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8 Cards in this Set

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What is the concept of clinical latency
Though a patient may appear well, have a stable CD4 count and partially controlled viral load, the virus is actively destroying CD4 cells in the lymphatics
The opportunistic infections causing morbidity and mortality in HIV patients are often the result of what
Reactivation of latent infections. Appropriate timing of the institution of prophylactic therapy can prolong quality and quantity of life
When is the HIV patient at risk for Pneumocystis pneumonia
CD4<200
When is the HIV patient at risk for toxoplasmosis
CD4<100
When is the HIV patient at risk for Cytomegalovirus and Mycobacterium avium complex
CD4<50
When is primary prophylaxis used for the HIV patient
Life threatening infection, to prevent reactivation. Examples include PCP, MAC, Toxoplasmosis, TB
How often should CD4 count and HIV viral load be monitored
Every 3-6 months. Helps determine when to start treatment, and assess response to antiretrovirals
What are the five classes of HIV drugs
Nucleoside (analogs) reverse transcriptase inhibitors (NRTI)
Nucleotide reverse transcriptase inhibitors
Non nucleoside reverse transcriptase inhibitors (NNRTI)
Protease inhibitors (PI)
Fusion inhibitors