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21 Cards in this Set
- Front
- Back
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Bethanechol
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direct cholinergic agonist
activates bowl and bladder SM. resistance to AchE. used for post-operative and neurogenic ileus and urinary retention |
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Carbachol
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direct cholinergic agonist
used for eye stuff (glaucoma, pupillary constriction, decrease IOP) |
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Pilocarpine
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direct cholinergic agonist
potent stimulation of sweat, tears, and saliva |
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Methacholine
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challenge test for diagnosis of asthma
stimulates muscarinic receptors in airway when inhaled |
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Neostigmine
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anticholinesterase (indirect agonist)
Postop and neurogenic ileus and urinary retention. myasthenia gravis, reversal of NM junction block (postop) |
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Pyridostigmine
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anticholinesterase (indirect agonist)
Myasthenia gravis (long acting), does not penetrade CNS |
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Edrophonium
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anticholinesterase (indirect agonist)
Dx of myasthenia gravis (extremely short acting) |
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Physostigmine
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anticholinesterase (indirect agonist)
Used for glaucoma (crosses BBB unlike neostigmine) and atropine OD |
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Echothiophate
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anticholinesterase (indirect agonist)
Used in glaucoma |
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Benztropine
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muscarinic antagonist
Used in Parkinson's dz |
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Scopolamine
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muscarinic antagonist
used for motion sickness |
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Ipratropium
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muscarinic antagonist
active in the respiratory system used in asthma, COPD |
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Oxybutynin and
glycopyrolate |
muscarinic antagonist
active in the GU system reduces urgency in mild cystitis and reduce bladder spasms |
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Methscopolamine, pirenzapine, propantheline
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muscarinic antagonist
active in GI tract peptic ulcer tx |
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atropine toxicity
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muscarinic antagonist
toxicity: Hot as a hare Dry as a bone Red as a beet Blind as a bat Mad as a hatter |
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Ritodrine
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Beta2 agonist
reduces premature uterine contractions |
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phenoxybenzamine
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Irreversible alpha blocker
used in pheochromocytoma preop because high levels of catecholamines will not overcome the block |
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phentolamine
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reversible alpha blocker
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toxicity of alpha blockers
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orthostatic hypotension, reflex tachycardia
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alpha1 selective blockers
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-zosin
eg- prazosin, terazosin, doxazosin used to treat HTN, urinary retention in BPH toxicity: 1st dose orthostatic hypotension, dizziness, headache |
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Mirtazapine
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alpha2 selective blocker
depression tx toxicity: sedation, increased serum cholesterol, increased appetite |
