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99 Cards in this Set

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What is the purpose of the microscopic portion of the routine UA?

Detect and identify insoluble materials in the urine.

What does the term Sediment refer to?

Cells, casts, crystals, and amorphous deposits.

What are the 9 Cellular Elements?

1)RBC's


2)WBC's


3)Epithelial Cells


4)Fat Droplets/ Lipids


5)Sperm


6)Bacteria


7)Yeast


8)Casts


9)Crystals

What does RBC's indicate?

Bleeding somewhere in the urogenital tract.



It can also indicate Renal Disease, Dysfunction, Infections, Tumors, Lesions, Stone Formation, or Anticoagulant use.

What happens to RBC's in concentrated urine/ Dilute (Akaline) urine?

Concentrated RBCS: Shrink or Crenate



Dilute RBCS: Swell or Lyse

When is RBCS in urine normal?

When female is in heat.



From traumatic sample colection.

How do WBCS enter the urine?

At any point in the urinary tract or from secretions from the genital tract.

What is the normal # of WBCS?

0-5 WBCs per HPF.

What is Pyuria?

Pus (WBCs Neutrophils) in the urine which indicates infection.

What are the two types of Urinary Tract Infections?

Cystitis



Pyelonephritis

What is Cystitis?

-Lower Urinary Tract Infection (Bladder)



Will see WBCs and Bacteria



No casts



Little or no protein on chem. strip

What is Pyelonephritis?

-Upper Urinary Tract Infection (Kidneys, Ureters)



Will see WBCs and Bacteria



Casts will be present (White, mixed, granular, bacterial, epithelial casts)



Protein will be positive on chem. strip

Where are Epithelial Cells found?

They line the inside of the Urogenital Tract.

What are the three types of Epithelial Cells?

-Squamous Epithelial Cells



-Transitional Epithelial Cells



-Renal Epithelial Cells

Where are Squamous Epithelial Cells found?

In the lining of the inside of the lower urethra, and the vagina and the vulva in females and the prepuce in males.

Are Squamous cells significant?

No, they are commonly found.

Where are Transitional Epithelial Cells found?

Lining the inside of the upper urethra, bladder, ureters, and renal pelvis.

Are Transitional cells significant?

Yes, increased number may suggest inflammation.



But clusters of Transitional cells may be seen after Catheterization and Bladder washings.

Where are Renal Epithelial Cells found?

Lining the Nephron through the Collecting Tubules.

Are Renal cells significant?

Normally rare and increased numbers indicate renal disease.



Can be seen with Fevers, Toxins, Inflammations and Infections.

When are Fat Droplets seen and from commonly?

Catheter lubricants or contaminants.



But fat is most commonly seen in cats.

What illnesses are often seen with Fat Droplets?

-Diabetes Mellitus



-Hypothyroidism



-Obesity

Does Sperm have any significance?

No, but still report findings.

What are the two types of bacteria?

-Cocci



-Rod

When is bacteria seen in urine?

When left standing at room temperature.

What does bacteria indicate?

Indicates infection if seen along with WBCs.



Small amounts of Bacteria is normal.

What does Yeast indicate?

Contamination



In rare instances Yeast infections, but RARE.

What are the types of casts?

1) Hyaline Casts


2)Cellular Casts


3)Granular Casts


4)Waxy Casts


5) Fatty Casts

What gives casts their shape?

Their shape results from precipitation of proteins in the tubules of the kidney.



They appear BIG on a microscope, even 10x.

What are Hyaline Casts?

-The most difficult to see casts.



-Dissolve in Akaline urine.



-Seen because of strenuous exercise, fever, poor renal perfusion or general anesthesia.

What are the four types of Cellular Casts?

-WBC



-RBC



-Renal Tubular



-Bacterial

When are WBC Cellular Cast seen?

Most often Neutrophils are in WBC casts.



Most Commonly seen in Pyelonephritis

When are Renal Tubular Cellular Casts seen?

Resulted from destruction or desquamation of the epithelial cells that line the Renal Tubules.

When are RBC Cellular casts seen?

Resulted from Glomerular disease.



They are the most FRAGILE.

When are Bacterial Cellular casts seen?

In Pyelonephritis.

What are the Variations of Granular Casts?

Fine and Course.

What do the Granular casts resembles?

Hyaline Casts.

Where are Granular casts seen?

Renal, Glomerular or Tubular Disease.



Result from the breakdown of cells within the Renal Tubules.

What are the stages on Casts Degeneration?

Cellular Casts --> Granular Casts --> Waxy Casts

What are Waxy Casts?

A serious pathological finding and implies severe renal disease, also called a broad cast or renal failure cast.



Very refractive.



Squared ends.

When are Fatty casts seen?

In cats with Renal Disease and sometimes dogs with Diabetes mellitus.



Large numbers indicate degeneration of Renal Tubules



Glimmer and Glisten

What are some things commonly confused with casts?

-Mucus


-Rolled squamous


-Fibers, hair


-Scratches on slides


-Yeast

What affects crystal formation?

-Urine pH



-Urine Temperature



-Urine SG (Concentration)

How are crystals classified?

By whether they appear in acid urine or alkaline urine.

How are crystals identified?

Shapes and pH of the urine.

What are the Acid Crystals?

-Amorphous Urates


-Calcium Oxalate


-Uric Acid


-Tyrosine


-Leucine


-Cystine

What are the Alkaline Crystals?

-Amorphous Phosphates


-Triple Phosphates


-Ammonium Biurates


-Calcium Carbonate

What are Amorphous Urates?

Seen as shapeless, pink or red granulation.



Low water intake causes Amorphous Urates.



Seen in Acid or Neutral urine

What two forms of Calcium Oxalate crystals?

-Dihydrate



-Monohydrate

What are Dihydrate crystals?

Envelope looking.



Normal in small amounts



Large amounts seen with Urolithiasis

What are Monohydrate crystals?

Fence Picket looking.



Seen in Ethylene Glycol (antifreeze) Poisoning

What is Uric acid crystals?

Seen as plates, or rhombic shapes.

What are Tyrosine crystals?

Seen as fine, dark needles.



Indicates Liver Disease.

What are Leucine crystals?

Oily Spheres



Indicates Liver Disease.

What are Cystine crystals?

6 sided, flat plates.



Seen with Renal Tubular Disorders.

What are Amorphous Crystals?

Seen as a whitish granular precipitate.



UTIs.

What are Triple Phosphates Crystals?

Seen in Akaline, Neutral, or slightly Acidic urine.



Resembles coffin lids and called STRUVITE.



Small amounts normal, but can mean Urolithiasis or Bladder Infection.

What are Ammonium Biurates?

Appear as dark yellow or brown thorny apples.



Seen in animals with Liver Disease and Portocaval Shunts

What are Calcium Carbonate?

Appear as dumbbell shapes.



Commonly and normal seen in Horse and Rabbit urine.

What is the Drug related Crystal?

Sulfonamides.

What are Sulfonamides?

Seen in animals being treated with Sulfonamide Antibiotics.



Can cause Kidney damage.

What is haziness or cloudiness caused by?

Large amounts of WBCs, RBCs, bacteria, crystals, and epis.

What correlates with urine pH?

Types of crystals.

What is caused along with large amounts of blood?

Large amounts of protein.

What happens to urine left at room temp?

Increased: pH, protein, bacteria, and crystals.



Decreased: Casts, ketones, bilirubin.

What disintegrates in alkaline urine?

Casts and WBCs.

What do Ammonium Biurates Crystals look like?

What do Tyrosine Crystals look like?

What do Calcium Oxalate Crystals look like?

What do Triple Phosphate Crystals look like?

What do Transitional Epithelial Cells look like?

What do Waxy Casts look like?

What do Granular Casts look like?

What do Hyaline Casts look like?

Epithelial Cells and 3 types and what they look like?

-Renal


 


-Squamous


 


-Transitional

-Renal



-Squamous



-Transitional

RBC and types and what they look like?

-Intact


 


-Ghost


 


-Crenated

-Intact



-Ghost



-Crenated

RBCs Microscope look?

-Trans Epi Cells


 


-RBC

-Trans Epi Cells



-RBC

Transitional Epithelial Cells and look?

What do Renal Tubular Epithelial Cells look like?

What do Casts?

-Hyaline


-Fine Granular


-WBC


-RBC


-Fatty


-Waxy


-Mucus Threads

-Hyaline


-Fine Granular


-WBC


-RBC


-Fatty


-Waxy


-Mucus Threads

What do Squamous Epithelial Cells look like?

Sqamous Epithelial Cells look like?

What do Renal Cellular Casts look like?

WBC Cast?

RBC Cast?

Fine Granular Cast?

Course Granular Cast?

Fatty Cast?

Akaline Crystals?

-Triple Phos.


-Calcium Carbonate


-Amorphous Phosphate


-Ammonium Biurates

-Triple Phos.


-Calcium Carbonate


-Amorphous Phosphate


-Ammonium Biurates

Ammonium Biurates?

Calcium Carbonate?

Acidic Crystals?

-Leucine


-Tyrosine


-Cystine


-Amorphous Urates


-Uric Acid


-Sodium Urate


-Fat


-Calcium Dihydrate Oxalate

-Leucine


-Tyrosine


-Cystine


-Amorphous Urates


-Uric Acid


-Sodium Urate


-Fat


-Calcium Dihydrate Oxalate

Dihydrate Calcium Oxalate?

Monohydrate Calcium Oxalate?

Cystine?

Tyrosine?

Leucine?

Uric Acid?

Sulfa Drug Crystal?