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32 Cards in this Set
- Front
- Back
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5 types adult brain tumors
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gliobastoma multiforme
meningioma schwannoma oligodendroglioma pituitary adenoma |
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gliobastoma multiforme=
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grade IV astrocytoma
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MC primary brain tumor
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gliobastoma
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malignant; life expectancy < 1 yr
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gliobastoma
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found in cerebral hemispheres
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gliobastoma
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can cross corpus callosum
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gliobastoma
"butterfly glioma" |
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gliobastoma stain
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stain astrocytes for GFAP
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"pseudopalisaiding" pleomorphic tumor cells - border central area of necrosis and hemorrhage
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gliobastoma
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2nd MC primary brain tumor
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meningioma
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most often occurs in convexities of hemispheres (near surfaces of brain) and parasagittal region
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meningioma
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arises from arachnoid cells
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meningioma
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are extra-axial (external to brain parenchyma)
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meningioma
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may have a dural attachment ("tail"
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meningioma
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typically benign + resectable
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meningioma
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often no sx; may present w/ seizures or focal signs
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meningioma
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spindle cells concentrically arranged in whorled pattern
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meningioma
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psammoma bodies
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(laminated calcifications)
meningioma |
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3rd MC primary brain tumor
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schwannoma
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schwann cell origin
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schwannoma
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often localized to CN VIII
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schwannoma (acoustic neuroma)
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resectable or treated with stereotactic radiosurgery
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schwannoma
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usually found at cerebellar pontine angle
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schwannoma
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S-100 (+)
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schwannoma
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bilateral acoustic neuromas found in
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NF 2
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relatively rare, slow growing
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oligodendroglioma
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most often in frontal lobes
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oligodendroglioma
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chicken-wire capillary pattern
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oligodendroglioma
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prominent delicate vasculature
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oligodendroglioma
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"fried egg" cells
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oligodendroglioma
round nuclei with clear cyto / perinuclear halo |
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often has calcifications
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oligodendroglioma
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MC pituitary adenoma
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prolactinoma
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sequelae of pituitary adenoma
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bitemporal hemianopia (2/2 pressure on optic chiasm)
hyper- or hypo-pituitarism |
