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67 Cards in this Set

  • Front
  • Back
4 Tissue Types
Epithelium
Connective Tissue
Muscle
Nervous tissue
Connective Tissue Composition
Cells
Fibers
Ground substance
Characteristics of Epithelial Tissue
- Fried Egg Appearance
- Lines surfaces of organs and tissues
- Little intercellular space
- Rest on a basement membrane (avascular)
Function of Epithelial Cell
- Protection - skin
- Absorption - lungs, kidney
- Excretion - one-way transport system
- Secretion - serous/mucous and seromucous
- Surface reception - special senses
- Reproductive - gamete production
Name 2 special types of epithelial cells
Endothelium
Mesothelium
Euchromatic
having chromosomal material that is genetically active and stains lightly with basic dyes
Function of Simple Cuboidal Cells
Secretion
Absorption
Characteristics of Simple Cuboidal Tissue
- Cells tall as they are wide
- Lining kidney tubules, parts of respiratory tract and ducts.
Fibroblast/Fibrocyte
-Most common CT cell
-Prominent nucleus;
-Round or oval in shape
-Euchromatic
Capable of motility
Function of Fibroblast/Fibrocyte
synthesis (secretion) of connective tissue fibers and ground substance
Characteristics of Simple Columnar Epithelial Tissue
- Cells taller than they are wide
- Nuclei are typicall basal and in a row.
- Location: Lining stomach, intestines, parts of respiratory tract, lining of ducts.
-Frequently has microvilli
Function of Simple Columnar Epithelial Tissue
Absorption
Secretion
Characteristics of Stratified squamous epithelium
- multiple layers
- Specialized to resist forces of friction
- Named by the most superficial layer
- Keratinized
- Non-keratinized
Characteristics of Psuedostratified columnar epithelium
- crowded appearance
- Nuclei are in various positions (not in row)
- Simple (all cells contact
the BM)
- Ciliated and Non-ciliated
Found in:
Respiratory tract
Urogenital tract
Characteristics of Transitional epithelium
- Scalloped/cobblestone appearance
- Variation of pseudostratified epithelium (simple)
- Unique property that
accommodates stretching
- All cells contact basement
membrane
Found in:
Urogenital tract
3 Types of Intracellular Junctions
Anchoring junctions
Occluding junctions
Communicating junctions
Basement Membrane
-Separation between the epithelium and connective tissue
Function:
Cell adhesion
Diffusion barrier
Cell growth
Apical Surface Modifications
Microvilli
Cilia
Stereocilia
Microvilli
- Tiny surface projections at the Apical pole
Composition: Glycocalyx
(coating of glycoproteins and other complex sugars)
Function:
Increases surface area
Absorption
Axoneme
– a cylindrical array of microtubules
- 9 “doublets” and two singles centrally located
Dynein arms
force-generating protein present in cilia
CT Fiber Types
-Collagen
-Elastic
Types of Collagen
I, II, III, IV
4 Types of Connective Tissue
Connective tissue proper
Cartilage
Bone
Blood
Collagen Type I
- "Coarse Collagen
- 90% body's collagen
- Skin, bone, tendons, ligaments, & interstitial spaces
- H& E= orange to orange-pink
- Trichrome= blue
- Fibril forming collagen
Collagen Type II
-Fine Collagen
-Cartilage/spinal cord
Collagen Type III
- Synonymous with reticular fibers
- Silver or immunostaining
Origin: Lymphoid organs, bone marrow, visceral organs, skin
- Synthesized by reticular cells, fibroblasts & smooth muscle cells
Collagen Type IV
Location: basement membranes
- Network forming collagen
- Synthesized by epithelium
Fiber (Fibrous) Collagen
- Elasticity & recoil
- stains pale pink
- highly refractile
-Origin: nuchal ligament, arteries, lung
-synthesized by fibroblast, smooth muscle cells, chondroblasts
Ground substance
- Glue between cells and fibers of CT
- Mixture of proteoglycans, glycosaminoglycans, and glycoproteins
- effects morphogenesis, injury, and repair
Stain: Washed out in routine preparations
Connective Tissue Proper
Loose irregular
Dense irregular
Dense regular
Adipose tissue
Function of Mast Cell
-inflammation
-antigenic stimulation
Reticular cells
Location
Shape
Cytoplasm
-Function
-Location: Lymphoid organs
-Shape: Stellate
-Cytoplasm: Basophilic
- "fixed” fibroblasts
- Function: synthesize reticular fibers (type III collagen)
Macrophages
Origin
Cytoplasm
Function
- 2nd most common CT cell
- Origin: blood monocyte
- Cytoplasm; filled with lysosomes & debris
-Function: phagocytic activity & inflammation
Loose irregular
- highly cellular, few fibers
- fibroblast the predominant cell
- soft and pliable
- support and vascular supply for epithelia
- interstitial tissue in most organs
Plasma Cell
Origin
Cytoplasm
Nucleus (characteristic)
Function
- Origin: Derived from B lymphocytes
-Cytoplasm: very basophilic cytoplasm; small cell in general
- Nucleus- Heterochromatic
“wagon wheel”
- Function: Humoral antibody production
Types of cells present in Connective Tissue Proper
Mesenchymal
Fibroblasts
Reticular
Fat
Pericytes
Mast
Macrophages
Plasma cells
Leukocytes
Types of fat cells
-Unilocular
-Multilocular
Mesenchymal cells
Embryonic mesoderm
Undifferentiated
Pluripotent
Euchromatic nucleus
What cell synthesizes type III collagen (reticular fibers)
Reticular cells
Staining characteristic of adipose tissue.
Does not stain in routine H&E
Function of Adipose tissue
- energy
- heat production
Mast cells
-type of CT
-very large cell
-Round nucleus
-Cytoplasm
-filled with large round, pleomorphic granules (heparin & histamine)
Sarco-
Flesh
SARCOLEMMA
plasmalemma (plasma membrane) of a muscle cell
SARCOPLASM
cytoplasm of muscle
SARCOPLASMIC RETICULUM
a form of smooth endoplasmic reticulum, adapted to ion flux/conductance within a muscle cell
myoblast
myofiber precursor; cells that differentiate into mature muscle cell
myofilaments
The filaments of myofibrils constructed from actin and myosin proteins
myofibril
group of muscle myofilaments
myofiber
a single muscle cell, made up of multiple myofibrils, which are in turn made up of myofilaments
Skeletal Muscle
- voluntary
histlogical features
- striated (because it possesses visible “striations” or lines)
- multiple peripherally located nuclei
-nucleiappear spase bc fibers are very large
- myofibers arranged in groups called fascicles, surrounded by connective tissue
Fiber
(myofiber) one cell
- product of multiple fusions of myoblasts during embryonic development
- slightly tapered and blunt at either end; elongated, tubular morphology
Skeletal muscle nuclei (shape)
oval (cigar-shaped) in longitudinal section, round in cross section, with clumped chromatin pattern
Sarcomere
the structural and contractile unit of muscle
"Z” line
centrally located black line in I band
acts to anchor actin filaments
“A” band
- composed of centrally overlapping actin and myosin filaments at the either end of the band, and myosin alone in the center
“I” band
composed of the Z line and the actin filament ends at either pole of two adjacent sarcomeres
“H” band
- composed of myosin only in the center of the sarcomere
“M” line
- center of sarcomere, composed of “tails” of thick myosin filaments
Sarcoplasmic reticulum
Extensive network of tubules (webbing) surrounding/embracing the myofibrils
function as storage units for cations important in contraction
Triad
- at A-I junction
- point at which terminal cisternae are aligned in “twos”, separated by a specialized invagination of the sarcolemma called a T-tubule
- important in the conductance of Ca++ from sarcoplasmic stores across the sarcolemma to the myofibrils
endomysium
CT fibers and matrix surrounding each individual myofiber (muscle cell)
perimysium
– CT fibers and matrix surrounding each individual myofiber (muscle cell)
epimysium
surrounds bundles (groups) of myofibers, call fascicles
myotendinous junction
the CT that surrounds the muscle and its components
is continuous with the CT which anchors the muscle to the bone
tendons
- attach muscle to bone
- dense regular connective tissues
- where tendons attach to bone = regions of transition, fibrocartilage is typically found