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11 Cards in this Set
- Front
- Back
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Takayasu Arteritis
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Pulseless disease
Asia; affects young and middle aged women Narrowing of the major arterial branches; loss of pulse in the upper extremities bc affects aortic arch and major branches |
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Giant cell Arteritis
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temporal arteritis; primarily affects elderly females; associated with HLA-DR4; cranial arteries
Throbbing headache, tender firm temporal arteries, facial pain Elevated ESR Segmental granulomatous vasculitis; fragmentation of the internal elastic lamina biopsy tx w steroids |
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Polyarteritis Nodosa
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Immune complex mediated transmural vasculitis with fibrinoid necrosis
Hep B association systemic vasculitis EXCEPT LUNGS |
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Kawasaki Disease
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Asian children; Japan; segmental necrotizing vasculitis which affects coronary aneurysms (Strawberry tongue
"Mucocutaneous lymph node syndrome") |
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Churg-Strauss Syndrome
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Allergic granulomatosis and angitis
Variant of PAN Associated w asthma; systemic necrotizing vascluitis with granulomas and EOSINOPHILIA; classically involves the nose, sinuses, lungs and kidneys p-ANCA Often peripheral neuropathy (wrist/foot drop) |
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Wegener's Granulomatosis
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Triad:
1. Necrotizing vascultis 2. Necrotizing Glomerulonephritis 3. Necrotizing granulomas (lung + upper airways) c-ANCA is strong marker |
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Microscopic Polyangiitis
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Like Wegener's but lacks granulomas
p-ANCA affects small vessels |
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Sturge Weber Disease
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Vascular disorder that affects capillary sized blood vessels
Port wine stain on face |
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Buerger's Disease
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Thromboangiitis obliterans
Young males + heavy smoking; involves extremities Segmental thrombosis leads to vascular insufficiency Tx: smoking cessation |
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Raynaud's Disease
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Decreased blood flow to the skin due to arteriolar vasospasm in response to cold temperature or emotional stress; often in fingers and toes
Called Raynaud's phenomenon when secondary to a mixed connective tissue disease, SLE or CREST syndrome affects small vessels Cyanosis of fingers or toes precipitated by cold temperature and emotions w no underlying disease or pathology |
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Raynaud's Phenomenon
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Arterial insufficiency secondary to an underlying dz (SLE, buerger dz, atherosclerosis, scleroderma)
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