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15 Cards in this Set
- Front
- Back
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What originates in the neuroectoderm?
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CNS neurons, ependymal cells (make CSF), oligodendroglia, astrocytes
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What originates from the neural crest?
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Schwann cells, PNS neurons
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What originates in the mesoderm?
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Microglia and Macrophages (remember M)
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Glial (supporting cells) can regenerate. T/F
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True, unlike neurons
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What do astrocytes do?
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Form structural support for CNS, contain large bundles of filaments called GFAP, remove glutamate & K+ from EC space, BBB maintenance, fill up EC space in rxn to to CNS injury
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What do microglia do?
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CNS phagocytes
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Microglia are not seen in Nissl stains T/F
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True
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HIV infects which CNS cell to form multinucleated giant cells?
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microglia
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What do oligodendrocytes do?
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form myelin for axons in CNS
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What do oligodendrocytes look like under the microscope?
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Fried eggs - H & E staining
Small nuclei, dark chromatin, little cytoplasm - Nissl stains |
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What do Schwann cells do?
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forms myelin in the PNS, promote axonal regeneration
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Schwann cells form myelin for multiple axons. T/F
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False, only 1. Oligodendrocytes can myelinate up to 30 each.
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What is a node of Ranvier?
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region between adjacent myelinated segments of axons
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What is Wallerian (anterograde) degeneration?
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axon injury --> neuron degneration distally, axonal rxn (cellular swelling, Nissl substance dispersal) proximally
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Nissl substance is found in the axon. T/F
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False, only cell body and dendrites
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