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93 Cards in this Set

  • Front
  • Back

What are the main diseases for Paramyxoviridae

Mump

(Morbilivirus) Measles
What are the main diseases for Coronaviridae
SARS
What are the main diseases for Bunyaviridae
Cache Valley virus
Sand Fly Fever

Hemorrhagic Fever
Respiratory Disease
Encephalitis
What are the main diseases for Togaviridae
Rubella
Sindbis
What are the main diseases for Flaviviridae
Yellow Fever & HCV
Dengus Fever
West Nile virus
What are the main diseases for Reoviridae
Colorado Tick Fever Virus
African horse sickness (AHSV)
Rotavirus
What are the main diseases for Picornaviridae
Hepatitis A
What type of genome does Paramyxoviridae have
ssRNA
(-)
non-segmented
What type of genome does Coronaviridae have
ssRNA
(+)
non-segmented
What type of genome does Bunyaviridae have
ssRNA
Segmented
(-)
What type of genome does Togaviridae have
ssRNA
(+)
non-segmented
What type of genome does Flaviviridae have
ssRNA
(+)
non-segmented
What type of genome does Reoviridae have
dsRNA

segmented
What type of genome does Picornaviridae have
ssRNA
(+)
Is Paramyxoviradae enveloped and if so where does the envelope come from
YES
(plasma membrane)
Is Coronaviradae enveloped and if so where does the envelope come from
YES
(RER and/or Golgi)
Is Bunyaviradae enveloped and if so where does the envelope come from
YES
(Golgi)
via exocytosis
Is Togaviradae enveloped and if so where does the envelope come from
YES
(cytoplasmic vesicles)
Is Flaviviradae enveloped and if so where does the envelope come from
YES
(RER)
Is Reoviradae enveloped and if so where does the envelope come from
No
Is Birnaviradae enveloped and if so where does the envelope come from
No
Is Picornaviradae enveloped and if so where does the envelope come from
NO
What is the capsid morphology of Parmyxoviridae
“herringbone” helical
(pleomorphic spherical or filamentous virion)
What is the capsid morphology of Coronaviridae
Helical
(pleomorphic spherical virion)
What is the capsid morphology of Bunyaviridae
Helical (spherical virion)
What is the capsid morphology of Togaviridae
Icosahedral (spherical virion)
What is the capsid morphology of Flaviviridae
Icosahedral
(spherical virion)
What is the capsid morphology of Reoviridae
2 concentric capsids
I = icosahedral
O = spherical
What is the capsid morphology of Picornaviridae
icosahedral to spherical virion
What is the mode of entrance for Paramyxoviridae
Fusion
(F protein)
What is the mode of entrance for Coronaviridae
Fusion
(S protein) &
RM endocytosis
What is the mode of entrance for Bunyaviridae
Fusion
What is the mode of entrance for Togaviridae
RM endocytosis
What is the mode of entrance for Flaviviridae
RM endocytosis
What is the mode of entrance for Reoviridae
RM endocytosis
What is the mode of entrance for Birnaviridae
RM endocytosis
What is the mode of entrance for Picornaviridae
RM endocytosis
How does paramyxoviridae exit the cell
Budding PM & Syncytia formation
How does Coronaviridae exit the cell
Exocytosis (fusion of cytoplasmic vesicles) & Syncytia formation
How does Bunyaviridae exit the cell
Exocytosis
Cytolysis
How does Togaviridae exit the cell
Bud into cytoplasmic vesicles - cytolysis
How does Flaviviridae exit the cell
Cytolysis & Exocytosis (bud from RER)
How does Reoviridae exit the cell
Cytolysis
How does Picornaviridae exit the cell
Cytolysis
How may Bunyaviridae be transmitted
Horizontal (mosquito) & Vertical (transplacental)
How may Togaviridae be transmitted
Horizontal (mosquito) & Vertical
How may Flaviviridae be transmitted
Horizontal (O/F, urogenital, mosquito) & Vertical (transplacental & semen)
How may Reoviridae be transmitted
Horizontal & Vertical
AHSV = horiz. only
How may Picornaviridae be transmitted
Horizontal
FMDV – respiratory, milk/contaminated feed, insemination, iatrogenic
SVDV – skin abrasions, O/F
Where are the inclusion bodies for paramyxoviridae located in the host cell
Cytoplasmic

CDV- cytoplasmic & nuclear
Which family of virus may undergo intramolecular recombination
Picornaviridae
How many segments of RNA does Birnaviridae have
2
Which family may also be known as - Respiratory enteric orphan virus
Reoviridae
Which 3 families may be arthropod borne
Togaviridae
Flaviviridae
Bunyaviridae
Which family of virus are known for causing fetal and embryonic death
Flaviviridae
What type of genome does Phleboviridae have, and is it (+) or (-) sense
Ambisense ssRNA
(+-)
segmented
What type of genome does Rotaviridae have, and is it (+) or (-) sense
dsRNA

segmented
What type of genome does Filoviridae have, and is it (+) or (-) sense
ssRNA
(-)
What type of genome does Picornavirus (HAV) have, and is it (+) or (-) sense
ssRNA
(+)
What type of genome does Hepadonavirus (HBV) have, and is it (+) or (-) sense
dsDNA/RNA
What type of genome does Herpes virus have, and is it (+) or (-) sense
dsDNA
linear
What type of genome does Orthomyxo have, and is it (+) or (-) sense
ssRNA
(-)
segmented
What type of genome does Papovavirus have, and is it (+) or (-) sense
dsDNA
What type of genome does Polyvirus (POX) have, and is it (+) or (-) sense
dsDNA
What type of genome does Retrovirus have, and is it (+) or (-) sense
ssRNA
(+)
What type of genome does Rhabdovirus have, and is it (+) or (-) sense
ssRNA
(-)
Which virus binds to antibodies to suppress the immune response?
Filovirus
What are the main diseases for Adenoviridae
Upper Respiratory Tract Infections - cold
What are the main diseases for Rotavirus
African Horse Sickness
Blue TOngue
Colorado Tick Fever
Haemorrhagic Fever
What are the main diseases for Hepadonavirus (HBV)
Hepatitis
What are the main diseases for Orthomyxovirus
Flu
Influenza A & B
"Spanish flu"
What are the main diseases for Papillomavirus
Warts/Tumor
What are the main diseases for Polyvirus
Small Pox
What are the main diseases for Rhabdoviruses
Rabies
Which virus suppress host cell antiviral responses
Influenza (Orthomyxoviridae)
Herpesvirus: Alpha-
Herpes Simplex Virus (HSV-1)
HSV-2
Varicella Zoster Virus (VZV) -
HSV-1: oral/ocular lesion
HSV-2: genital/anal lesions
VZV: chicken pox/shingles
Herpesvirus: Beta-
Cytomegalovirus (CMV, HHV-5)
Muromegalovirus
Roseolovirus (HSV-6, HSV-7)
CMV:
HHV-6
Herpesvirus: Gamma-
Lymphocryptovirus
Rhadinovirus (HHV-8)
Epstein Barr Virus (EBV)
Lymphocryptovirus: Infectious Mononucleosis
HHV-8: Kaposi's sarcoma
EBV: Infectious Mononucleosis
Disease associated with Filovirus
Ebola
Marburg

via Direct contact
Filoviridae host/reservoir
Fruit Bat
Filoviridae Disease Symptom
Fever
Hemorrhage
Liver Dysfunction
Intravascular Coagulation
Shock
Bunyavirus host
Between animal via arthropod (mosquitoes & ticks)
Bunyavirus may evolve by
genetic drift
genetic shift
Two genera of Orthomyxoviridae
Thogotovirus - ticks
Isavirus - fish
What is the capsid morphology of Orthomyxovirus
6~8 segments wrapped in helica nucleocapsids

Lipid membrane
What are:
Antigenic drift

Antigenic shift
Slow continuous accumulation of point mutations

Results from reassortment of genes during a mixed infection with two or more subtypes
DNA Genome virus
Herpes
Adeno
Hepadna (HBV)
Parvo (Parvo, Dependo)
Papova (Papilloma, Polyoma)
(+) RNA genome virus
Toga
Flavi
Corona
Picorna (HAV)
Picorna
Retro
(-) RNA genome virus
Bunya
Filo
Orthomyxo
Paramyxo
Rhebdo
Ambisense RNA genome virus
Arena
Phlebo
DNA & RNA genome virus
Hepadnavirus (HBV)
What type of genome does Parvovirus have, and is it (+) or (-) sense
ssDNA
Polyvirus (POX) = small pox
(Herpes) VZV = chicken pox
True