Unit 7 - 2 Taste/smell

Front 1

Loss of smell is a first sign of what kinds of disease

Back 1

Among the more important developments in neurology has been the discovery that decreased smell function is perhaps the first sign of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD), signifying their "presymptomatic" phase.

Front 2

What tastes use GPCR

Back 2

T1R1, T1R2: Sweet and umami; umami = flavors of meat, cheese an dbroth due to glutamate and related compounds

T2R: Bitter

Front 3

What tastes use transient receptor potential proteins (TRP?)

Back 3

PKD2L1: Sour

Front 4

What tastes use sodium channels?

Back 4

Salty

Front 5

VII

Back 5

anterior tongue

Front 6

IX

Back 6

posterior tongue

Front 7

X

Back 7

epiglottis larynx proximal esophagus sensation

Front 8

V

Back 8

somatosensory from tongue (spicy, temp)

Front 9

presbyosmia

Back 9

age associated loss of smell

Front 10

physiologic basis for head trauma related olfactory loss

Back 10

The physiologic basis for most head trauma–related losses is the shearing and subsequent scarring of the olfactory fila as they pass from the nasal cavity into the brain cavity

Front 11

some physiologic disorders that can affect taste

Back 11

(1) the release of foul-tasting materials from the oral cavity from oral medical conditions and appliances (e.g. gingivitis, purulent sialadenitis), (2) transport problems of tastants to the taste buds (e.g., drying of the orolingual mucosa, infections, inflammatory conditions), (3) damage to the taste buds themselves (e.g., local trauma, invasive carcinomas), (4) damage to the neural pathways innervating the taste buds (e.g., middle ear infections), (5) damage to central structures (e.g., multiple sclerosis, tumor, epilepsy, stroke), and(6) systemic disturbances of metabolism (e.g., diabetes, thyroid disease, medications).

Front 12

bells palsy

Back 12

affects VII which affects somatosensation from the tongue

Front 13

most likely mechanism of isolated CN IX damage

Back 13

tonsillectomy, bronchoscopy, laryngoscopy, and radiation therapy can result in selective injury

Front 14

sudden chemosensory loss

Back 14

head trauma, ischemia, infectoin or psychiatric condition

Front 15

gradual chemosensory loss

Back 15

progressive obstructive lesion

Front 16

intermittent chemosensory loss

Back 16

inflammatory process