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140 Cards in this Set

  • Front
  • Back

What is the genus and species name of the guinea pig?

Genus: Cavia



Species: Cavia porcellus

What are the TPR's of the guinea pig?

T: 99.0 - 103.1


P: 240 - 310


R: ????

What is the gestational period of a guinea pig? What is the average?

59-72 days but the average is 68 days

What is the average weight of a female guinea pig? Male?

•700-900 grams


•900-1200 grams

What is the average litter size of a guinea pig? What is the usual?

1-13 but 2-4 is usual

What are the daily food and water requirements of a guinea pig?

•Clean water BOTTLE should be given daily


•Should be fed a high-quality commercial feed (not rabbit feed b/c of its fiber content)


•Also requires additional Vitamin C

What is a female guinea pig called? A male? Babies?

•Sow


•Boar


•Pups

When do female guinea pigs reach sexual maturity? What about males?

•2 months


•3 months

What is the normal birth weight of pups?

70-100 grams

What is the term for parturition in a guinea pig?

Farrowing

What is the weaning age of pups?


A) 12 days or 180 grams in body weight


B) 7 days or 160 grams in body weight


C) 21 days or 180 grams in body weight


D) 13 days or 175 grams in body weight

C) 21 days or 180 grams in body weight

What is the length of estrous cycle in guinea pigs?

15-17 days

Name the 6 guinea pig breeds

•English


•Peruvian


•Abyssinian


•Silkie


•Teddy


•American Crested Cavy

What are the 3 primary breeds of guinea pigs?

•English


•Peruvian


•Abyssinian

What are the 3 less common breeds of guinea pigs?

•Silkie


•Teddy


•American Crested Cavy

What breed of guinea pig is used in research? Name two within that breed

•English


•Duncan-Hartley, & Hartley

Who has the larger anogenital distance? Male guinea pigs or female?

Male

Female guinea pigs must be bred before the age of _______.


A) 6 months


B) 3 years


C) 4 months


D) 2 years



What occurs if they are not bred before that age?

•A) 6 months


•The pelvic symphysis fuses

What is the medical term for a guinea pig that presents a copulatory behavior of arching the back and swaying the hindquarters much like a female cat in heat?

Lordosis

Guinea pig pups are born ___________, _________, and ________________.

•Eyes open


•Fully haired


•Capable of eating solid food within hours

T/F: Guinea pig ears are hairless

True

Guinea pigs have _ digits on hind limbs and _ digits on forelimbs

3 digits on hind limbs and 4 digits on forelimbs

In the thorax of the guinea pig, the right lung is composed of _ lobes while the left lung is composed of _ lobes

right lung composed of 4 lobes, left lung composed of 3 lobes

Guinea pigs have 4 pairs of salivary glands, what are they?

•Parotid


•Mandibular


•Sublingual


•Molar

Guinea pigs have ______ distinct vocal patterns


A) 10


B) 13


C) 9


D) 11

D) 11

How is the dentition of a guinea pig different from other rodents?

1 premolar is present in each quadrant

In guinea pigs, what is the diastema?

The small gap between the molars and premolars

What is the palatal ostium in the guinea pig? What is significant about this feature?

•A hole in the soft palate that is the opening between the oropharynx and the rest of the pharynx


•Makes endotracheal intubation difficult because it is narrow

What is unique about the abdomen of the guinea pig?


What glands are present around the anus? What are they used for?

•Liver is divided into 6 lobes


•Sebaceous glands, used for marking

What is distinct about the male guinea pig reproductive system? (2)

•Os penis is present


•Testes remain in open inguinal canal throughout it's entire life

What are some characteristics of guinea pig urine?

•Urine is alkaline, highly crystalline


•Color usually appears creamy yellow or white

How can gender be determined in guinea pigs?

•Females have a Y-shaped depression in perineal area


•Males have scrotal pouch and testes

T/F: Ovulation in guinea pigs is spontaneous with estrus lasting 5 to 13 hours

False - ovulation IS spontaneous but estrus lasts between 6-11 hours

Approximately how long after parturition does postpartum estrus occur in guinea pigs?

2-10 hours

What order are guinea pigs in?

Rodentia

T/F: Smaller litters of guinea pigs have shorter gestation periods and larger litters of guinea pigs have longer gestation periods

False - Smaller litters have longer gestation periods while larger litters have shorter gestation periods

T/F: A copulatory plug made up boar secretions is present to confirm mating of guinea pigs

True

Guinea pig mothers-to-be ______ nest prior to farrowing, therefore, pending parturition begins by separation of the fused pelvic bones.



A) Do


B)Do not

B) Do not

Pups should remain with the sow until at least ____ days postpartum


A) 5


B) 9


C) 6


D) 7

A) 5

For the pup's first week, mothers will stimulate _________ and __________

Urination and defecation

What guinea pig breed has short, smooth, straight hair?

English

What guinea pig breed has long and fine hair?

Peruvian

What guinea pig breed has short, coarse hair that grows in whorls or rosettes?

Abyssinian

What guinea pig breed has long hair that does not cover the face or part down the back?

Silkies

Guinea pig breeding programs may use _________ or __________ systems

Intensive or nonintensive

Which system uses the postpartum estrus period?

Intensive

The sow lactates for approximately ____ weeks, at which time the pups should be fully weaned.


A) 6


B) 3
C) 2
D) 5

B) 3

What guinea pig breed has short hair that is in a single whorl of contrasting color on the forehead?

American Crested Cavy

What guinea pig breed has short, coarse hair that has kinked hair shafts without ridges or rosettes?

Teddy

T/F: Polygamous mating systems involve a single boar to be housed with one to ten sows

True

Describe nonintensive systems

Sows are removed from the breeding group when pregnant and are not re-bred until after the young are weaned

What is the guinea pigs' natural habitat? (4)

•Temperate forests, rainforests, & grasslands


•Social animals that live in groups


•Active for the majority of a 24 hour period


•Use deserted burrows by other animals for environmental protection

What may occur when guinea pigs become frightened?

may become immobile for up to 20 minutes

What are the 6 methods of identification in guinea pigs?

•Cage cards


•Ear notching


•Ear tags


•Tattooing


•Microchips


•Markers/dyes

Guinea pigs have a strong need for a dietary source of Vitamin ___ to prevent scurvy.


This can be supplemented in the diet by what 3 things?

•C


•Water supplement, fresh vegetables (cabbage or kale), or in feed

___________ is an important part of nutrition and guinea pigs can lose weight if prevented

Coprophagia

Improper handling of guinea pigs can cause what 3 things?

•Bruised lungs


•Diaphragmatic hernia


•Thoracic compression

What are the two types of routes for medication administration in guinea pigs?

•Injections (IM, IP, IV, SQ)


•Oral

Where can IM injections be administered in the guinea pig?

Quads & SM/ST

Where can IV injections be administered in guinea pigs? (6)

•Lateral metatarsal


•Penile


•Lingual


•Saphenous


•Cephalic


•Marginal ear veins

_____mL of sugar or syrup can be added to _____ liter(s) of drinking water to unpalatable medications

5mL, 1 liter

Where can small blood samples be collected from in the guinea pig? (3)

•Toenail clip


•Saphenous vein


•Cehalic vein

Where can up to 8mL of blood be collected from in the guinea pig? (3)

•Jugular


•Femoral artery


•Cranial vena cava

What is the whole blood volume in rabbits?

55-70 mL/kg

What is the second pair of of incisors termed in rabbits?

Wolf teeth/peg teeth

How often do rabbit teeth need to be trimmed?

Every 6-8 weeks

What organ serves as a thermoregulator in rabbits?

Ears

T/F: Rabbits CAN vomit

False

What are cecotrophs?

Night feces

In rabbits, who has a larger anogenital distance, males or females?

Males

Describe the breeding colonies for rabbits

1 buck to 10-20 does

How long after coitus does ovulation occur in the rabbit?

Approx. 10 hours

When does weaning occur in rabbits?

5-8 weeks

How do rabbits communicate?

Through scent, touch, and thump cues

Rabbits cannot tolerate temperatures below _____ and above ______.


Room temperature should be maintained in the upper _______

•Below 39 and above 82


•60's

What are the daily food and water requirements for rabbits?

Food: 50g/kg



Water: 50-150 mL/kg

Where is the pulse taken in a rabbit?

Femoral artery

Rabbit teeth can grow up to ________ per year

5 inches

What prohibits vomiting in rabbits?

Limiting ridge at junction of esophagus & stomach

What are the injection sites in rabbits?

•SQ


•IV - marginal ear vein


•IM - epaxial, SM/ST, quads


•ID

What are the blood collection sites in rabbits?

•Cephalic


•Central auricular artery


•Saphenous


•Jugular


•Marginal ear vein

Where can you not place a catheter in a rabbit?

Ear veins b/c they're too delicate, but you CAN place it in cephalic, saphenous or jugular

What is the genus and species name of rats?

•Rattus



•Rattus norvegicus (pet or lab rat), Rattus rattus (wild rat)

Which have longer tails, male or female rats?

Males

What are the functions of the rat tail? (2)

•Balance


•Thermoregulator

What is special about the feet pads of rats?

Contain the only sweat glands of the body

What is the weight of male rats? Females?

•Males: 267-500 g


•Females: 225-325g

What are the characteristics of newborn rats? (3)

•Born hairless


•Deaf


•Blind

What is the gestation length of a rat?

21-23 days

What is the act of parturition in rats?


What is the avg rat litter size?


What are baby rats called?

•Rearing


•6-13


•Pups

What is the weaning age of rats?

21 days

Rat forelimbs contain __ digits while hindlimbs contain ___

4, 5

When do female rats reach sexual maturity? Males?

•37-67 days


•40-75 days

What is significant about the rat reproduction?


What is estrus cycle length?


Postpartum estrus occurs ___-____ hours after parturition

•Continuously polyestrous


•4-5 days


•20-24 hours

Give the TPR's of the rat

T: 99.9


P: 313-493 bpm


R: 71-146 bpm

Why are rats the best choice for research? (6)

•Prolific - Incr. breeding


•Easily housed


•Easily handled


•Inexpensive


•Adapt to most environmental changes


•Dependable breeders

What is the Harderian gland in rats?


What is its function? What causes this to occur?

•Lacrimal gland of the eye


•Secretes porphyrin, red-pigmented substance (red tears); will increase when rat is ill or stressed

What is the term for a rat that is ill or stressed?

chromodacryorrhea

T/F: Rat nares can close under water

True

T/F: Rats do not have tonsils

True

How many pairs of salivary glands do rats have?

3

What is stored around the neck region of the rat?


What does this do? (2)

•Brown fat


•Provides increased energy storage & is a metabolic regulator

T/F: Rats can vomit and they do have a gallbladder

False- they CANNOT vomit and they DO NOT have a gallbladder

When does breeding occur for rats?

Generally, at night

Rat copulatory plug persists for ___ - ____ hours post mating due to semen mixing w/ vaginal secretions


Why is this used?

•12 - 24 hours


•To confirm mating (same as guinea pigs)

Newborn rat ears open between ___ - ___ days.


Eyes open between ___ - ____ days.


They are fully haired by __ - ____ days.


Begin eating solid food by the end of the ______ week

•3-5 days


•7-14 days


•7-10 days


•Second

What are the two mating systems for rats?


Describe each

•Monogamous - one female to one male


•Polygamous - two or more females to one male

What are the two breeding systems for rats?


What are the adv. & disadv. of each?

•Intensive


Adv. polygamous: least space, post-partum estrus


Disadv. polygamous: Incr. in incidence of fighting, injury to offspring, & stress to females (pregnant or nursing)


•Non-intensive


Adv.: decr. in fighting, stress, & injury to offspring


Disadv: Decr. in offspring

What is the daily consumption of rat feed?


How should they be fed?

•5g/100g Body Weight/day


•Generally fed ad lib

What are the 2 types of genetics in rats?

Stocks & Strains

What is stock genetics in rats?

Randomly bred - AKA "Outbred"


Similar characteristics but not genetically identical

What are commonly used outbred stocks of rats? (3)

•Sprague-Dawley (SD)


•Long-Evans (LE)


•Wistar (WI)

What is strain genetics in rats?


Genetically heterozygous or homozygous?

•Inbred -> considered this when at least 20 gens of bro-sis or parent-offspring matings occur


•Homozygous

Why do some inbreeding fails occur in rats?

Occur due to "inbreeding depression"

What are some commonly used inbred strains of rats? (5)

•Albany (ALB) - in mammary tumor studies


•Spontaneous Hypertensive Rat (SHR) - in HBP studies


•Brown (BN) - in leukemia studies


•Buffalo (BUF) - in autoimmune disease studies


•Fisher344 - in esophageal & bladder carcinoma

What is the term for a group of rats?

A mischief

T/F: Rats are not colorblind

False - they ARE colorblind

What is coisogenic?


Congenic?

•Genetic mutation in existing strains


•Mutation that arises in one strain and is transferred to another

What is athymic?

Nude

What is hybrid?

•Mating between two inbred strains

What is transgenic?

Removing a specific DNA from one strain and inserting them into an ovum.


ex: Huntington's disease, Alzheimer's

What is the lowest certificate of vet techs?


What agency is used to get certified?

•ALAT


•AALAS

What agency must approve the experimental design if live animals are used? They also approve all animals that are being used.

IACUC (Institutional Animal Care & Use Committee)

Should the surgery room be under +ve or -ve pressure?

Positive

What is the principle federal statute governing the safe handling, transport & safe use of animals?

Animal Welfare Act

The _________is responsible or all aspects of animal use, education, health, & compliance w/ all laws & regulations

IACUC

The _______ enforces the AWA

USDA

The _________ is the federal govt. agency that administers laws that protect human health & environment

EPA (Environmental Protection Agency)

__________ is a private non-profit organization that promotes the humane treatment of animals in science through a voluntary accreditation program

AAALC (Assoc. for Assessment & Accreditation of Lab Animal Care)

What is a conventional facility?

Animals rooms & support areas that have single doors that open into a central corridor

What is a double corridor facility?

"Clean/dirty" - rooms and areas have 2 doors entering the clean corridor and the other to the dirty

What is a barrier facility?

Same as double but personnel must shower before entering animal rooms

What are containment facilities?

Personnel must shower before entering and when they leave

What cage system is used to measure urine & feces?

Metabolism

_____________ animals have undefined microflora. (demonstrated to be free of of certain pathogens, but not free of unspecified ones)

SPF (Specific Pathogen-free)

What does brown fat in the neck do?

Metabolic regulation

Rat parturition is termed ________

Rearing

What is the dental formula for a rabbit?

2(I2/1C0/0P3/2M3/3)

What is applied research?

The use of existing knowledge for solving a biomedical problem like developing vaccines

What is clinical research?

Build knowledge gained in basic & applied research


always conducted on live animals & humans