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6 Cards in this Set

  • Front
  • Back

Five causes of hypoxemia

1. Low inspired PiO2


2. Hypo ventilation


These: the A-a gradient will be normal bc the lungs are normal



3. Diffusion limitations


4. Shunt


5. V/Q imbalance


There are abnormalities in the A-a gradient so it is will be increased

V/Q of...


Dead space


Normal lung


V/Q imbalance


Shunt

V/Q of...


Dead space infinity


Normal lung 1


V/Q imbalance <1


Shunt 0

A-a gradient

Normal room air at sea level PA02=100mmHg



Normal room air at sea level PaO2=95



Because of physiologic shunts, normally is a grading if 0-10mmHg

Oxygen carry content formula

CaO2 (content)=(Hb x SaO2 x 1.34) + (PaO2 x 0.003); if equal to a 100% than SaO2 is O3 carrying capacity

Oxygen Deelivery

DO2=CaO2 x CO x 10

O2 Hb dissociation curve: 4 influences

Right shift= less uptake at the alveolar level but greater degree of unloading at tissue level (example is exercising)



Right shift if


Decrease in pH


Increased PaCO2 (Bohr effect)


Increase in 2,3 DPG


Increase in temperature