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40 Cards in this Set

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By what organisms are hemoflagellates usually transmitted?
blood-sucking arthropods
What are the three routes of transmission of hemoflagellates?
salivarian
stercorarian
venereal
What are the hosts of Trypanosoma cruzi?
DH: man, dogs, raccoons, opposums, armadillos...
IH: triatomine or kissing bug
What's the site of infection for Trypanosoma cruzi?
blood early infection
heart, striated muscle, and other tissue
Stercorarian hemoflaggelates?
Trypanosoma cruzi
T. equiperdum
Salivarian hemoflaggellates?
Trypanosoma brucei
Nagana and African sleeping sickness
What is the infective stage of Trypanosoma cruzi?
trypomastigotes
What stage of Trypanosoma cruzi is multiplying intracellularly?
amastigote
Pathogenesis of Trypanosoma cruzi?
cell damage when trypomastigotes rupture out
esp. heart muscle cells
Are most species of Trypanosoma pathogenic
most species are non-pathogenic
How is Trypanosoma equiperdum transmitted ?
sexually transmitted
What is the Geographic distribution of Trypanosoma equiperdum?
eradicated from US and Canada
everywhere else
Hosts of Leishmania?
DH: humans, wild and domestic animals, usually only see in American Fox Hounds
IH: sandflies
Site of infection for Leishmania?
macrophages of host tissue are infected
Dx of Leishmania infantum?
impression smear
what is an apicomplexa and what are the three types I need to know?
organism whose infective stage possesses an apical complex
Coccidia
hemosporidia
Hepatazoon americanum
sporogony
asexual reproduction to form sporozoites
Merogony/schizogony
a form of asexual reproduction that occurs in protozoans, in which the nucleus of an individual divides many times before the cytoplasm divides to form the daughter cells called merozoites
Hosts of Babesia?
IH: mammals
DH: ticks
site of infection of Babesia?
RBC in mammal
routes of transmission for Babesia
In Tick transovarial, transstadial

Blood transfusion
Pathogenesis of Babesia
anemia
clinical dz in young and immunocompromised
Dx of Babesia
prioplasms on stained blood films
PCR
trophozoites decrease with time
Babesia species in dogs
B. canis and B. gibsoni
Hosts for Babesia bigemina
IH: cattle and deer
DH: ticks
zoonotic piroplasm
Babesia microti- NEast and Midwest
tick or blood transfusion
Hosts of Theileria
IH: mammals- mostly ruminats
DH: ticks
Site of infection of Theileria
RBC and lymphocytes in mammal
Geographic distribution of Theileria
world-wide very pathogenic in Africa, Asia and Southern Europe
How is Theileria transmitted?
ticks- transstadial
Where does Theileria undergo schizogony?
lymphocytes prior to entering RBC
Hosts of Cytauxzoon felis
IH: bobcats, ferral cats
Abberant in domestic cats
DH: ticks Dermacentor variabilis and Amblyomma americanum
Site of infection of Cytauxzoon felis
Macrophages and RBC
Geographic distribution of Cytauxzoon felis
South eastern and South central US
Pathogenesis of Cytauxzoon felis
abberant hosts- rapid intravascular multiplication results in mechanical obstruction of blood flow
Hosts of Hepatazoon americanum
canines and ticks ( Amblyomma maculatum)
Site of infection of Hepatazoon americanum
leukocytes
muscle cells
What is the infective stage of Hepatazoon americanum
sporulated oocyst
pathogenesis of Hepatazoon americanum
periosteal bone proliferation
Dx of Hepatazoon americanum
muscle biopsy
blood smear-Gamonts in white blood cells

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