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60 Cards in this Set

  • Front
  • Back
Five Functions of the Digestive System
Prehension
Mechanical grinding of food (chewing)
Chemical digestion of food
Absorption of nutrients and water
Elimination of waste
Upper arcade is within the?
maxilla
lower arcade is within the?
Mandible
tooth anatomy
Tube that connects oral cavity to stomach
esophagus
Sphincter is tight enough in horses and rabbits that they can’t
vomit
(no NPO restrictions before rabbit anesthesia…)
the esophagus Enters into the stomach to the left of midline at an angle creating
a gastroesophageal sphincter that is pinched shut when the stomach is distended.
Prevents gastroesophageal reflux.
the esophagus has what kind of muscle
Varying amounts of skeletal and smooth muscle depending on species
Monogastric Stomachs
Cats, dogs, horses, pigs, humans
(monogastric) cardia
where the esophagus drops off the swallowed food
(monogastric) fundus
distends while eating. Left side
(monogastric) pylorus
muscular sphincter between stomach and duodenum. Right side of body. Doesn’t close completely so allows liquids to move through more quickly than solids
Rugae
long ridges of mucosa in the stomach
Monogastric stomach components
cardia, fundus, pylorus, body, lesser curvature, greater curvature,
What are the 2 sphincters in the monogastric stomach?
Gastroesophageal sphincter, pyloric sphincter
Small Intestine
Duodenum – descending, duodenal flexure, ascending
Jejunum
Mesenteric root and lymph nodes
Ileum
Ends at ileocecocolic junction, a sphincter
Mesentery
Goblet cells produce
mucus
Lacteals run through center of
villis
Crypts
where new epithelial cells are produced
Cecum
Small, blind pouch in dogs and cats
Large blind pouch in herbivores
Colon
Ruminant GI system
reticulum, rumen, omasum, abomasum (true stomach, analogous to monogastric stomach)
Rumen
Root word for rumination
Process of regurgitating ingesta from the rumen and “rechewing” it. “Chewing cud”
Takes up all the space in the left abdomen
Rumen
Site of bacterial fermentation as well as protozoal and fungal digestion
Ruminants absorb products of microbial digestion-mainly
volatile fatty acids (VFAs)
VFAs are a major
energy source which are then metabolized by animal
Omasum
Right cranioventral abdomen
Entrance off of the reticulum
Muscular pump between rumen and abomasum
Abomasum
Right cranioventral abdomen
Same function as carnivore stomach
“True Stomach”
Can become displaced in dairy cattle
Abomasum
LDA
left displaced abomasum
rumen shrinks after anorexia, allowing more room for abomasum to move around
RDA
right displaced abomasum
Spontaneous

both left and right are surgical
esophageal groove
Young ruminants have a reticular or esophageal groove that allows milk to completely bypass the rumen. Protects the bacterial composition of the rumen from disruption.
Equine Large Intestine
Right Ventral colon
Sternal flexure
Left ventral colon
Pelvic flexure
Left dorsal colon
Diaphragmatic flexure
Right dorsal colon
Small colon
Small colon and flexures are narrowed and sites of obstruction (colic)
Gallbladder empties via common bile duct into
duodenum
Liver Anatomy
Caudal to the diaphragm

Divided into lobes

Portal vein delivers blood to hepatic sinusoids

Blood flows out of sinusoids into hepatic vein and into caudal vena cava

Bile secreted by hepatic cells collects into canaliculi, then bile ducts, then into gallbladder
Liver Functions
Phagocytic Functions
on blood coming from GI tract before it reaches systemic circulation
Production of Albumin
liver functions
responsible for the maintenance of oncotic pressure
Creates glucose from amino acids
gluconeogenesis
Stores glucose in the form of glycogen
glycogenesis.
Bile
Created by hepatic cells
pancreas exocrine
(secretes substances that go “outside” of the body; requires a duct) – secretes amylase, lipase, and proteases)
pancreas endocrine
secretes insulin and glucagon which regulate glucose levels
Four types of glandular cells in the stomach
parietal, cheif,G, and mucus cells
Parietal cells
– produce hydrochloric acid (HCl)
Chief cells –
produce enzyme precursor pepsinogen
Mucous cells (Goblet cells)
– produce mucus which protects stomach lining
G cells
– produce hormone gastrin
Parietal cell has 3 receptors on “blood” side of epithelium to synchronize acid secretion
1) Gastrin Receptor – gastrin in blood increases HCl secretion

2) Acetycholine Receptor – parasympathetic stimulation of G cells (which produce gastrin) releases acetylcholine

3) Histamine Receptor (H2, vs. H1 which are in respiratory tract)
Blocking any of the 3 receptors leads to decreased acid production
H2 Blockers – Tagamet, Zantac, Pepcid
Atropine
Prostaglandins (PGs)
Most PGs are associated with inflammation

Some reduce gastric HCl production, enhance HCO3 production for the mucous layer and enhance gastric blood flow

Non-steroidal anti-inflammatory drugs (NSAIDs) are PG inhibitors => risk for gastric ulceration with their use
stomach lined with what muscle
smooth muscle
Small Intestinal Digestion
Electrolytes, water, vitamins can be absorbed directly across intestinal epithelium

Carbohydrates, fats and proteins must be broken down into their building blocks
Amylase is the enzyme that digests
carbs
is the process of breaking fat globules into smaller ones, occurs in the antrum of the stomach
Emulsification
hydrophilic end and a hydrophobic end
(Smaller fat globules combine with bile acids and are prevented from separating back again because of)
Bile acids have a
fatty acids/bile acid combinations called
micelles
produced in pancreas penetrate bile coating and break fats into glycerol and fatty acids/bile acids called micelles
Lipases
Secretin – a hormone
1) slows gastric emptying
2) stimulates gallbladder to contract, releasing bile into duodenum
3) stimulates pancreas to release bicarbonate-rich fluid
Cholecystokinin – a hormone
1) Inhibits gastric motility
2) Stimulates GB contraction
3) Stimulates pancreas
increase of a certain kind of digestive enzyme in response to increasing amount of substrate in the diet
Up regulation –
Down regulation
-decrease of a certain kind of digestive enzyme in response to increasing amount of substrate in the diet