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9 Cards in this Set
- Front
- Back
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Flaviviridae
- Envelope? - Nucleic acid type? - Genomic segmentation? |
Enveloped
Non-segmented genome ss (+) RNA virus |
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Flaviviridae
- genuses of importance - example of disease they provoke |
- Flavivirus
- Pestivirus + Bovine viral diarrhea virus + Hog cholera virus + Border dz virus - Hepacivirus |
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BVDV
- Family - Genus - Mostly infects ... |
Flaviviridae
Pestivirus Mostly infects cattle (feedlots and dairy) Also found in sheep, goats, and wild ruminants BVDV and Border dz cross-infect b/w cattle and sheep |
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What is BVDV characterized by?
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Genetic, antigenic and pathogenic diversity
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What is a viral biotype?
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The characteristic effect of virus replication in cell culture.
pt related to virulence |
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BVDV biotypes
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- Cytopathic
- Non-cytopathic |
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BVDV genotypes
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- Type I
- Type II - peracute hemorrhagic dz Both genotypes contain CP and NCP biotypes Genotype based on sequences in 5' region of viral genome |
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BVDV
Clinical outcome of infection depends on ... |
- Age when infected
- Immune status when infected |
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BVDV
Character of the dz: 3 types |
- Acute infection: infection of seronegative, immunocompetent cattle
- Persistent infection: transplacental infection and immunotolerance - Mucosal dz: results from infection of PIs w/ CP-BVDV |
