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3 Cards in this Set
- Front
- Back
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When should acid suppression be commenced?
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If;
i) endoscopy has demonstrated a non-variceal cause of bleeding in the oesophagus, stomach or duodenum ii) clinical presentation suggest an UGIB |
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What is the benefit of PPI in pts with UGIB?
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Prevent re-bleeding episodes and significantly reduce the need for surgery when used for the initial phase in patients with an acute UGIB
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What are the recommended regimens?
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i) pantoprazole 40mg PO 8hrly for 24 hours followed by 40mg bd
ii) pantoprazole 80mg iv, followed by 40mg IV bolus 8hrly for the first 24 hours. Thereafter, the dose should be reduced to 40mg bd PPI therapy should be given ORALLY unless there is evidence absorption of PO administered PPI might be impaired - haemodynamically unstable of haematemesis Oral PPI should be used as soon as possible (clinically stabilised, haematemesis stopped, oral intake reinitiated - clear fluids). |
