sarcomas (occur both in and outside of bone)
4.Peripheral primitive neuroectodermal tumors (occur in limbs,pelvis, and chest wall)
2 general groups of sarcoma
1. Sarcomas of soft tissues (including fat, muscle, nerve and nerve sheath, blood vessels, and other connective tissues)
2. Sarcomas of bone
Types of STS
Sarcomas of adipose tissue
Sarcomas of fibrous tissue
Sarcomas of synovial tissue (considered sarcoma unknown origin)
Sarcomas of smooth muscle
Sarcomas of skeletal muscle
Sarcomas of blood vessels and lymphatics
Sarcomas of peripheral nervous tissue
Sarcomas of unknown origin
2 most prevalent types of STS
sarcomas of unknown origin and those that originate in fibrous tissue are the most prevalent
Most common STS
Based on the estimates from previous data, the most common types of soft tissue sarcoma (eachaccounting for at least 5% of all soft tissue sarcomas diagnosed) are the following:
- Liposarcomas (16%), occur in adipose tissue
- Malignant fibrous histiocytoma (15%), occurs in fibrous tissue
- Leiomyosarcomas (14%), occur in smooth muscle
- Fibrosarcomas (6%), occur in fibrous tissue
- Synovial sarcomas (6%), occur in synovial tissue
60% of cases occur?
In extremeties
4 basic types of body tissue
1.Epithelial tissue (category not containing soft tissues)
2.Connective tissue (category containing soft tissues)
3.Muscle tissue (category containing soft tissues)
4.Nervous tissue (category containing soft tissues)
Most STS develop within this tissue
most soft tissue sarcomas develop within tissues of
mesodermal origin
3 primary germ layers
the endoderm, mesoderm, and ectoderm
Whats is a soft tissue
refers to muscles, tendons, fat, fibrous tissue, blood vessels, synovial tissue, and nerves.
Most abundant tissue
Connective tissue (50%)
4 major types of connective tissue
Connective tissue proper (includes fat and fibrous tissue)
Cartilage
Bone tissue
Liquid connective tissue (blood/lymph)
What is cartilage
consists of a dense network of collagen fibers and elastic fibers firmly embedded in chondroitin sulfate, a gel-like
substance.
-Cartilage can endure more stress than loose and dense connective tissues. The strength of cartilage is due to
its collagen fibers; its ability to retain its shape is due to
chondroitin sulfate
Is Bone considered a soft tissue?
No