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7 Cards in this Set
- Front
- Back
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Nitroglycerin
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Converted into NO in tissues (preload reduction)
Onset: 2-4 mins Duration: 30-60min Side effects: Tolerance, reflex tach Orthostatic hypotension |
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Isosorbide Dinitrate
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Converted into NO in tissues( Preload reduction)
Onset 2-4min Duration 2-4hrs. Side effects: Tolerance, reflex tach, Orthostatic hypotension |
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Verapamil
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Type I Ca2+ channel blocker
-myocardial and vascular effects Reduce O2 consumption by decreasing afteload and HR Major Side effects: Cardiodepression |
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Diltiazem
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Type I Ca2+ channel blocker
-myocardial and vascular effects Reduce O2 consumption by decreasing afteload and HR Few major side effects |
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Nifedipine
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Type 2 Ca2+ channel blocker
-predominantly vascular effects Vasodilate, INCREASE HR, increase contractility Major SE: Hypotension, Edema |
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Metoprolol
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Beta-Blocker
Decrease myocardial O2 demand *Give to people w/ previous MI Use diuretics in combo w/ B-blocker |
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Sildenafil
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Phosphodiesterase 5 inhibitor
Low oral bioavailability CYP3A4 hepatic metabolism t1/2= 4 hrs. |
