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53 Cards in this Set

  • Front
  • Back
plasma membrane
the outer layer of the cell
selective permeability
it allows some substances to cross it more easily than others
amphipathic molecule
has both hydrophobic and hydrophilic regions
fluid mosaic model
the membrane is a fluid structure with a "mosaic" of various proteins embedded in or attached to a double layer (bilayer) of phospholipids
how is the membrane held together?
through weak hydrophobic interactions which make it fluid
When the temperature decreases, the fluidity of the membrane ....
the membrane is liquid until the phospholipids are closely packed enough to form a solid
unsaturated hydrocarbon tails make the temperature at which the phospholipid bilayer stays liquid ...
lower
steroid and membrane temperature
it usually makes the membrane more solid at relatively warm temperatures
Integral proteins
penetrated the hydrophobic core of the lipid bilayer. They are transmembrane proteins which span the whole bilayer
What do the hydrophobic regions of the integral proteins consist of?
one or more nonpolar amino acids, usually coiled into alpha helixes
Peripheral proteins
are not embedded in the lipid layer at all,they are appendages loosely bound to the surface of the membrane
What are the six major functions performed by proteins of the plasma membrane?
Transport, Enzymatic activity, Signal Transduction, Cell-cell recognition, Intercellular joining, Attachment to the cytoskeleton and extracellular matrix(ECM)
How are the proteins held in place on the cytoplasmic side of the plasma membrane?exterior side?
by attachment to the cytoskeleton, are attached to fibers of the extracellular matrix
Why is cell-cell recognition important to cells?
sorting cells into tissues and organs, identifying foreign cells, etc
carbohydrates on the membrane
usually short branched chains of fewer that 15 sugar units
glycolipids
carbohydrate covalently bonded to a lipid on the membrane
glycoproteins
most carbohydrates are covalently bonded to proteins
How do the inside and outside faces of the lipid bilayer differ?
they have differ in specific lipid composition, each protein has directional orientation in the membrane
For which kind of molecule is the membrane really hard to go through?
hydrophilic molecules which find it hard to permeate through the hydrophobic core, so they need assistance to get through the plasma membrane
What is one way for a hydrophilic molecule to get through the plasma membrane?
transport proteins
transport proteins
some are called channel proteins as they serve as a tunnel for polar of ionic molecules to pass through
aquaporins
the passage of water molecules through the membrane in certain cells
carrier proteins
hold onto their passengers and change shape in a way that shuttles them across the membrane
diffusion
the tendency for molecules of any substance to spread out evenly into the available space
concentration gradient
a substance will diffuse from where it is more to where it is less
diffusion: with or against concentration gradient?
with concentration gradient
What does diffusion eventually establish?
An equilibrium, so it may be directional to establish an equilibrium
passive transport
diffusion is passive transport as the cell does not expend energy
osmosis
the diffusion of water through a selectively permeable membrane
tonicity
the ability of a solution to cause a cell to gain or lose water
isotonic, apply to cell environment.
the water and the solute concentrations are equal, so there will be equal movement across the membrane, and no net movement
hypertonic, apply to cell environment
the solute concentration is higher outside, which cause the water to travel outside of the cell and the cell will shrivel up and die
hypotonic, apply to cell environment
the solute concentration is lower outside and higher inside so the water will flow inside and the cell will probably swell and lyse
osmoregulation
the control of water balance, this is needed when organisms without a rigid cell wall live in a hypertonic or hypotonic environment
turgid
very firm, plant cells, when water enters the cell, the elastic wall will only stretch until it exerts back pressure on the cell and opposes further water uptake
flaccid
very limp, if a plant's cells and their surrounding are isotonic then there will be no net movement of water across the membrane which causes the cell to become very limp
facilitated diffusion
many polar molecules and ions diffuse passively with the help of transport proteins
ion channels, gated channels
there is a stimulus that causes the channels to open or close, the stimulus can be electrical or chemical
active transport
transport in which the cell expends energy
sodium-potassium pump
exchanges sodium for potassium across the plasma membrane of animal cells
membrane potential
ranges from about -50 to -200 millivolts (mV)
charge of cytoplasm
negative
electrochemical gradient
the combination of forces acting on an ion
ions diffuse down their _______.
electrochemical gradient
electrogenic pump
a transport protein that generates voltage across a membrane
proton pump
the main electrogenic pump of plants, fungi, and bacteria
cotransport
a substance that has been pumped across the membrane by diffusion
exocytosis
a cells secretes macromolecules by the fusion of vesicles with the plasma membrane
endocytosis
the cell takes in macromolecules and particular matter by forming new vesicles from the plasma membrane
ligands
any molecule that specifically binds to a receptor site of another molecule
phagocytosis
a cell engulfs a particle by wrapping pseudopodia around it and packaging it in the vacuole
pinocytosis
the cell "gulps" droplets of extra-cellular fluid into tiny vesicles
receptor-mediated endocytosis
the cells acquire bulk quantities of specific substances, even though those substances may not be very concentrated in areas of the extracellular fluid