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72 Cards in this Set

  • Front
  • Back
Parvoviridae genome type
ssDNA
Papillomaviridae genome type
dsDNA as episome
Adenoviridae genome type
dsDNA
Poxviridae genome type
dsDNA
Herpesviridae genome type
dsDNA as episome or provirus
Asfarviridae genome type
dsDNA
Retroviridae genome type
ssRNA (+) as episome or provirus
Rhabdoviridae genome type
ssRNA (-)
Orthomyxoviridae genome type
ssRNA (-)
Which viruses covered in lecture are non-enveloped?
Parvo, papilloma, adeno, pox
Which viruses covered in lecture are enveloped?
Pox, herpes, asfar, retro, rhabdo, orthomyxo
Which viruses are considered small in size?
Parvo, papilloma
Which viruses are considered medium in size?
Retro, rhabdo, orthomyxo, adeno
Which viruses are considered large in size?
Herpes
Which viruses are considered extra large in size? Which is the largest?
Pox, asfar
Poxviridae are the largest viruses
What is the capsid shape of parvo virus?
icosahedral
What is the capsid shape of papilloma virus?
icosahedral
What is the capsid shape of adeno virus?
icosahedral
What is the capsid shape of pox virus?
complex and non-symmetrical (brick or ovoid shape)
What is the capsid shape of herpes virus?
icosahedral (pleiomorphic)
What is the capsid shape of asfar virus?
icosahdral (spherical)
What is the capsid shape of retro virus?
spherical to rod shaped--helical
What is the capsid shape of rhabdo virus?
helical (bullet shape)
What is the capsid shape of orthomyxo virus?
helical (spherical or filamentous shape)
How does parvo virus gain entry into a cell?
receptor-mediated endocytosis
How does papilloma virus gain entry into a cell?
receptor-mediated endocytosis
How does adenovirus gain entry into a cell?
fiber-cell receptor attachment (VAP) and endocytosis
How does pox virus gain entry into a cell?
fusion or receptor-mediated endocytosis
How does herpes virus gain entry into a cell?
fusion or receptor-mediated endocytosis
How does asfar virus gain entry into a cell?
receptor-mediated endocytosis
How does retro virus gain entry into a cell?
fusion, then receptor-mediated endocytosis
How does rhabdo virus gain entry into a cell?
fusion or receptor-mediated endocytosis
How does orthomyxo virus gain entry into a cell?
receptor-mediated endocytosis via hemagglutinin and neuraminidase
What is the replication site for parvo virus?
nucleus
What is the repilcation site for papilloma virus?
nucleus
What is the replication site for adenovirus?
nucleus
What is the replication site for pox virus?
cytoplasm--entirely independent from the host cell
What is the replication site for herpes virus?
nucleus
What is the replication site for asfar virus?
cytoplasm
What is the replication site for retro virus?
cytoplasm or nucleus (via reverse transcriptase)
What is the replication site of rhabdo virus?
cytoplasm (has own transcriptase)
What is the replication site of orthomyxovirus during the eclipse and maturation phases?
nucleus (eclipse)
cytoplasm (maturation)
Which viruses are released by cytolysis?
parvo, papilloma, adeno, pox, herpes, rhabdo
Which viruses are released by budding (and from where)?
Pox (from golgi), Asfar (from PM), retro (from PM), rhabdo (from PM), orthomyxo (from PM)
Which viruses are released by exocytosis?
Pox, herpes
What is the cell tropism of parvo virus?
high mitotic rate cells like GIT and hematopoietic system
What is the cell tropism of papilloma virus?
integument, mm (digestive, urogenital)
What is the cell tropism of adeno virus?
epithelial cells (especially GIT and respiratory)
What is the cell tropism of pox virus?
epithelial cells (permissive), macrophages (semi-permissive)
What is the cell tropism of herpes virus?
varies with disease; alpha--sensory nerve ganglia; beta and gamma--lymphoid tissue
What is the cell tropism of asfar virus?
lymphoreticular tissue, especially macrophages
What is the cell tropism of retro virus?
WBCs: macrophages, B and T stem cells, lymphocytes
What is the cell tropism of rhabdo virus?
depends on disease; epithelium only (VSV); neurons and secretory epithelium (rabies)
What is the cell tropism of orthomyxo virus?
respiratory (birds and mammals)
GIT (birds only)
What is the incubation period of parvo virus?
short: 2-10 days
What is the incubation period of papilloma virus?
short in permissive cells
long in semi- or non-permissive cells
What is the incubation period of adeno virus?
long: weeks
What is the incubation period of pox virus?
short: less than 7 days (shorter than papilloma)
What is the incubation period of herpes virus?
depends on disease: alpha--short; beta--long; gamma--long
What is the incubation period of asfar virus?
short: 5-15 days
What is the incubation period of retro virus?
very long: months to years
What is the incubation period of rhabdo virus?
long in neurons: 14-90 days
short in epithelium: 1-5 days
What is the incubation period of orthomyxovirus?
very short: hours (virulent avian strains) to a few days
What are the mechanisms of transmission of parvo virus?
hortz: oral-fecal, fomites
vert: transplacental
What are the mechanisms of transmission of papilloma virus?
hortz: direct contact with skin and/or mm
What are the mechanisms of transmission of adeno virus?
hortz: oral-fecal, respiratory, urine
What are the mechanisms of transmission of pox virus?
hortz: direct contact with skin, respiratory, mechanical vectors
What are the mechanisms of transmission of herpes virus?
hortz: direct contact, lactogenic, blood
vert: transplacental
What are the mechanisms of transmission of asfar virus?
hortz: oral-fecal, bite from soft tick (Ornithodoros), respiratory, infected pork
What are the mechanisms of transmission of retro virus?
hortz: immune response initiated
vert: immune response initiated
Requires prolonged contact, so vertical transmission is favored
What are the mechanisms of transmission of rhabdo virus?
hortz: skin or mm lesion
What are the mechanisms of transmission of orthomyxovirus?
hortz: respiratory aerosols, oral-fecal (birds)