Usmle Cardiovascular

Front 1

–Assoc. w/polymyalgia rheumatica
–Increased ESR


–Unilateral headache
–Jaw claudication

Back 1

Temporal (Giant cell) arteritis

Tx: high dose steroids (for up to 1 year)

Front 2

–Granulomatous thickening of the aortic arch
–Increased ESR


–Fever, night sweats, arthritis, myalgias, skin nodules
–Young Asian females (<40 y.o.)

Back 2

Takayasu arteritis

Front 3

–Fever, headache, malaise
–Abdominal pain, wt. loss (duh...), melana

Lab= – p-ANCA

Often Hep B+

Back 3

Polyarteritis Nodosa (PAN)

Tx: Corticosteroids & cyclophosphamide

Front 4

–Fever, lymphadenitis, conjunctivitis

+ Strawberry tongue
+Desquamation of hands/feet, erythemia too

–Asian kids < 4 y.o.

Back 4

Kawasaki Disease

Front 5

–Intermittent claudication
–Raynaud Phenomenon
–Males <40 y.o.
–Heavy SMOKER

Back 5

Buerger Disease (aka Thromboangiitis obliterans)

Front 6

Two +p-ANCA diseases:

1.)_____________
2.)_____________

Back 6

+p-ANCA diseases

1.) Churg-Strauss disease
2.) Microscopic Polyangiitis

Front 7

Name two LARGE vessel vasculitides:

1.) _______________
2.) _______________

Back 7

LARGE Vessel Vasculitides:

1.) Giant Cell Arteritis (Temporal Arteritis)
2.) Takayasu Arteritis

Front 8

Name two medium vessel vasculitides:

1.) ________________
2.) ________________

Back 8

Medium Vessel Vasculitides:

1.) Polyarteritis Nodosa
2.) Kawasaki disease

Front 9

1.) Focal Necrotizing Vasculitis
2.) Necrotizing Granulomas in upper airway AND the lung
3.) Necrotizing GLN


Dx? Tx?

Back 9

Wegener Granulomatosis

Tx: Cyclophosphamide, corticosteroids

Front 10

–Palpable purpura, Sinusitis, Wrist/Foot drop
–Asthma


+/– heart, kidney, GI involvement

Back 10

Churg Strauss

Front 11

1.) Palpable purpura
2.) Arthralgia
3.) GI Pain; Melana


–IgA immune complexes
–Post-URI in children

Back 11

Henoch-Schonlein purpura

Front 12

–A large raised red lesion on face
–Port-wine stain
–Seizures


–Leptomeningeal Angiomatosis (ipsilateral)

Back 12

Sturge-Weber disease

Front 13

_______________ is a skin lesion found in AIDS patients that is mistaken for Kaposi sarcoma

Back 13

Bacilary angiomatosis

Front 14

Highly lethal malignancy assoicated with vinyl chloride & arsenic exposure: ______________

Back 14

Angiosarcoma


Where is this sarcoma found?














LIVER (not in BV's)

Front 15

Scary sequelae of Takayasu?

Back 15

IRREVERSIBLE Blindness!

Front 16

What other name describes Takayasu disease?

Back 16

"Pulseless disease"

(due to the weak upper extremity pulses)

Front 17

Which specific vessels does PAN affect/avoid?

Back 17

Affects- Renal & visceral arteries
Avoids- Pulmonary arterties

Front 18

Kawasaki Disease Feared Complication?

Back 18

Coronary Aneurysm!!!

Tx: IV Ig
Aspirin (high doses!)






Screw Reye Syndrome, these kids will have MI's! Give 'em ASA

Front 19

Buerger Disease (aka Thromboangiitis obliterans) Feared complication???

Back 19

+/– gangrene
+/– autoamputation


Tx = Smoking cessation!

Front 20

Two +p-ANCA diseases:
1.) Churg-Strauss disease
2.) Microscopic Polyangiitis

"How the hell do you tell them apart?"

Back 20

Churg Strauss:
–Granulomatous
–Eosiniphilia



Microscipic polyangiitis:
NOT A DAMN GRANULOMA IN SIGHT!!!

Front 21

What two renal symptoms Wegener disease present with?

Back 21

1.) Red Cell Casts
2.) Hematuria

Front 22

Where is the MC place to see the Henoch_Schonlein palpable purpura?

Back 22

Purpura on buttocks & legs

Front 23

Feared Complication of Sturge-Weber disease????

Back 23

Intracerebral AVM

(& early onset glaucoma)

Front 24

Bacilary angiomatosis


Benign or Malignant?

Back 24

Flat-ass Benign!