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23 Cards in this Set

  • Front
  • Back
what should you do when a pt ingests lye drain cleaner (sodium hydroxid)?
do not attempt to neutralize, vomit or charcol

get upper GI studies and/or endoscopy
what do you give for an imipramine (TCA) overdose and what are the effects of the antidote?
sodium bicarbonate

alleviates the depressant action on the sodium channels thus preventing QRS prolongation
what are the characteristics of a diphenhydramine overdose?
anti-histamine effects:
- drowsiness/confusion

anti-cholinergic effects:
- dry mouth
- dialated pupils/blurry vision
- reduced bowel sounds
- urinary retention
what is used to treat a diphenhydramine overdose?
physostimine
(cholinesterase inhibitor)
what type of overdose can cause hypothermia?
typical antipsychotics (fluphenazine) disrupts the bodies thermoregulation (shivering) mechanism
what does phencycladine overdose cause?

txt?
classically vertical nystagmus
- psychotic/violent behavior
- HTN
- hyperthermia

(txt: acidify urine, haloperidol for psychotic behavior)
what are the characteristics of ethylene glycol poisoning?
hypocalcemia, calcium oxalate deposition in the kidneys and subsequent acute renal failure
what does b-blocker overdose cause?
AV block (cardiogenic shock)
hypotension
wheezing
what is first/second-line txt for b-blocker overdose?
1st: atropine + IV fluids

2nd: glucogon
what are signs of opiod withdrawal on exam?
mydriasis
piloerection
incr bowel sounds
what do you treat iron overdose with?
deferoxamine
(binds ferric iron for urinary excretion)
what is the Rumack-Matthew nomogram?
it determines the likelyhood of liver toxicity in an acetaminophen overdose

4 hour after ingestion, acetaminophen levels should be checked and n-acetylcysteine is given based on these levels (8 hour window of txt)
what are the txts (3) of ethylene glycol poisoning?
fomipizole/ethenol (ADH dehydrogenase inhibition)
sodium bicarbonate (alleviate acidosis)
hemodialysis (if organ damage)
what are the characteristics of methanol poisoning?
looks like EtOH at first
N/V/HA/epigastric pain
optic disc hyperemia
anion gap metabolic acidosis
coma/vision loss (worst case)
what are the characteristics of a TCA overdose?

txt?
CNS depression
hypotension
anticholinergic (mydriasis, ilieus)
QRS prolongation

(txt: sodium bicarbonate)
what are the characteristics of neuroleptic malignant syndrome (NMS)?
typical antipsychotics (dopaminergic antagonist)
confusion
fever
muscle rigidity
diaphoresis
elevated serum CK
leukocytosis
what is the treatment protocol (3) for a patient with neuroleptic malignant syndrome (NMS)?
dantrolene (muscle relaxant)
bromocriptine (dopamine agonist)
amantidine (antiviral w/ dopaminergic properties)
how do you treat torsades de points?
magnesium sulfate
how do you differentiate between EtOH and benzodiazepine poisoning?
EtOH will have nystagmus
how do you differentiate between an opiod and a benzodiazepine poisoning?
opiod will have respiratory depression and miosis (except in coingestions)
what's the definition of an iron overdose?
serum iron concentrations >350 mcg/dL
what are the characteristics of an opiod overdose?
miosis
decr mental status
hypotension
bradycardia
decr bowel sounds
decr respiratory rate (best prognostic indicator)
what happens in organophosphate poisoning?

txt?
acetylcholinesterase inhibitied -> cholinergic effects:
bradycardia
miosis
muscle fasciculations

txt: atropine