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83 Cards in this Set

  • Front
  • Back
Other name for vitamin B12
Cobalamin
other name for vitamin C
ascorbic acid
other names for vitamin B6
pridoxine, pyridoxamine, pyridoxal
other name for vitamin B1
thiamine
other names for niacin
nicotinic acid, nicotinamide
other name for vitamin B2
riboflavin
other names for vitamin A
retinol, retinal, retinoic acid, beta-carotene
other names for vitamin D
cholecalciferol, ergocalciferol
other names for vitamin K
menadione, menaquinone, phylloquinone
other name for vitamin E
alpha-tocopherol
active form of folic acid
tetrahydrofolic acid
active forms of vitamin B12
methylcobalamin, deoxyadenosyl cobalamin
active form of vitamin C
ascorbic acid
active form of vitamin B6
pyridoxal phosphate
active form of vitamin B1
thiamine pyrophosphate
active forms of niacin
NAD+, NADP+
active forms of vitamin B2
FMN, FAD
active form of biotin
enzyme-bound biotin
active form of pantothenic acid
coenzyme A
active forms of vitamin A
retinol, retinal, retinoic acid
active form of vitamin D
1,25-dihydroxycholecalciferol
active forms of vitamin K
menadione, menquinone, phylloquinon
active form of vitamin E
any of several tocopherol derivatives
function of folic acid
transfer one carbon units, synthesis of methionine, purines, and thymine
deficiency of folic acid and signs and symptoms
deficiency: megaloblastic anemia, neural tube defects
signs/symptoms: anemia, birth defects
toxicity of folic acid
none
administration of high levels of folate can mask a ? deficiency
b12
function of b12
cofactor for reactions:
homocysteine -> methionine
methymalonyl CoA -> succinyl CoA
deficiency of vitamin B12
pernicious anemia, dementia, spinal degeneration
signs and symptoms of B12 deficiency
megaloblastic anemia, neuropsychiatric symptoms
treatment for pernicious anemia
treat with IM or high dose oral vitamin B12
functions of vitamin C
antioxidant, cofactor for hydroxylation reactions.
proline -> hydroxyproline and lysine -> hydroxylysine in collagen synthesis
deficiency of vitamin C
scurvy
signs and symptoms of vitamin C deficiency
sore, spongy gums, loose teeth, poor wound healing
vitamin B6 functions
cofactor for enzymes, particularly in amino acid metabolism
signs and symptoms of vitamin B6 deficiency
rare. glossitis and neuropathy. (sensory neuropathy occurs at high doses of B12)
vitamin B6 toxicity?
yes
vitamin C toxicity?
no
vitamin B12 toxicity?
no
vitamin B6 deficiency can be induced by...
isoniazid
functions of vitamin B1
Cofactor of enzymes catalyzing:
*pyruvate->acetyl-CoA
*alpha-ketoglutarate -> succinyl CoA
*ribose-5-P + xylulose5-P -> sedoheptulose 7-P + glyceraldehyde 3-P
deficiency of vitamin B1
beriberi, wernicke-korsakoff syndrome (most common in alcoholics)
signs and symptoms of vitamin B1 deficiency
tachycardia, vomiting, convulsions -> beriberi
apathy, loss of memory, eye movements -> wernicke-korsakoff
vitamin B1 toxicity?
no
water-soluble vitamins
folic acid, vitamin B12, vitamin C, vitamin B6, vitamin B1, niacin, vitamin B2, biotin, pantothenic acid
fat-soluble vitamins
vitamin A, vitamin D, vitamin K, vitamin E
Niacin Function
electron transfer
niacin deficiency
pellagra
signs and symptoms of niacin deficiency
dermatitis, diarrhea, dementia
toxicity of niacin?
none
high doses of ? used to treat hyperlipidemia
niacin
function of vitamin B2
electron transfer
deficiency of vitamin B2
rare
signs and symptoms of vitamin B2 deficiency
dermatitis, angular stomatitis
vitamin B2 toxicity?
none
function of biotin
carboxylation reactions
biotin deficiency?
rare
toxicity of biotin?
none
consumption of large amounts of raw egg whites (which contain avidin) can produce a ? deficiency because ?
biotin deficiency because avidin binds biotin
function of pantothenic acid
acyl carrier
pantothenic acid deficiency?
rare
pantothenic acid toxicity?
none
vitamin A functions
maintenance of growth, vision, promotion of growth, differentiation and maintenance of epithelial tissues, gene expression
vitamin A deficiency
impotence, night blindness, retardation of growth, xerophthalmia
signs and symptoms of vitamin A deficiency
increased visual threshold
vitamin A toxicity?
yes
supplementation of what vitamin A derivative is not recommended
beta-carotene
excess vitamin A can cause
increased incidence of fractures
vitamin D function
calcium uptake
vitamin D deficiency
rickets in children, osteomalacia in adults
signs/symptoms of vitamin D deficiency
soft, pliable bones
vitamin D toxicity?
yes
which vitamin is not a true vitamin?
vitamin D - can be synthesized in the skin
vitamin K function
gamma-carboxylation of glutamate residue in clotting and other proteins
vitamin K deficiency
newborns, rare in adults
signs and symptoms of vitamin K deficiency
bleeding
vitamin k toxicity
rare
vitamin ? is produced by intestinal bacteria.
K
parenteral treatment with vitamin ? is recommended at birth
K
function of vitamin E
antioxidant
vitamin E deficiency
rare
signs and symptoms of vitamin E deficiency
red blood cell fragility leads to hemolytic anemia
vitamin E toxicity
none