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10 Cards in this Set
- Front
- Back
exotoxins produced by
|
gram postiitve and negative
|
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endotoxins produced by
|
gram NEGATIVE bacilli
|
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how toxic are
exotoxins endotoxins |
exo = STRONGLY toxic
endo = not as much |
|
site of toxin's effect
exo endo |
exo = specific mode is often obscure
endo = similar toxicity for most organs/cells |
|
chemical nature of
endotoxins exotoxins |
exo: protein
endo: lipopolysaccharide |
|
chemical nature of toxin secreted by endotoxins
|
cell-associated lps
|
|
how exotoxins are released
endotoxins? |
exo: secreted
endo: remains bound; released when cell lyses |
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heat lability of
exotoxins endotoxins |
exo = heat-labile; easy to toxoid - inactivate.
endo = heat-stabile; don't inactivate. |
|
host immune response to
exotoxins endotoxins |
exo: easy to neutralize w/ antibody
endo: hard to neutralize w/ antibody |
|
do exotoxins produce fever/confusion in host?
do endo? |
no
yes |