Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
17 Cards in this Set
- Front
- Back
|
describe the structure and biological properties of Poxiviridae.
|
enveloped
complex morphology larger, linear, ds-DNA genome |
|
|
what human viruses are caused by the family Poxiviridae
|
Variolla (small pox)
Molluscum contagiosum |
|
|
What are the zoonotic viruses caused by Poxiviridae?
|
Vaccinia
Cowpox Orf Monkeypox |
|
|
describe small pox pathology
|
1. respiratory virus infects URT
2. Carried through lymphatic system to lymph node by macrophages (cell-associated viremia) 3. replication at site causes 2nd viremia that spreads the virus throughout the body and produces characteristic rash 4. cell mediated immunity is important |
|
|
True or False
Smallpox is very contagious and infections spread by respiratory routes as well as direct contact. |
True
|
|
|
How many serotypes are found for smallpox?
|
1
|
|
|
True or False
the dried small pox virus is still infectious |
True
|
|
|
Are humans the only host for small pox?
|
yes
|
|
|
Would the infection or the immunization produce lifelong immunity?
|
YES
|
|
|
how is smallpox clinically diagnosed?
|
diagnosed clinically by characteristic pox marks
-an inclusion body called Gyamjeri body can be seen in the infected cells |
|
|
What is the treatment for a patient diagnosed with smallpox?
|
Vaccinia immune globulin is the first line of defense
Cidofovir is the second line of therapy |
|
|
what are some of the major differences between smallpox and chickenpox in the prodromal phase of disease?
|
Smallpox:
1. onset of fever begins as an integral part of the prodromal phase 2. Fever appears 2-4 days before the rash appears 3. constitutional symptoms: severe prostration, abdominal pain, back pain, delirium Chickenpox 1. patient with chickenpox usually have NO fever or other prodromal findings prior to onset of rash |
|
|
Describe the difference between smallpox lesions and chickenpox lesions.
|
Smallpox:
initial lesions appear on the face, in mouth, & pharynx, & forearms. - Smallpox lesions tend to have greatest concentration on arms, legs, palms, and soles -smallpox lesions progress through Stages of Evolution at the same rate **** all lesions in same developmental stage -smallpox lesions progress much more slowly typically 1-2 days for each stage |
|
|
Describe the difference between smallpox lesions and chickenpox lesions.
|
Chickenpox:
rash for chickenpox has centripetal distribution with more lesions on the trunk, with the hands & soles exhibiting few to none lesions Chickenpox lesions are present in all stages at any single location Chickenpox lesions may crust over within 24 hours after the initial macule appears |
|
|
Name other viruses caused by Poxiviridae.
|
Molluscum Contagiosum
Vaccinia cowpox orf monkeypox |
|
|
What is a common name given to Vaccinia?
|
Milker's nodules because it is caused by cowpoxs
|
|
|
What is an interesting fact about Vaccinia?
|
original virus to prevent smallpox
|
