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60 Cards in this Set
- Front
- Back
Five Functions of the Digestive System
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Prehension
Mechanical grinding of food (chewing) Chemical digestion of food Absorption of nutrients and water Elimination of waste |
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Upper arcade is within the?
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maxilla
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lower arcade is within the?
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Mandible
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tooth anatomy
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Tube that connects oral cavity to stomach
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esophagus
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Sphincter is tight enough in horses and rabbits that they can’t
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vomit
(no NPO restrictions before rabbit anesthesia…) |
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the esophagus Enters into the stomach to the left of midline at an angle creating
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a gastroesophageal sphincter that is pinched shut when the stomach is distended.
Prevents gastroesophageal reflux. |
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the esophagus has what kind of muscle
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Varying amounts of skeletal and smooth muscle depending on species
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Monogastric Stomachs
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Cats, dogs, horses, pigs, humans
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(monogastric) cardia
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where the esophagus drops off the swallowed food
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(monogastric) fundus
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distends while eating. Left side
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(monogastric) pylorus
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muscular sphincter between stomach and duodenum. Right side of body. Doesn’t close completely so allows liquids to move through more quickly than solids
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Rugae
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long ridges of mucosa in the stomach
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Monogastric stomach components
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cardia, fundus, pylorus, body, lesser curvature, greater curvature,
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What are the 2 sphincters in the monogastric stomach?
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Gastroesophageal sphincter, pyloric sphincter
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Small Intestine
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Duodenum – descending, duodenal flexure, ascending
Jejunum Mesenteric root and lymph nodes Ileum Ends at ileocecocolic junction, a sphincter Mesentery |
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Goblet cells produce
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mucus
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Lacteals run through center of
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villis
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Crypts
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where new epithelial cells are produced
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Cecum
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Small, blind pouch in dogs and cats
Large blind pouch in herbivores Colon |
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Ruminant GI system
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reticulum, rumen, omasum, abomasum (true stomach, analogous to monogastric stomach)
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Rumen
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Root word for rumination
Process of regurgitating ingesta from the rumen and “rechewing” it. “Chewing cud” Takes up all the space in the left abdomen |
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Rumen
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Site of bacterial fermentation as well as protozoal and fungal digestion
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Ruminants absorb products of microbial digestion-mainly
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volatile fatty acids (VFAs)
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VFAs are a major
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energy source which are then metabolized by animal
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Omasum
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Right cranioventral abdomen
Entrance off of the reticulum Muscular pump between rumen and abomasum |
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Abomasum
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Right cranioventral abdomen
Same function as carnivore stomach “True Stomach” |
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Can become displaced in dairy cattle
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Abomasum
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LDA
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left displaced abomasum
rumen shrinks after anorexia, allowing more room for abomasum to move around |
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RDA
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right displaced abomasum
Spontaneous both left and right are surgical |
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esophageal groove
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Young ruminants have a reticular or esophageal groove that allows milk to completely bypass the rumen. Protects the bacterial composition of the rumen from disruption.
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Equine Large Intestine
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Right Ventral colon
Sternal flexure Left ventral colon Pelvic flexure Left dorsal colon Diaphragmatic flexure Right dorsal colon Small colon Small colon and flexures are narrowed and sites of obstruction (colic) |
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Gallbladder empties via common bile duct into
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duodenum
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Liver Anatomy
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Caudal to the diaphragm
Divided into lobes Portal vein delivers blood to hepatic sinusoids Blood flows out of sinusoids into hepatic vein and into caudal vena cava Bile secreted by hepatic cells collects into canaliculi, then bile ducts, then into gallbladder |
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Liver Functions
Phagocytic Functions |
on blood coming from GI tract before it reaches systemic circulation
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Production of Albumin
liver functions |
responsible for the maintenance of oncotic pressure
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Creates glucose from amino acids
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gluconeogenesis
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Stores glucose in the form of glycogen
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glycogenesis.
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Bile
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Created by hepatic cells
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pancreas exocrine
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(secretes substances that go “outside” of the body; requires a duct) – secretes amylase, lipase, and proteases)
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pancreas endocrine
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secretes insulin and glucagon which regulate glucose levels
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Four types of glandular cells in the stomach
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parietal, cheif,G, and mucus cells
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Parietal cells
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– produce hydrochloric acid (HCl)
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Chief cells –
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produce enzyme precursor pepsinogen
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Mucous cells (Goblet cells)
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– produce mucus which protects stomach lining
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G cells
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– produce hormone gastrin
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Parietal cell has 3 receptors on “blood” side of epithelium to synchronize acid secretion
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1) Gastrin Receptor – gastrin in blood increases HCl secretion
2) Acetycholine Receptor – parasympathetic stimulation of G cells (which produce gastrin) releases acetylcholine 3) Histamine Receptor (H2, vs. H1 which are in respiratory tract) |
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Blocking any of the 3 receptors leads to decreased acid production
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H2 Blockers – Tagamet, Zantac, Pepcid
Atropine |
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Prostaglandins (PGs)
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Most PGs are associated with inflammation
Some reduce gastric HCl production, enhance HCO3 production for the mucous layer and enhance gastric blood flow Non-steroidal anti-inflammatory drugs (NSAIDs) are PG inhibitors => risk for gastric ulceration with their use |
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stomach lined with what muscle
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smooth muscle
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Small Intestinal Digestion
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Electrolytes, water, vitamins can be absorbed directly across intestinal epithelium
Carbohydrates, fats and proteins must be broken down into their building blocks |
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Amylase is the enzyme that digests
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carbs
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is the process of breaking fat globules into smaller ones, occurs in the antrum of the stomach
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Emulsification
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hydrophilic end and a hydrophobic end
(Smaller fat globules combine with bile acids and are prevented from separating back again because of) |
Bile acids have a
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fatty acids/bile acid combinations called
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micelles
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produced in pancreas penetrate bile coating and break fats into glycerol and fatty acids/bile acids called micelles
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Lipases
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Secretin – a hormone
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1) slows gastric emptying
2) stimulates gallbladder to contract, releasing bile into duodenum 3) stimulates pancreas to release bicarbonate-rich fluid |
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Cholecystokinin – a hormone
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1) Inhibits gastric motility
2) Stimulates GB contraction 3) Stimulates pancreas |
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increase of a certain kind of digestive enzyme in response to increasing amount of substrate in the diet
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Up regulation –
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Down regulation
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-decrease of a certain kind of digestive enzyme in response to increasing amount of substrate in the diet
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