Vesicular/bullous Lesions

Front 1

A neonate presents with extensive blisters developing from a rash and a positive Nikolsky sign at the stratum granulosum.

Back 1

Staphylococcal Scalded Skin Syndrome / Ritter's Disease

Front 2

Similar to Staphylococcal Scalded Skin Syndrome, however affects older patients due to drug use and cleavage is between the epidermis and dermis.

Back 2

Toxic Epidermal Necrolysis

Front 3

A 6 year old, non vaccinated male presents with macules, papulovesicles, and crusted erosions on the trunk.
Key words: centripetal pattern; Dewdrops on rose petals; all stages of lesions.

Back 3

Chickenpox/Varicella

Front 4

What is the etiology of Chickenpox?

Back 4

Human Herpesvirus 3

Front 5

What are the complications of Chickenpox?

Back 5

1) Reye's syndrome (fatty liver with encephalopathy)
2) Zoster (singles) - peripheral neuritis
3) More severe with age

Front 6

How do you diagnose Chickenpox? Therapy? Contraindicated?
Prevention?

Back 6

Positive Tzanck test for the presence of giant cells with nuclear inclusions.
Therapy: Acyclovir if severe.
Contraindicated: Salicylates
Prevention: Varivax, live attenuated virus

Front 7

A child presents with fever, arthralgias, and sore throat with vesicular/ulcerating lesions in and around the mouth, palms/soles.

Back 7

Hand-Foot-and-Mouth

Front 8

Etiology of Hand-Foot-and-Mouth?

Back 8

Coxsackie

Front 9

A child presents with fever, headache, anorexia, and painful neck and extremities. Vesicular lesions on the tonsils or soft palate appear and ulcerate over the next 2 days.

Back 9

Herpangina

Front 10

An adult presents with malaise and recurrent tender vesicular (Tzanck test positive) lesions around the mouth or on the genitalia.

Back 10

Herpes Skin Infections

Front 11

Types of Herpes Skin Infections

Back 11

Cold Sores - mouth
Gingivostomatitis - gingiva, teeth
Balantis - penis
Vulvovaginitis - vagina
Keratoconjunctivitis - eye
Gladiatorum - from wrestling mats

Front 12

Etiology of Herpes Skin Infections?
Manifestations?
Epidemiology?

Back 12

Herpes Simplex type 1 or 2
Grouped vesicles on an erythamatous plaque
Transmitted by saliva, contact with sores or kissing...RECURRENCES precipitated by STRESS

Front 13

Therapy of Herpes Skin Infections?

Back 13

Acyclovir

Front 14

A 70 year old female cancer patient experiences severe, left-sided superficial trunk pain preceding vesicular eruption of an anterior chest dermatome.

Back 14

Herpes Zoster

Front 15

Etiology of Herpes Zoster?
Epidemiology?
Pathology?

Back 15

Etiology: HHV 3 (VZV)
Epidemiology: Incidence increases with age (50-80) and immunosuppressed
Pathology: Inflammation of sensory root ganglia and skin of dermatome, which is hyperesthetic and severely painful. Vesicular eruptions occur on trunk where chickenpox was most severe and are unilateral.

Front 16

THerapy of Herpes Zoster?

Back 16

Acyclovir

Front 17

Following a fever, a child presents with widespread vesicular lesions of one type. The rash is centrifugal and macular. Lesions are most numerous on the extremities and progress rapidly to severe ulcerations with scabs.

Back 17

Smallpox (Variola)

Front 18

Similar to Smallpox, but mild and involves lymphadenopathy?

Back 18

Monkeypox

Front 19

Epidemiology of Smallpox?
Diagnosis?
Therapy?

Back 19

Epidemiology: Select agent (A)
Diagnosis: Guarnieri Bodies
Therapy: Cidovir