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6 Cards in this Set

  • Front
  • Back
Adenovirus:

1) Envelope/nonenveloped?
2) Shape?
3) How often is it found in the population?
4) Who does it most commonly occur in?
5) What do scientists use it for?
6) Main clinical manifestations?
1) Nonenveloped
2) Icosahedral
3) Ubiquitous - found everywhere, most people catch it and catch it early
4) Children - most people have antibodies against adenoviruses by 3
5) Gene therapy
6) Pink eye (highly contagious), gastroenteritis (7-15%), pharyngitis, URI
Pox virus

1) Envelope/nonenveloped?
2) Shape?
3) What 3 major diseases does it cause?
1) Naked
2) Large brick shaped
3)
a)Variola major - smallpox
b) Vaccinia - cowpox
c) Molluscum contagiosum - epidermal tumors that are common in children and benign
Smallpox

1) What is it caused by?
2) What kind of transmission?
3) How is it contracted?
4) Vaccine?
5) What is it characterized by, and how do you know that this is specifically smallpox?
6) Where are lesions usually present?
1) Variola major (poxvirus)
2) Person to person
3) Contact with oral/nasal secretions, lesion material
4) Effective vaccine, half life of antibody = 92 years
5) Lesions -> vesicles -> pustules -> scabs, all pocks are in same developmental stage.
6) Densest on face and extremities (arms and hands, legs and feet) - usually present on palms and soles
Vaccinia

1) What category of virus is it?
2) What does it cause?
3) How does it usually occur, and in who?
1) Poxvirus
2) Cowpox
3) Immunodeficient patients who were accidentally immunized, congenital vaccinia following vaccination. Can contract from being in contact with people who were vaccinated.
HHV 6 & 7:

1) What cell is the main target?
2) How similar are they?
3) Where is it found? Is it active?
4) What disease is each associated with?
1) T-lymphocyte
2) Closely related, like HSV1 and HSV2
3) Ubiquitous, latent disease
4) HHV-6 = Roseola Infantum, HHV-7 = no known disease
How many people worldwide are infected with HepB?

US?

What is the pattern of HepB infections in the US?
350 million worldwide, 1.4 million US

Rates are falling, but still prevalent in people with high risk behavior. 78,000 new infections/year