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39 Cards in this Set

  • Front
  • Back
List three factors that increase MAC
hypernatermia
hyperthermia
increased levels of CNS NTs
What two electrolyte imbalances will cause MAC to decrease
hypercalcemia
hyponatremia
When are the MAC values highest? What is the exception to this?
infants 1-6 months
Sevo - first month
What is the acceptable level of N20? VA?
25 ppm
2 ppm
The use of barbiturates is absolutely contraindicated in which two disease?
porphyria
status asthmaticus
Rank the opioids from most to least lipid soluble
sufentanil
fentanyl
alfentanil
demerol
remi
morphine
In what two ways do opioids produce spinal anesthesia
presynaptically- decrease release of sub P
postsynaptically- decrease activity of neurons in the spinothalamic tracts
How does electrical stimulation of the periventricular and periaqueductal gray produce analgesia
produces spinal analgesia via the dorsolateral tract
Do opioids inhibit HPV
no
Rank the opioid from most to least potent
sufentanil
remi
fent
alf
morph
demerol
What are the IV and IM doses of ketamine
1.5 mg/kg
7 mg/kg
What additive is found in etomidate
propylene glycol
Which IV anesthetic agent is a single isomer
etomidate
Do opioids inhibit HPV
no
Rank the opioid from most to least potent
sufentanil
remi
fent
alf
morph
demerol
What are the IV and IM doses of ketamine
1.5 mg/kg
7 mg/kg
What additive is found in etomidate
propylene glycol
Which IV anesthetic agent is a single isomer
etomidate
Where is propofol metabolized?
liver
lungs
What agents potentiate amide toxicity
VA
propranolol
cimetidine
What four conditions decrease plasma cholinesterase
pregnancy
liver disease
first 6 months of life
atypical plasma cholinesterase
Which LA are chiral
bupiv
levobupiv
mepiv
ropiv
Which local anesthetics are pure S entantomers
levobupiv
ropiv
Which 2 LA are racemic mixtures
bupiv
mepiv
What is the dose for epi when used with LA
3-5 mcg/kg
Which 2 LA are racemic mixtures
bupiv
mepiv
What are the 2 classifications of ND NMB and how do you distinguish the two
benzylisoquinoliniums and steroid derivatives

steroids end in -curonium
What are four drugs that potentiate ND NMB
mag
aminoglycosides (neomycin, streptomycin)
dantrolene
Ca channel blockers
What group of antibiotics most enhance NMB? How?
polymixins

postsynaptically
What is the dose for epi when used with LA
3-5 mcg/kg
What are the 2 classifications of ND NMB and how do you distinguish the two
benzylisoquinoliniums and steroid derivatives

steroids end in -curonium
What are four drugs that potentiate ND NMB
mag
aminoglycosides (neomycin, streptomycin)
dantrolene
Ca channel blockers
What group of antibiotics most enhance NMB? How?
polymixins

postsynaptically
How does Lasix interact with NMB?
Lasix decreases cAMP thereby decreasing calcium -> AcH release thereby enhancing NMB
What are 6 metabolic/electrolyte disturbances that enhance NMB
resp acidosis
met alkalosis
hypothermia
hypercalcemia
hypokalemia
hypermagnesemia
How does phenytoin react with NMB?
decreases ND NMB
What affect does carbamazepine have on ND NMB?
decreases ND NMB
How does succs given before ND NMB enhance the action of NDNMB
contributes to phase 2 blockade
How is cholinergic syndrome diagnoses?
edrophonium is administered.

worse = cholinergic crisis
better = myasthenic crisis