Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
79 Cards in this Set
- Front
- Back
Pt with neuro deficits + acute renal failure + hemolytic anemia and thrombocytopenia
Most likely dx? Tx? |
TTP-HUS
Tx: plasma exchange (plasmaharesis) Plt transfusion is CONTRAINDICATED |
|
Pt with chronic headaches and painless hematuria
Most likely dx? |
Analgesic Nephropathy
|
|
Pt with palpable purpura + proteinuria + hematuria + decreased complement levels
Most likely dx? Next step? |
Mixed essential cryoglobulinemia
Next step: Test for HCV (most have underlying HCV) |
|
Gram negative rods that cause pneumonia?
At risk pts? Tx? |
- Pseudomonas
- intubated patients (nosocomial), exposure to contaminated water faucets, pools, plant products - 4th gen cephalosporin (cefepime), Cipro, aminoglycosides, Pip-tazo |
|
mobile cavitary mass
|
Aspergilloma
|
|
stellate purpura with gunmental grey seen in?
|
meningococcemia
|
|
endometritis tx (abx)
|
clinda + gent
|
|
hearing loss + elevated alk phos
likely dx? |
Paget's
- elevated alk phos but normal Ca and Phos |
|
neuro deficits in subarachnoid hemorrhage
|
no focal neuro deficits!
|
|
most common site of hypertensive hemorrhage (hemorrhagic stroke from htn)
|
basal ganglia - particularly putamen
|
|
normal liver span
|
6-12 cm in midclavicular line
|
|
antiemetic that causes extrapyramidal symptoms and neuroleptic malignant syndrome
tx? |
Metaclopramide
Tx: D/C med and give Diphenhydramine/ or Benztropine |
|
ear fullness is particularly suggestive of...?
|
meniere's (inner ear disease)
|
|
Kaposi sarcoma caused by...?
|
Human Herpesvirus 8 (HHV 8)
|
|
recurrent oral ulcers, recurrent genital ulcers, vision problems (uveitis), painful skin ulcers (nodules)
dx? tx? complication? |
- Behcet's syndrome
- steroids only for symptomatic relief - progresses to dementia/blindness |
|
diarrhea after ingestion of seafood.
bug? |
Vibrio parahaemolyticus
|
|
syphilis tx if allergic to PCN
|
PO Azithromycin x1
or 2weeks or PO Doxycyline |
|
JAK2 mutation found in
|
Polycythemia vera
|
|
RMSF tx?
RMSF tx in pregnant? |
Doxycycline
If pregnant -- Chloramphenicol |
|
Legionnaire's tx
|
Erythromycin
|
|
intravascular hemolysis labs
|
elevated LDH and bili
|
|
intravascular hemolysis + vein thrombosis
dx? |
Paroxysmal nocturnal hemoglobinuria
|
|
Pamidronate - what is it and what is it used for?
|
bisphosphonate, for long-term treatment of hypercalcemia of malignancy
|
|
salicylate intoxication symptoms
|
tinnitus, n/v, fever, AMS, acidosis
|
|
serotonin syndrome symptoms
|
tachycardia, diaphoresis, dilated pupils, hyperthermia
|
|
vertical nystagmus - intoxication of?
horizontal nystagmus - intoxication of? |
vertical - PCP (phencyclidine)
horizontal - PCP, phenytoin |
|
theophylline toxicity symptoms
|
n/v, hypotension, seizures, hyperthermia, arrhythmias
|
|
diphenhydramine intoxication symptoms
tx? |
drowsiness, confusion, ataxia, blurry vision, pupil dilation, dry mouth, urinary retention)
(i.e. anti-cholinergic effects) tx: cholinesterase inhibitor: physostigmine |
|
+Prussian blue = meaning?
|
indicates hemosiderin = hemolysis
|
|
chondrocalcinosis seen in?
|
pseudogout
|
|
COX-2 mechanism, advantages, risks, example
|
mech: selective cox-2 inhibitor
adv: no GI effects, no hemostatsis effects risks: heart disease ex: Celecoxib |
|
tx for malignant otitis externa
|
cipro
|
|
type of lung CA associated with SIADH
|
small cell CA
|
|
EARLY side effect of levodopa/carbidopa
|
hallucinations, confusion, somnolence
|
|
LATE side effects of levodopa/carbidopa (>5-10years)
|
involuntary movements: dyskinesia, dystonia
|
|
Livedo reticularis side effect of which rx?
|
amantidine
|
|
If null value is INSIDE the CI --> significant or not?
If null value is OUTSIDE the CI --> significant or not |
If inside --> NOT significant
if outside --> Significant |
|
amoxicillin coverage
|
gram-positives, HELPSS (H. flu, E. coli, Listeria, Proteus, Salmonella, Shigella)
|
|
tachy-brady sinusoidal fetal tracing dx?
|
ruptured fetal umbilical vessel
|
|
permanent dilation of bronchi
dx? how to dx? |
bronchiectasis
- high-res CT |
|
Neuroleptic Malignant Syndrome tx? (Name three, mechanism)
|
Dantrolene (muscle relaxant) - 1st line
Bropmocriptine (dopamine agonist) Amantidine (antiviral with dopaminergic properties) |
|
B12 vs folate deficiency --> labs?
|
both have increased homocysteine
only b12 deficiency has elevated methylmalonic acid |
|
patients who need B6 supplement
|
TB pts treated with INH
|
|
B6 deficiency symptoms
|
peripheral neuropathy, seizures, sideroblastic anemia
|
|
bug in infective endocarditis in pt with prosthetic valve
|
Staph epidermidis
|
|
bug in infective endocarditis in pt with diseased valve (subacute)
|
Strep viridans
|
|
most common CA from asbestosis
|
bronchogenic carcinoma
(note: asbestosis is the only RF for mesothelioma, but bronchogenic carcinoma is the most common lung CA from asbestosis) |
|
intox with ? lead to prolonged QRS
|
TCAs
|
|
TRAP stain for?
|
hairy cell leukemia (TRAP the HAIRy animal)
|
|
ok to breastfeed with hepatitis- Y/N?
|
Yes
|
|
cushing's abnormal electrolyte
|
hypokalemia
(cushings: elev cortisol -> elev aldo -> Na reabsorption and K wasting -> hypokalemia) |
|
femoral bowing dx
|
Paget's
|
|
severe wheezing after taking NSAID or ASA
dx? other symptoms and findings? |
Aspirin exacerbated resp dz
symptoms: wheezing, recurrent nasal discharge, recurrent nasal congestion, NASAL POLYPS -> bland taste |
|
nosebleed during pregnancy. dx?
|
pyogenic granuloma
|
|
bug in UTI with long indwelling catheter
|
Proteus -> very basic urine pH
|
|
electrolyte abnormality in subarachnoid hemorrhage
|
cerebral salt wasting -> hyponatremia
|
|
COPD vs emphysema (DLCO and slang)
|
COPD = blue bloater, normal DLCO
Emphysema = pink puffer, decreased DLCO |
|
ards - resp alkalosis or acidosis?
|
resp alkalosis (decreased O2 transfer, decreased CO2 due to decreased ventilation)
|
|
Decreased leukocyte alk phos seen in?
|
1. CML
2. PNH 3. Hypophosphatemia |
|
Positive Alpha-naphthyl esterase test
|
acute monocytic leukemia
|
|
+PAS stain
+PAS reaction |
Whipple's disease
lymphoblasts |
|
name aminoglycosides.
coverage toxic effects? |
Gentamycin, Neomycin, Amikacin, Tobramycin, Streptomycin
covers for Gram-negative rods (including pseudomonas) causes nephrotoxicity and ototoxicity, teratogenic |
|
palpable bilateral abdominal masses + hematuria + HTN + headaches
dx? common complication? |
ADPKD
- intracranial berry aneurysm |
|
trastuzumab aka?
complication/SE? |
Herceptin
cardiotoxic -> need Echo before starting |
|
location of a purely sensory stroke
|
thalamus (VPL nucleus)
|
|
location of purely motor stroke
|
internal capsule
|
|
vaginismus tx
|
kegel and gradual dilation/desensitization with fingers, dilators, etc.
|
|
cat scratch tx
|
po azithromycin
|
|
tx for primary biliary cirrhosis
|
Ursodeoxycholic acid - choice; slows dz progression
methotrexate and colchicine with some benefit liver transplant for advanced dz and the only definitive tx (7-10 yr survival without transplant) |
|
corn-based diet typically deficient in _?
symptoms? |
niacin deficiency
- pellagra: diarrhea, dermatitis, dementia, (and death) |
|
tamoxifen - increased risk for which type of CA
|
endometrial CA
|
|
toxoplasmosis in HIV - tx?
|
sulfadiazine + pyrimethamine
|
|
cause of painless hematuria in sickle cell patients
|
papillary ischemia
|
|
describe TBG and thyroid hormone changes in pregnancy
|
increase in estrogen in pregnancy causes increase in TBG -> so increased TOTAL T3 and T4 (TBG binds most of the thyroid hormones) but FREE T3,4 remain normal
|
|
chalazion tx
vs hordeolum tx |
chalazion - incision and curettage
hordeoulum - warm compress, I&d if doesnt resolve in 48hrs |
|
uti in indwelling foley pts. bug?
|
proteus - very basic urine.
klebsiella and candida also common - but urine not alkaline. |
|
HOCM pattern of inheritance
|
AD
|
|
osteomyelitis in kids - bugs
|
S. aureus
|
|
Increased leukocyte alk phos
|
Leukomoid reaction
vs decreased leukocyte phos in CML |