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13 Cards in this Set
- Front
- Back
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Postinfectious glomerulonephritis |
Recent B hemolytic strep infx edema, tea colored urine low serum C3, increased ASO titer "lumpy bumpy" immunofluorescence |
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IgA Nephropathy (Berger's Disease) |
Typically after URI or GI infx gross hematuria or persistent microscopic hematuria Normal C3 Tx: glucocorticoids, AceI with proteinuria |
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Wegener's Granulomatosis |
Granulomatous inflammation + necrotizing vasculitis hemoptysis, hematuria c-ANCA present, segmental necrotizing glomerulonephritis on biopsy Tx: high dose corticosteriods and cytotoxins |
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Goodpasture Syndrome |
Rapidly progressing glomerulonephritis + pulm hemorrhage males in mid 20's Hemoptysis, no upper resp tract involvement Linear anti-GBM deposits on IF hemosiderin-filled macrophages in sputum tx: plex, pulsed steroids |
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Alport's Syndrome |
Hereditary glomerulonephritis boys 5-20, a/w sensorineural deafness and eye disorders GBM splitting on EM |
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Minimal Change Disease |
Children, nsaids, lymphoma light microscopy wnl EM shows fusion of epithelial foot processes tx: steroids |
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FSGS |
Idiopathic, IVDA, HIV, Blacks, htn Microscopic hematuria, sclerosis in capillary tufts |
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Membranous nephropathy |
Most common in caucasians, solid tumors, HBV, syphillis, malaria, gold, renal vein thrombosis "Spike and Dome" 2/2 IgG and C3 at BM |
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Diabetic nephropathy |
1. diffuse hyalinization 2. nodular glomerulosclerosis (KW lesions) Thickened GBM, increased mesangial matrix |
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Lupus Nephritis |
Nephrotic and nephritic, mesangial proliferation, sub endo/epithelial immune complex deposition |
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Membranoproliferative Nephropathy |
HCV, cryoglobulinemia, SLE, SBE 8-30 yrs if idiopathic Tram track double layered basement membrane Low C3 in serum |
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Nephrotic Syndrome |
Proteinuria, generalized edema, hypoalbuminemia, hyperlipidemia |
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Nephritic Syndrome |
PHAROH Proteinuria Hematuria Azotemia RBC casts Oliguria Hypertension |
