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12 Cards in this Set

  • Front
  • Back

Antacids

NaHCO3


Mg


Al

Alginates

Form raft

H2 receptors antagonists

CIMETIDINE


RANITIDINE


FAMOTIDINE


ranitidine is selective and has few drug metabolising interactions

PPIs

Omeprazole


Pantoprazole


Lansoprazole


Omep and lansopa are OTC in low dose

Prokinetic

Domperidone-sphincters


Metoclopramide-motility and emptying

Triple therapy

2 from:


Metronidazole-no alcohol


Amoxicillin


Clarithromycin


And a PPI/H2 antagonist


(For 1 week and then PPI alone)

H. Pylori eradication

Bismuth chelate kills, coats ulcer, absorbs pepsin, increases inhibitory prostaglandins and increases hco3- secretion


Non-H. Pylori dyspepsia Step 1

Antacid alone or with alginate

Non-H. Pylori dyspepsia Step 2

H2 antagonist

Non-H. Pylori dyspepsia Step 3

PPI

Selective cox-2 inhibitor

Celecoxib

Minimising GI damage

PPI prophylaxis


Give with misoprostol


(H2 antagonists ineffective)