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6 Cards in this Set
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Vitamin K |
Discovered by Henrik Dam crucial role in blood clotting K for "koagulation" |
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Vitamin K - Forms |
Family of compounds known as Quinones Phylloquinone: K1, form from plant sources Menaquinones: K2, Animal Sources; also produced by intestinal bacteria Menadione: K3, Medicinal form of Vit K that can be toxic to infants |
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Vitamin K - Functions |
Blood clotting -Production of proteins -Require calcium for activation -Cancium binding capacity allows for change Bone Formation Osteocalcin: Imp. to carboxylation of osteocalcin
Low Vit K associated w/ age-related bone loss |
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Vitamin K - Sources |
2 sources: food and bacteria living in our colons Small intestine absorbs vit K Colon absorbs vit K made by bacteria Veggies: Spinach, turnip greens, broccoli Veggie oils: soybean, canola, olive Exposure to light degrades vit K |
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Vitamin K - Deficiency |
Rare in healthy adults Typical diets supplying less than optimal amounts. Lower bone density in women. Increases risk of fractures, hemorrhage People who suffer w/ fat-malabsorption syndrome Megadoses of vit A & E counteract actions of Vit K Newborn babes (breastfed) run risk of vit K defic bc at birth they lack intestinal bacteria that produce the nutrient |
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Vitamin K - Toxicity |
Rare from food No set UL Overdose can cause hemolytic anemia can interfere w/ anticoagulant meds. can occur w/ newborns who receive vit K in form of menadione rather than recommended form, phylloquinone. |