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13 Cards in this Set
- Front
- Back
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Chronic granulomatous disease is a deficiency of
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NADPH oxidase
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Hexokinase is found in
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all cells
ubiquitous |
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Glucokinas is found in
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liver
pancreatic beta cells |
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Hexokinase v. Glucokinas
which is induced by insulin? |
Hexokinase is inhibited by insulin
Glucokinase is stimulated by insulin |
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What reaction does
Hexokinase/Glucokinase perform and why? |
Glucose --> Glucose6-P
to trap it in liver cells |
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G6PD deficiency causes
and name the histo sign |
hemolytic anemia
Heinz bodies |
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Fructose metabolism:
aldolase B deficiency causes accumulation of |
fructose 1-P
decreases available phosphate, resulting in inhibition of glycogenolysis |
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Fructose metabolism:
aldolase B deficiency causes what sx |
hypoglycemia
jaundice cirrhosis vomiting hepatomegaly |
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Fructose metabolism:
fructokinase deficiency causes what sx |
no sx, except fructose in the urine and blood
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Galactose metabolism
Absence of 1-P-uridyltransferase causes accumulation of |
accumulation of toxic substance (inc galactitol)
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Galactose metabolism
Absence of 1-P-uridyltransferase causes what sx |
cataracts
mental retardation hepatosplenomegaly |
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What aa are required during periods of growth
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Arg
His |
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Name the acidic aa
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Asp
Glu |
