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33 Cards in this Set

  • Front
  • Back
What lymphoma is common in young adults?
Hodgkin's Lymphoma
What are the B symptoms?
Fever over 100.4
Night sweats
Weight loss over 10% body weight
What size lymph node is considered pathologically enlarged?
Over 1 cm
What are the two main types of Hodgkin lymphoma?
Nodular lymphocyte predominant
What are the diagnostic findings of Hodgkin lymphoma?
Reed-Sternberg cell
Positive for CD30, CD15
What are the morphologic subtypes of classic Hodgkin's?
Nodular sclerosis
Mixed cellularity
Lymphocyte rich
Lymphocyte depleted
You can use an aspirate to diagnose lymphoma, true or false?
What tests are used to diagnose lymphoma?
Bilateral bone marrow biopsies
What is the chemo regimen for Hodgkins?
Adriamycin, Bleomycin, Vinblastine, Dacarbazine
What is the 5 year freedom from progression rate in Hodgkins?
What is the most common low-grade non-Hodgkin lymphoma?
Follicular lymphoma (22%)
What is the median age for diagnosis of follicular lymphoma?
60-70 years of age
What are the findings on a blood smear of a patient with follicular lymphoma?
Small cleaved cells
What is found on flow cytometry in follicular lymphoma?
What do follicular lymphoma cells consist of?
Centrocytes - Small cleaved cells
Centroblasts - larger cells that divide more
A large number of centroblasts indicates what in follicular lymphoma?
More aggressive
The mantle zone, polarization of germinal center, and paracortex are lost in what lymphoma?
Follicular lymphoma
What translocation is found in 85% of patients with follicular lymphoma?
MALT lymphoma makes up what percentage of primary gastric lymphomas?
What infection is western MALT associated with?
Chronic H.pylori infection
Salivary gland MALT lymphoma can cause what?
Sjogren's syndrome
A MALT lymphoma in the GI tract can cause what?
Crohn's disease
A MALT lymphoma of the thyroid can cause what?
Hashimoto's thyroiditis
What is the treatment for MALT lymphoma
Treat H.pylori
Absence of t(11;18) is a good prognostic factor in what cancer?
MALT lymphoma
What is the percentage of remission in MALT lymphomas when H.pylori is treated?
What is the fastest growing lymphoma?
Burkitt's lymphoma
What does African Burkitt's lymphoma affect?
jaw, facial bone
What does American Burkitt's lymphoma affect?
lymph nodes in abdomen, GI tract
What is the pattern finding in the bone marrow of a Burkitt's lymphoma patient?
Starry sky pattern
Many patients will present in renal failure in what lymphoma?
Burkitt's lymphoma
What test assesses how much cell turnover exists, and is often elevated in cancer patients?
What are the treatments for Burkitt's lymphoma?
Complicated chemo