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25 Cards in this Set

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define virus
self-rreplicating nucleoprotien
What is a viron?
mature (complete) virus particle
This is the smallest amount of virus/volume capable of producing the reaction being measured.
Infectious unit
Which kind of virus induces cytolysis when exiting the cell?
nonenveloped
Which phase msut a cell be in to have the components available for DNA synthesis>
s-phase
This is the viral encoded protein coat surrounding the core.
capsid
This is the capsid and its enclosed core.
nucleocapsid
What are the three envelope proteins?
peplomer
viral attatchment proteins
antigenic proteins
This is a bridge between the nucleocapsid and the internal membrane of the envelope.
matrix protein
what are the four possible cytopathic effects of virus?
cell lysis
syncytia formation
inclusion bodies
transformation
Which assay measurement is either all or none?
quantal
Viral genome integrated into cellular DNA
provirus
viral genome persists in the nucleas as an extrachromosomal element
episome
This is a cell that will support a productive viral infection
permissive cell
This is a cell that will not support a productive viral infection, an abortive infection results, cell may be transformed.
non-permissive cell
This plaque assay measures the actual amount of infectious units per dilution.
quantitative assay
This plaque assay is measured by counting lesions on CAMs of egg embryos.
pock assay
What are the three different plaque assays?
quantitative
pock
cell culture
What does a Virus-serum neutralization assay do?
Estimates the amount of antiviral antibodies that can neutralize viral infectivity.
This modern assay tells you viral specific antigens the body is responding to.
Western Immunoblot
What are the two mechanisms of penetration for a virus?
fushion

receptor mediated endocytosis
What two major things happen during the eclipse phase?
production of viral regulatory enzymes and structural proteins

replication of viral nucleic acid
What are two examples of direct viral infection of immune system effector cells?
lysis of lymphoreticular cells

viral-induced immune cell
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