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7 Cards in this Set
- Front
- Back
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glutamate--> glutamine |
-catalyzed by glutamine synthetatse -uses atp -amino group is transferred to glutamate |
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urea into liver |
-glutamine crosses through tissue membrane into liver -glutaminase reverts it back to glutamate -consumes H2O and releases NH4 -in muscle Glu --> pyruvate-> alanine which travels to liver then reverse to Glu |
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Nitrogen balance |
-avg N= (80g/day + 70g/day absorbed)- (10 lost to fecal +70 lost urine) -(+) balance: growing, fed, muscle building, pregnant, some trauma cases - (-) fasting, trauma |
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Gluc ketog |
Ille, Phe , thre, trp |
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ALT (alanine transferase) |
-in liver -transfers NH3 from Ala to Glu - produces pyruvate -ALT is liver dysfunction marker - B6 is cofactor |
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every amino acid has specific amino transferase except |
Threonine and Lysine |
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hyperammonuria treatment |
- less protein intake -more alpha ketoacids |
