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18 Cards in this Set
- Front
- Back
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5. Enzymes to replicate the viral genome |
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What is the template for synthesis of viral mRNA in host machinery? a. single stranded RNA b. single stranded DNA c. double stranded RNA d. double stranded DNA |
d. double stranded DNA |
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1. dsDNA |
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1. (+)ss RNA genomes may be translated to make viral protein |
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How are (+)ssRNA viruses replicated? |
(+)ss RNA > (-)ssRNA (-)ssRNA > (+)ssRNA * Need to make - from +, and then make more desired + from the produced - |
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5. All of the above. |
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3. The bonding contacts of subunits are usually non-covalent |
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5. All of the above |
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3. Diffusion of virus particles on the cytoplasm |
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4. The endosome becomes acidified |
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1. RdRp (rna dependent rna polymerase) may initiate de novo or require a primer |
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3. Circularization of template for initiation of RNA synthesis Polio virus is a + RNA that is converted to - rNA and back to + RNA and also virus particles can be created. Primer required, VRG Elim: 1. x, mRNA same as genome in + RNA viruses 2. x, occurs w/ primer (VRG) 3. correct 4. x |
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Classification of viruses? |
> nucleic acid = RNA or DNA = segmented or non segmented = linear or circular = SS or DS (if SS: + sense (translatable), - sense (complementary to mRNA) > capsid > presence of envelope > replicative strategy |
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Viral RNA does not undergo which of the following processes? a. poly adenylation b. 5' capping c. removal of all introns d. export into the cytoplasm e. degradation if not needed |
c. removal of all interns Expl: There is partial splicing (some introns remain on the viral mRNA), everything else remains. a, b, d, e: correct c: incorrect (right answer) |
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Describe different RNA polymerases |
RNA poly I: pre-rRNA RNA poly II: pre-mRNA RNA poly II: pre-tRNA |
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What binds to the TATA sequence? a. TFIa b. TFIIa c. TFIIb d. TFIId e. TFIIIb |
TFIId |
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The vast majority of regulation occurs at what level? a. DNA replication b. transcription c. post transcriptional modification d. translation e. post translational modification |
b. transcription |
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3. Circularization of template for initiation of RNA synthesis |