Usmleworld Poisoning

Front 1

antidotes for anticholinesterase toxicity (e.g. organophosphates)

Back 1

atropine
pralidoxime

Front 2

mechanism of mortality in TCA overdose

treatment of TCA overdose

Back 2

TCA-induced hypotension

secure ABCs, then give sodium bicarb

Front 3

treatment of alcohol withdrawal

Back 3

lorazepam
diazepam
chlordiazepoxide

Front 4

Signs and Sx of methanol intoxication

Back 4

h/n/v
optic disc hyperemia
anion gap metabolic acidosis

Front 5

distinguish between methanol and ethylene glycol poisoning

Back 5

methanol damages eyes

ethylene glycol damages kidneys

Front 6

TCA overdose signs and Sx

Back 6

hyperthermia
seizures
hypotension
anticholinergic effects

important! TCA overdose causes QRS widening and risk of ventricular arrhythmia!

Front 7

phases of iron intoxication

what serum level is toxic?

Back 7

GI phase (30 min)
latent phase (6-24 hrs)
shock, metabolic acidosis (6-72 hrs)
hepatotoxicity (12-96 hrs)
bowel obstruction 2/2 mucosal scarring (weeks)

>350 mcg/mL

Front 8

treatment of acute iron poisoning

treatment of acute lead poisoning

Back 8

deferoxamine

succimer for mild-mod
EDTA for mod-severe

Front 9

signs and Sx of benzodiazepine intoxication

Back 9

slurred speech
unsteady gait
drowsiness

pupil sizes normal, mild respiratory depression

Front 10

treatment for overdose of anticholinergic?

Back 10

physostigmine, a cholinesterase inhibitor

Front 11

etiology of torsades de pointes

treatment of torsades de pointes

Back 11

seen in setting of long QT interval (familial LQT syndrome, hypomagnesemia, TCA intox, amiodarone and sotalol intox, moxiflox and fluconazole intox)

cessation of offending agent + magnesium sulfate

Front 12

treatment of ethylene glycol poisoning

Back 12

fomepizole or ethanol to bind alcohol dehydrogenase

Front 13

treatment of beta-blocker overdose

Back 13

atropine + IV fluids

glucagon if unsuccessful

Front 14

fluphenazine (typical antipsychotic) unusual side effect

Back 14

hypothermia by inhibiting body's shiver mechanism

Front 15

options for NMS if dantrolene not available

Back 15

bromocriptine
amantadine

Front 16

treatment of PCP intoxication

Back 16

benzos

Front 17

time before serum acetaminophen is useful in predicting hepatotoxicity

Back 17

4 hrs (treat with activated charcoal before 4 hours)

administer NAC within 8 hours

Front 18

treatment organophosphate poisoning

Back 18

atropine

organiophosphate poisoning inactivates acetylcholinesterase, leading to cholinergic excess; atropine competes with Ach at muscarinic receptors

Front 19

treatment for a patient with QRS interval >100 msec?

Back 19

sodium bicarbonate

reverses QRS prolongation by increasing EC Na+ concentration

Front 20

signs/Sx of beta-blocker overdose

Back 20

bradycardia
hypotension
(bronchospasm)
(hypoglycemia)

may lead to cardiogenic shock