Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
21 Cards in this Set
- Front
- Back
|
what is the difference from DNA viruses and RNA viruses?
|
RNA need a viral encoded protein- replicase becase EUKS have no protein in existants to read RNA template
|
|
|
what ss of RNA is more like mRNA
|
(+)
|
|
|
what happens with (+)ss RNA?
|
can be transcribed to make a reverse transcriptase and then is read to make a dsDNA and then read by the host RNA polymerase
|
|
|
then what happens with (-) ssRNA viruses?
|
they have to bring a reverse transcriptase with them. this is given when the complementary ds RNA is expressed.
|
|
|
why do viruses have so many mutations?
|
viral proteins such as reverse transcriptase are error prone.
|
|
|
influenza is most severly caused by which type?
|
A, you get the flu
|
|
|
what are flu symtoms?
|
fever, muscle ache, headache, cough and chills?
|
|
|
if you have nausea and vomitting do you have a flu?
|
no
|
|
|
what is so weird about the 1918 epidemic?
|
so many people died and alot of young people died too
|
|
|
stucture wise describe the influenza virus?
|
envelop, has N and H
|
|
|
influenza-
hemagglutinin |
attachement
|
|
|
influenza-
neuraminidase |
aids in release from host
|
|
|
antigenic drift
|
mild, simple mutations
|
|
|
antigentic shift
|
major difference, happens when there is an error in viral packaging and get a mix of virulence factor genes
|
|
|
describe Influenza vaccine
|
based off of circulating H and N, attenuated
|
|
|
polio virus
|
naked virus
ss(+) RNA fecal oral tranmission |
|
|
what can polio infect and what antibodies are involved?
|
GI- IgA
Blood-IgG CNS- none |
|
|
endemic polio
|
result of poor sanitation, seen in kids, and is rarely paralytic because protected by mother's IgG
|
|
|
epidemic polio
|
in the presence of good sanitation, all ages are infected, paralytic prone
|
|
|
polio Sabin vaccine
|
oral
attenuated IgG and IgA response can mutate to be bad herd immunity |
|
|
polio Salk vaccine
|
injected
not alive IgG response |
