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19 Cards in this Set
- Front
- Back
A neonate presents with extensive blisters developing from a rash and a positive Nikolsky sign at the stratum granulosum.
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Staphylococcal Scalded Skin Syndrome / Ritter's Disease
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Similar to Staphylococcal Scalded Skin Syndrome, however affects older patients due to drug use and cleavage is between the epidermis and dermis.
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Toxic Epidermal Necrolysis
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A 6 year old, non vaccinated male presents with macules, papulovesicles, and crusted erosions on the trunk.
Key words: centripetal pattern; Dewdrops on rose petals; all stages of lesions. |
Chickenpox/Varicella
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What is the etiology of Chickenpox?
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Human Herpesvirus 3
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What are the complications of Chickenpox?
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1) Reye's syndrome (fatty liver with encephalopathy)
2) Zoster (singles) - peripheral neuritis 3) More severe with age |
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How do you diagnose Chickenpox? Therapy? Contraindicated?
Prevention? |
Positive Tzanck test for the presence of giant cells with nuclear inclusions.
Therapy: Acyclovir if severe. Contraindicated: Salicylates Prevention: Varivax, live attenuated virus |
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A child presents with fever, arthralgias, and sore throat with vesicular/ulcerating lesions in and around the mouth, palms/soles.
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Hand-Foot-and-Mouth
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Etiology of Hand-Foot-and-Mouth?
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Coxsackie
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A child presents with fever, headache, anorexia, and painful neck and extremities. Vesicular lesions on the tonsils or soft palate appear and ulcerate over the next 2 days.
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Herpangina
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An adult presents with malaise and recurrent tender vesicular (Tzanck test positive) lesions around the mouth or on the genitalia.
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Herpes Skin Infections
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Types of Herpes Skin Infections
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Cold Sores - mouth
Gingivostomatitis - gingiva, teeth Balantis - penis Vulvovaginitis - vagina Keratoconjunctivitis - eye Gladiatorum - from wrestling mats |
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Etiology of Herpes Skin Infections?
Manifestations? Epidemiology? |
Herpes Simplex type 1 or 2
Grouped vesicles on an erythamatous plaque Transmitted by saliva, contact with sores or kissing...RECURRENCES precipitated by STRESS |
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Therapy of Herpes Skin Infections?
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Acyclovir
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A 70 year old female cancer patient experiences severe, left-sided superficial trunk pain preceding vesicular eruption of an anterior chest dermatome.
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Herpes Zoster
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Etiology of Herpes Zoster?
Epidemiology? Pathology? |
Etiology: HHV 3 (VZV)
Epidemiology: Incidence increases with age (50-80) and immunosuppressed Pathology: Inflammation of sensory root ganglia and skin of dermatome, which is hyperesthetic and severely painful. Vesicular eruptions occur on trunk where chickenpox was most severe and are unilateral. |
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THerapy of Herpes Zoster?
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Acyclovir
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Following a fever, a child presents with widespread vesicular lesions of one type. The rash is centrifugal and macular. Lesions are most numerous on the extremities and progress rapidly to severe ulcerations with scabs.
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Smallpox (Variola)
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Similar to Smallpox, but mild and involves lymphadenopathy?
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Monkeypox
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Epidemiology of Smallpox?
Diagnosis? Therapy? |
Epidemiology: Select agent (A)
Diagnosis: Guarnieri Bodies Therapy: Cidovir |