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93 Cards in this Set
- Front
- Back
What are the main diseases for Paramyxoviridae |
Mump
(Morbilivirus) Measles |
|
What are the main diseases for Coronaviridae
|
SARS
|
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What are the main diseases for Bunyaviridae
|
Cache Valley virus
Sand Fly Fever Hemorrhagic Fever Respiratory Disease Encephalitis |
|
What are the main diseases for Togaviridae
|
Rubella
Sindbis |
|
What are the main diseases for Flaviviridae
|
Yellow Fever & HCV
Dengus Fever West Nile virus |
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What are the main diseases for Reoviridae
|
Colorado Tick Fever Virus
African horse sickness (AHSV) Rotavirus |
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What are the main diseases for Picornaviridae
|
Hepatitis A
|
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What type of genome does Paramyxoviridae have
|
ssRNA
(-) non-segmented |
|
What type of genome does Coronaviridae have
|
ssRNA
(+) non-segmented |
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What type of genome does Bunyaviridae have
|
ssRNA
Segmented (-) |
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What type of genome does Togaviridae have
|
ssRNA
(+) non-segmented |
|
What type of genome does Flaviviridae have
|
ssRNA
(+) non-segmented |
|
What type of genome does Reoviridae have
|
dsRNA
segmented |
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What type of genome does Picornaviridae have
|
ssRNA
(+) |
|
Is Paramyxoviradae enveloped and if so where does the envelope come from
|
YES
(plasma membrane) |
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Is Coronaviradae enveloped and if so where does the envelope come from
|
YES
(RER and/or Golgi) |
|
Is Bunyaviradae enveloped and if so where does the envelope come from
|
YES
(Golgi) via exocytosis |
|
Is Togaviradae enveloped and if so where does the envelope come from
|
YES
(cytoplasmic vesicles) |
|
Is Flaviviradae enveloped and if so where does the envelope come from
|
YES
(RER) |
|
Is Reoviradae enveloped and if so where does the envelope come from
|
No
|
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Is Birnaviradae enveloped and if so where does the envelope come from
|
No
|
|
Is Picornaviradae enveloped and if so where does the envelope come from
|
NO
|
|
What is the capsid morphology of Parmyxoviridae
|
“herringbone” helical
(pleomorphic spherical or filamentous virion) |
|
What is the capsid morphology of Coronaviridae
|
Helical
(pleomorphic spherical virion) |
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What is the capsid morphology of Bunyaviridae
|
Helical (spherical virion)
|
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What is the capsid morphology of Togaviridae
|
Icosahedral (spherical virion)
|
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What is the capsid morphology of Flaviviridae
|
Icosahedral
(spherical virion) |
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What is the capsid morphology of Reoviridae
|
2 concentric capsids
I = icosahedral O = spherical |
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What is the capsid morphology of Picornaviridae
|
icosahedral to spherical virion
|
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What is the mode of entrance for Paramyxoviridae
|
Fusion
(F protein) |
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What is the mode of entrance for Coronaviridae
|
Fusion
(S protein) & RM endocytosis |
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What is the mode of entrance for Bunyaviridae
|
Fusion
|
|
What is the mode of entrance for Togaviridae
|
RM endocytosis
|
|
What is the mode of entrance for Flaviviridae
|
RM endocytosis
|
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What is the mode of entrance for Reoviridae
|
RM endocytosis
|
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What is the mode of entrance for Birnaviridae
|
RM endocytosis
|
|
What is the mode of entrance for Picornaviridae
|
RM endocytosis
|
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How does paramyxoviridae exit the cell
|
Budding PM & Syncytia formation
|
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How does Coronaviridae exit the cell
|
Exocytosis (fusion of cytoplasmic vesicles) & Syncytia formation
|
|
How does Bunyaviridae exit the cell
|
Exocytosis
Cytolysis |
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How does Togaviridae exit the cell
|
Bud into cytoplasmic vesicles - cytolysis
|
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How does Flaviviridae exit the cell
|
Cytolysis & Exocytosis (bud from RER)
|
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How does Reoviridae exit the cell
|
Cytolysis
|
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How does Picornaviridae exit the cell
|
Cytolysis
|
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How may Bunyaviridae be transmitted
|
Horizontal (mosquito) & Vertical (transplacental)
|
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How may Togaviridae be transmitted
|
Horizontal (mosquito) & Vertical
|
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How may Flaviviridae be transmitted
|
Horizontal (O/F, urogenital, mosquito) & Vertical (transplacental & semen)
|
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How may Reoviridae be transmitted
|
Horizontal & Vertical
AHSV = horiz. only |
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How may Picornaviridae be transmitted
|
Horizontal
FMDV – respiratory, milk/contaminated feed, insemination, iatrogenic SVDV – skin abrasions, O/F |
|
Where are the inclusion bodies for paramyxoviridae located in the host cell
|
Cytoplasmic
CDV- cytoplasmic & nuclear |
|
Which family of virus may undergo intramolecular recombination
|
Picornaviridae
|
|
How many segments of RNA does Birnaviridae have
|
2
|
|
Which family may also be known as - Respiratory enteric orphan virus
|
Reoviridae
|
|
Which 3 families may be arthropod borne
|
Togaviridae
Flaviviridae Bunyaviridae |
|
Which family of virus are known for causing fetal and embryonic death
|
Flaviviridae
|
|
What type of genome does Phleboviridae have, and is it (+) or (-) sense
|
Ambisense ssRNA
(+-) segmented |
|
What type of genome does Rotaviridae have, and is it (+) or (-) sense
|
dsRNA
segmented |
|
What type of genome does Filoviridae have, and is it (+) or (-) sense
|
ssRNA
(-) |
|
What type of genome does Picornavirus (HAV) have, and is it (+) or (-) sense
|
ssRNA
(+) |
|
What type of genome does Hepadonavirus (HBV) have, and is it (+) or (-) sense
|
dsDNA/RNA
|
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What type of genome does Herpes virus have, and is it (+) or (-) sense
|
dsDNA
linear |
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What type of genome does Orthomyxo have, and is it (+) or (-) sense
|
ssRNA
(-) segmented |
|
What type of genome does Papovavirus have, and is it (+) or (-) sense
|
dsDNA
|
|
What type of genome does Polyvirus (POX) have, and is it (+) or (-) sense
|
dsDNA
|
|
What type of genome does Retrovirus have, and is it (+) or (-) sense
|
ssRNA
(+) |
|
What type of genome does Rhabdovirus have, and is it (+) or (-) sense
|
ssRNA
(-) |
|
Which virus binds to antibodies to suppress the immune response?
|
Filovirus
|
|
What are the main diseases for Adenoviridae
|
Upper Respiratory Tract Infections - cold
|
|
What are the main diseases for Rotavirus
|
African Horse Sickness
Blue TOngue Colorado Tick Fever Haemorrhagic Fever |
|
What are the main diseases for Hepadonavirus (HBV)
|
Hepatitis
|
|
What are the main diseases for Orthomyxovirus
|
Flu
Influenza A & B "Spanish flu" |
|
What are the main diseases for Papillomavirus
|
Warts/Tumor
|
|
What are the main diseases for Polyvirus
|
Small Pox
|
|
What are the main diseases for Rhabdoviruses
|
Rabies
|
|
Which virus suppress host cell antiviral responses
|
Influenza (Orthomyxoviridae)
|
|
Herpesvirus: Alpha-
Herpes Simplex Virus (HSV-1) HSV-2 Varicella Zoster Virus (VZV) - |
HSV-1: oral/ocular lesion
HSV-2: genital/anal lesions VZV: chicken pox/shingles |
|
Herpesvirus: Beta-
Cytomegalovirus (CMV, HHV-5) Muromegalovirus Roseolovirus (HSV-6, HSV-7) |
CMV:
HHV-6 |
|
Herpesvirus: Gamma-
Lymphocryptovirus Rhadinovirus (HHV-8) Epstein Barr Virus (EBV) |
Lymphocryptovirus: Infectious Mononucleosis
HHV-8: Kaposi's sarcoma EBV: Infectious Mononucleosis |
|
Disease associated with Filovirus
|
Ebola
Marburg via Direct contact |
|
Filoviridae host/reservoir
|
Fruit Bat
|
|
Filoviridae Disease Symptom
|
Fever
Hemorrhage Liver Dysfunction Intravascular Coagulation Shock |
|
Bunyavirus host
|
Between animal via arthropod (mosquitoes & ticks)
|
|
Bunyavirus may evolve by
|
genetic drift
genetic shift |
|
Two genera of Orthomyxoviridae
|
Thogotovirus - ticks
Isavirus - fish |
|
What is the capsid morphology of Orthomyxovirus
|
6~8 segments wrapped in helica nucleocapsids
Lipid membrane |
|
What are:
Antigenic drift Antigenic shift |
Slow continuous accumulation of point mutations
Results from reassortment of genes during a mixed infection with two or more subtypes |
|
DNA Genome virus
|
Herpes
Adeno Hepadna (HBV) Parvo (Parvo, Dependo) Papova (Papilloma, Polyoma) |
|
(+) RNA genome virus
|
Toga
Flavi Corona Picorna (HAV) Picorna Retro |
|
(-) RNA genome virus
|
Bunya
Filo Orthomyxo Paramyxo Rhebdo |
|
Ambisense RNA genome virus
|
Arena
Phlebo |
|
DNA & RNA genome virus
|
Hepadnavirus (HBV)
|
|
What type of genome does Parvovirus have, and is it (+) or (-) sense
|
ssDNA
|
|
Polyvirus (POX) = small pox
(Herpes) VZV = chicken pox |
True
|