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12 Cards in this Set

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Viral Replication
1)Adsorption - virus attaches to host cell
2)Penetration - virus penetrates host wall
3)Uncoating (eclipse) - DNA is uncoated inside sell, nucleic acid is released
4) Nucleic acid replication and synthesis of protein coat
5) Assembly - host puts virus back together (capsid, then nucleic acid injected)
6)Release - via budding or lysis
Host Defenses
1) Humoral Immunity - prevention (Ab)
2) Cellular Immunity - recovery
3) Interferon - species specific
Effects on Host Cell
1)None
2)Inclusion bodies
3)Giant cells
4)Cell death
5)Proliferation
6) Chromosomal changes
1) Treatment

2) Prevention

3) Disinfection
1) Viral drugs (usu prevention)

2) Vaccination

3) 10% Bleach
RNA VIRUSES
RNA VIRUSES
Influenza Virus
flu
Types A & B
Avian flu
Parainfluenza virus
Croup (barking cough)
cold, bronchitis, pneumonia
short-term immunity
usu. in kids
Human Metapneumovirus (hMPV)
croup
pnuewmonia
Mumps virus
Parotitis (inflam. of parotid glands)
MMR vaccine
Complication: inflam of testes and sterility in males after puberty
Measels virus
(Rubeola, red measles)
Measles-maculopapular rash
-Koplicks spots (in mouth)
Subacute sclerosing panencephalitis (SSPE)-related to childhood measles
Nipah and Hendra viruses
Nipah (SE Asia)- assoc w/ pigs
Hendra (Australia)- assoc w/ flying foxes(bats) -> horses
->humans
severe respiratory illness
Respiratory Syncytial Virus
(RSV)
lower resp. tract disease in 1-5 yr olds
seasonal
pneumonia, bronchitis