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12 Cards in this Set
- Front
- Back
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Viral Replication
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1)Adsorption - virus attaches to host cell
2)Penetration - virus penetrates host wall 3)Uncoating (eclipse) - DNA is uncoated inside sell, nucleic acid is released 4) Nucleic acid replication and synthesis of protein coat 5) Assembly - host puts virus back together (capsid, then nucleic acid injected) 6)Release - via budding or lysis |
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Host Defenses
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1) Humoral Immunity - prevention (Ab)
2) Cellular Immunity - recovery 3) Interferon - species specific |
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Effects on Host Cell
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1)None
2)Inclusion bodies 3)Giant cells 4)Cell death 5)Proliferation 6) Chromosomal changes |
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1) Treatment
2) Prevention 3) Disinfection |
1) Viral drugs (usu prevention)
2) Vaccination 3) 10% Bleach |
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RNA VIRUSES
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RNA VIRUSES
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Influenza Virus
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flu
Types A & B Avian flu |
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Parainfluenza virus
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Croup (barking cough)
cold, bronchitis, pneumonia short-term immunity usu. in kids |
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Human Metapneumovirus (hMPV)
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croup
pnuewmonia |
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Mumps virus
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Parotitis (inflam. of parotid glands)
MMR vaccine Complication: inflam of testes and sterility in males after puberty |
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Measels virus
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(Rubeola, red measles)
Measles-maculopapular rash -Koplicks spots (in mouth) Subacute sclerosing panencephalitis (SSPE)-related to childhood measles |
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Nipah and Hendra viruses
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Nipah (SE Asia)- assoc w/ pigs
Hendra (Australia)- assoc w/ flying foxes(bats) -> horses ->humans severe respiratory illness |
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Respiratory Syncytial Virus
(RSV) |
lower resp. tract disease in 1-5 yr olds
seasonal pneumonia, bronchitis |
