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23 Cards in this Set
- Front
- Back
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What part of the lymph node enlarges when you have a viral infection?
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The paracortex (houses the TCells as well as the high endothelial venules that allow T and B cells to enter from circulation)
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What are the different parts of the lymph node medulla?
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Cords = Plasma cells (& lymphocytes) packed closely
Sinuses = Macrophages (& reticular cells = fibroblasts/collagen III) filtering |
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What are the parts of the lymph node follicle?
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Primary follicle = dormant/dense
Secondary follicle = active germinal centers (pale in the center) |
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What is the lymph drainage for the upper limb and lateral breast?
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Axillary lymph node
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What is the lymph drainage for the stomach?
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Celiac LN
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What is the lymph drainage for the duodenum?
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Superior Mesenteric LN
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What is the lymph drainage for the jejunum?
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Superior Mesenteric LN
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What is the lymph drainage for the sigmoid colon?
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Colic → Inferior mesenteric LN
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What is the lymph drainage for the Rectum (above the pectinate line)?
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Internal iliac
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What is the lymph drainage for the anal canal (below the pectinate line)?
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Superficial inguinal
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What is the lymph drainage for the testes?
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The superficial and deep plexuses → Para-aortic LN
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What is the lymph drainage for the scrotum?
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Superficial inguinal
All "superficial" structures drain to superficial inguinal |
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What is the lymph drainage for the superficial thigh?
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Superficial inguinal
All "superficial" structures drain to superficial inguinal |
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What area is special in that it drains to the popliteal LN?
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The lateral side of the dorsum of the foot (over and out)
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What are the major lymph ducts and what drains into them?
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1) Right Lymphatic Duct (drains right half of head and right arm)
2) Thoracic duct = everything else! |
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Where does the thoracic duct drain?
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At the junction of:
- L Subclavian vein - L Internal jugular dUct --> sUb jUg |
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What kind of fenestrations are found in the red pulp of spleen?
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"Barrel hoop" basement membranes
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Where are TCells found in the spleen? BCells?
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Both are in the "White Pulp" surrounded by red pulp and w/ a central arteriole.
1) TCells: - PALS = peri-arterial lymphatic sheath surrounding the central arteriole - Throughout the white pulp 2) BCells = Follicles (germinal centers) |
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What vaccines should someone get if they don't have a spleen?
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ABC's of Spleen Vaccines
1) PneumovAx (S. pneumoniae) 2) Flu shot (H. Influenza B) 3) MeningoCoCCal (N. meningitides) |
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What blood changes are you going to see in someone that's had a splenectomy?
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Weird RBC's and High Platelets:
1) Howell-Jolly bodies (w/ nuclear remnants) 2) Target cells 3) Thrombocytosis |
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What cells are in the cortex of the thymus? The medulla?
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Cortex = Immature T Cells (dense)
Medulla = - Mature TCells (pale) - Epithelial reticular cells (present their genome to incoming TCells; if recognize, are destroyed) - Hassall's corpuscles (made by endothelial reticular cells) |
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What kind of selection occurs in the thymus and where?
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@ the Cortico-Medullary junction:
- Positive - MHC restriction - Negative - Nonreactive to self |
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From what branchial pouch does the thymus develop?
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Third (THYrd) branchial pouch
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