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19 Cards in this Set
- Front
- Back
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what is antibody-dependent enhancement (ADE)
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when preformed antibodies (from first infection) bind to non-neutralizing antigens on virus and enhance viruses ability to enter macrophages (by Fc receptor)
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ADE (antibody-dependent enhancement) occurs in what virus
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dengue
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what causes dengue hemorrhagic fever
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second exposure to virus of a different strain
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sylvan cycle of dengue
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mosquito to monkey
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urban cycle of dengue
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mosquito to human
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genome of arbovirus
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ambisense (mixed + and - sense) ssRNA
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three subclasses of arboviruses
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togavirus
flavivirus (yellow and dengue fever) bunyavirus |
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stamaril
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yellow fever vaccine
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yellow fever is endemic in what regions
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south america
africa |
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black vomit
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yellow fever (blood in stomach from gastric mucosal invasion turns black and is vomitted)
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councilman bodies
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yellow fever (intracellular viral growth in hepatocytes)
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clinical signs of yellow fever
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jaundice
black vomit |
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vector of yellow fever
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mosquito
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vector of dengue fever
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mosquito
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principal site of dengue viral replication
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dendritic cell
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breakbone fever (deep bone pain)
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dengue fever (infection of the bone marrow)
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fever
rash back pain |
dengue fever
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dengue shock syndrome
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spontaneous hemorrhage due to dengue hemorrhagic fever
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causes cytokine storm
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dengue hemorrhagic fever
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