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31 Cards in this Set

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Autosomal Dominant Diseases
382. Adult Poly Cystic Kidney Disease
383. Familial Hypercholestrolemia Disease
384. Hereditary Hemorrhagic Telengectasia (Osler-Weber-Rendu)
385. Hereditary Spherocytosis
386. Huntington’s Disease (chromosome 4p)
387. Marfan’s Syndrome
388. Neurofibromatosis (von Recklinghausen’s)
389. Tuberous Sclerosis
390. Von Hippel Lindau Disease
Autosomal Recessive
Diseases
391. Tay-Sachs
392. Gaucher’s
393. Niemann-Pick
394. Hurler’s
395. Von Gierke’s
396. Pompe’s
397. Cori’s
398. McArdle’s
399. Galactosemia
400. PKU
401. Alcaptonuria
--- Cystic fibrosis
X Linked Recessive Diseases
402. Hunter’s Syndrome
403. Fabry’s Disease
404. Classic Hemophilia A
405. Lisch-Nyhan Syndrome
406. G6Phosphatase deficiency
407. Duchenne’s Muscular Dystrophy
X Linked Recessive Diseases
402. Hunter’s Syndrome (L-Iduronosulfate Sulfatase deficincy, inc Heparan/Dermatan Sulfate)
403. Fabry’s Disease (ƒ¿ Galactosidase A deficiency, inc Ceremide Trihexoside)
404. Classic Hemophilia A (Factor VIII deficiency, F8 Gene on X chromosome is bad, inc Ceremide Trihexoside)
405. Lisch-Nyhan Syndrome (HGPRT deficiency, inc Uric acid)
406. G6Phosphatase deficiency (G6PDH deficiency, inc Ceremide trihexoside)
407. Duchenne’s Muscular Dystrophy (Dystrophin deficinecy, inc Ceremide Trihexoside)
Lung Development
Glandular: 5-17 fetal weeks
Canalicular 13-25 fetal weeks
Terminal Sac 24 weeks to birth
Alveolar period birth-8yoa
Irreversible Glycolysis
Enzymes
Hexokinase
PhosphoFructo Kinase = Rate Limiting Step
Pyruvate Kinase
Pyruvate Dehydrogenase
Irreversible Gluconeogenesis
Enzymes
PyruvateCarboxy Kinase
PEPCarboxyKinase
Fructose 1,6 BiPhosphatase
Glucose 6 Phosphatase
**muscle dose not take part in Gluconeogenesis, only takes place in the liver, kidney & GI epithelium
Pellagra
Diarrhea, Dermatitis, Dementia
Niacin Deficiency (Vit B3 deficiency)
Hartnup’s Disease
Malignant Carcinoid Syndrome
INH use
Lactose formers
1. “CEEK”
2. Citrobacter
3. Enterobacter
4. E.Coli (K1 capsule most important)
5. Klebsiella
Non lactose formers
6. “SHYPS”
7. Shigella: motile H2S+
8. Yersinia enterolytica (AKA Pestis): motile H2S+
9. Proteus: nonmotile, no H2S
10. Salmonella: nonmotile, no H2S
May lack color
11. “These rascals may microscopically lack color”:
12. Treponema
13. Ricksetta
14. Mycobacterium
15. Mycoplasma
16. Legionella
17. Chlamydia
inc cAMP
18. "CAPE"
19. Cholera
20. Anthracis (Poly D glutamate capsule)
21. Pertusis (via Gi)
22. E.coli (LT enterotoxin)
Have Capsules [ie… are Quellung Reaction (+)]
23. “Some killers have pretty nice capsules”
24. Strep. Pneumoniae
25. Klebsiella
26. HiB
27. Pseudamona Aeroginosa
28. Neisseria meningitis
29. Cryptococcus neoformans (only encapsulated fungal pathogen)
Dimorphic Fungi
30. "Can Also Have Both Shapes"
31. Cocciodes
32. Aspergillus
33. Histolpasma
34. Blastomyces
35. Sprothrix schenkii
Have â Prophage
36. "OBED"
37. O = Salmonella
38. B = Botulinum
39. E = Erythrogenic strep
40. D = Diptheria
Pigment Producing Bacteria
56. Serratia – red (can cause pseudohemoptysis)
57. Pseudomonas A – piocyanin blue/green
58. Staph Aureus – yellow – Protein A
59. Mycobacteria – photo/scoto chromogenic – caritinoid – yellow/orange
60. Corneybacterium D – black/gray – pseudomembrane plaque in throat
61. Bacteroides (Porphyromonas) melaninogenicus – black (heme)
62. E. coli – irredescent green sheen
Bacterial Morphology
63. Pneumococci – lancet shaped diplococci
64. Neisseria – kidney bean shaped diplococci
65. Camphylobacter - gulls - wings/comas
66. Vibrio Cholera - coma shaped
67. Corneybacterium D - club shaped (nonmotile, G+Rod)
68. Yersinia - safety pin seen in Wayson's stain
Inclusion Bodies
69. Rabies – Negri bodies – intracytoplasmic
70. Pox virus – Guarnieri – intracytoplasmic & acidophilic
71. CMV – Owl’s eyes – intracytoplasmic & intranuclear
72. HSV – Cowdry bodies – intranuclear
Urease (+)
82. All Proteus – can cause Staghorn/Struvite calculi (NH4
- Mg2- stones): alkaline urine
83. Ureaplasma
84. Campylobacter pylori (Helicobacter)
85. Cryptococcus
86. Nocardia
Mycoplasma
94. No cell wall. Membrane has cholesterol. Smallest living bacteria.
95. P1 protein inhs ciliary action
96. Fried egg colonies
97. Atypical pneumonia – young adults
Need Cysyeine for growth
107. “Ella likes cysteine”:
108. Francisella
109. Brucella
110. Legionella
111. Pasturella
Chlamydiae Developmental Cycle
181. Elementary Body: infeccious particle that Enters the cell
182. Reticulate Body: made from elementary body. Replicates, differentiates and releases
elementary bodies to infect other cells
183. W/ infection you will see Glycogen containing inclusions
184. Cell wall lacks muramic acid
Orthomyxovirus
212. –ssRNA, enveloped virus.
213. Spike Glycoproteins (peplomeres): HA = Hemagluttinin & NA = Neuraminidase. These
peplomeres are what give the virus antigenis variation
214. Influenza A & B
Paramyxovirus
215. –RNA, enveloped. Most common cause of respiratory infections in kids
216. Mumps
217. Croup(Parainfluenza virus)
218. Rubeola(Measles virus)
219. RSV
Togavirus
220. +ssRNA, enveloped
221. 3 Day Measles: German Measles: Rubella/ Rubivirus
222. Encephalitis viruses: Alphaviruses: Eastern (more severe) and Western Equine
Encephalitis
Flaviviris
223. Dengue Fever - icterus & hemorrhage w/ blac vomit
224. Yellow fever
225. St. Louis Encephalitis – no hepatitis or hemorrhage
Bunyavirus
226. –ssRNA, enveloped
227. California Encephalitis – severe bifrontal headaches
228. Hantavirus – hemorrhagic fever w/ acute resp. distress syndrome
IgA Protease Activity
229. H. Influenzae (needs factors V & X for growth)
230. Strep. Pneumoniae
231. N. meningitidis
232. N. gonnorhoae
233. W/ this activity these bugs are able to colonize the oral mucosa.
Diphtheria: ABCDEFG
234. Adenopathy
235. â Prophage encodes the exotoxin
236. Corneybacteria is Club shaped
237. Diphtheria
238. Elongation Factor II
239. Granules (metachromatic)
"Hot T-Bone stEAk": ILs
IL1 = inc Temp: HOT
IL2 = stimulate T cells
IL3 = stimulate Bone Marrow stem cells's growth & differentiation (GM CSF)
IL4 = stimulate IgE (& IgG)
IL5 = stimulate IgA (& eosinophils)
Plasmodium Life Cycle
Sporozoites: from blood to liver
Primary tissue schizont
Trophozoites: in RBC
Erythrocytic schizont
Merozoite: ruptured RBC
Gametozyte
Zygote: inside the mosquito