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13 Cards in this Set

  • Front
  • Back

The urea cycle involves the transportation of which enzyme via the mitochondria into urine ?

AMMONIA

Urea cycle begins where ?

The urea cycle begins within the mitochondrial matrix of the cell.

In step 1 the enzyme that catalyses this step of the urea cycle ?

Carbomoyl phosphate synthatase

CO2 is formed via the Biocarbonate but requires ATP to produce what ?

Carboxyphosphate

The carbomoyl phosphate releases ammonia as substrate and requires second ATP for Carbonic acid to produce ?

Carbomoyl phosphate which is the first amino group.

But the carbomoyl phosphate synthatase can only be activated via what ?

N - acetyl glutamate

The Carbomy phosphate then kicked off to make Ornithine catalysed by what?

Ornitihine transcarbamylase that makes Citrulline.

The Citrulline moves into what part of the cell ?

Cytoplasm of the cell.

The second amino group made is ?

Asparate needed to transfer H3N from asparate

Asparate to form Argininosuccinate is made possible by which enzyme?

Argininosuccinate synthatase whcih uses both ATP - AMP and PPI pyrophosphate.

Arginosuccinate then reacts with Arginosuccinase to release carbon skeleton and make

Arginine and Fumerate has a link with gluconeogenesis to form glucose.

The Arginine formed from previous step of the enzyme reacts via Arginase a water molecule to attack + hydrolise and forms what?

Ornithine that enters the urea.

Name the 2 amino groups essential for the urea cycle ?

Carbomyol phosphate


Asparate