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37 Cards in this Set
- Front
- Back
Can vitamins be oxidized to produce energy?
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No
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What are the causes of vitamins deficiency?
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1- Inadequate dietary intake.
2- Malabsorption. 3- Absence for the enzymes which transport, activate, & utilize vitamins. 4- Increased demand. 5- Increased excretion. 6- Some drugs. |
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What are the two classes of vitamins?
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1- Fat-soluble.
2- Water-soluble. |
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What are the major fat-soluble vitamins?
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ADEK
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What does the absorption of fat-soluble vitamins require?
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1- Lipids.
2- Bile Salts. |
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Do fat-soluble vitamins require a carrier protein?
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yes
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Where are the fat-soluble vitamins stored?
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liver
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Are the fat-soluble vitamns excreted?
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No
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When do the manifestations of a deficiency of fat-soluble vitamins become manifest?
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When the stores are depleted
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Can the fat-soluble vitamins become toxic?
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Yes, This is called hypervitaminosis.
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How can we prevent the fat-soluble vitamins deficiency?
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Single large dose
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What are the water-soluble vitamins?
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B Complex group and C
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Compounds with Vitamin A activity are called
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Retinoids
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Retinoids are
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polyisoprenoid compunds
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Retinoids have a .... ring
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Beta-inone
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The provitamin of Vitamin A
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Beta-Carotene
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The color of beta-carotenes
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Yellow to orange
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How is Beta-carotene converted to vitamin A?
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Oxidation in the liver = 2 Vitamin A
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Name 3 different compounds with Vitamin A activity?
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Retinol
Retinal Retinoic Acid |
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Oxidation of retinol or retinal to retinoic acid is
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Irreversible
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What are the animal sources of Vitamin A?
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Milk
Butter Egg Yolk Liver Fish Liver oils |
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Animal sources of beta-carotene:
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Corpus luteum
Cow's milk |
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1 IU = ? RE
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0.3 RE = 0.3 * microgram retinal
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Daily Vitamin A requirements for children
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1400-2000 IU
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Daily Vitamin A requirements for females
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4000 IU
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Daily Vitamin A requirements for Males & pregnant females
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5000 IU
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Retinoids are incorporated into
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cholymicrons
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Retinal is required for
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Normal vision
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Retinoic acid is implicated in
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growth and differentiation
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Retinol is necessary for the
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reproductive system
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Beta carotene acts as an
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antioxidant
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Rhodopsin is found in ... in the eye
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rods
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Rhodopsin consists of
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Opsin + 11-cis retinal
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What are the biological functions of Vitamin A?
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1- Vision in dim light.
2- Maintenance of normal epithelium and skin. 3- Sulfation of the mucopolysaccharides in the matrix of bones. 4- They can act as steroid hormones. 5- Retinoic acid's role in growth and differentiation. 6- Beta-carotenes act as antioxidants. |
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What are the manifestations of Vitamin A deficiency:
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1- Nyctalopia.
2- Xerophthalmia. 3- Keratomalacia. 4- Xeroderma. 5- Keratinizing mataplasia. |
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Bitot's spots
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Greyish-white triangular plaques firmly adherent to the conjunctiva.
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Manifestations of hypervitaminosis A
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1- Anorexia and vomiting.
2- Peeling of skin. 3- Painful bones and painful joints. 4- Loss of hair. 5- Enlargement of liver and spleen. |