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30 Cards in this Set

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Briefly describe the role of prostaglandins in producing inflammation??
Sensitive pain receptors and increase pain associated with chemical mediators of inflammation and immunity.
What is the role of NSAIDs in decreasing prostaglandin production and activity?
Inhibits the synthesis of prostaglandins.
What does Aspirin prevent?
What does Aspirin cause?
What are adverse effects of Aspirin?
Pain, fever, osteoarthritis
Nausea and Vomiting
GI bleed and renal impairment
What does Ibuprophen prevent?
What does Ibuprofen cause?
What are some adverse effects?
Pain, fever, osteoarthritis
Nausea, vomiting, GI bleed
N/A
What does Celecoxib prevent?
What does it cause?
What are some adverse effects?
treats pain and osteoarthritis
causes nausea, vomiting and GI bleed
What does Tylenol prevent?
pain, fever and osteoarthritis
This is a normal response to tissue damage?
Inflammation
This is inflammation of a cavity in connective tissue that contains synovial fluid?
bursitis
This is the drug of choice for pain of fever in children?
Acetaminophen (Tylenol)
These are chemical mediators found in most body tissues?
prostaglandins
This is effective in low to moderate pain involving the skin, muscles, joints and connective tissue?
Aspirin
This is an essential structural component of joint connective tissue?
Glucosamine
This is a chronic, painful, inflammatory disorder that effects joints and has systemic effects?
Rheumatoid Arthritis
This is a fever producing agent?
Pyrogen
This syndrome is a disease seen in children under 15 that is associated with the use of aspirin?
Reye's Syndrome
All the following factors predispose a person for infection except: A. impaired blood supply
B. Hypertension
C. Suppression of Immune System
D. Advanced Age
B. Hypertension
Some antimicrobial drugs work by:
A. Enhanced Cell Metabolism and Growth
B. Promoting protein synthesis
C. Inhibiting cell wall synthesis
D. Stimulating bacterial reproduction
C. Inhibiting Cell Wall Production
Antimicrobial meds are usually administered using how many drugs for how many days?
1 drug for 7-10 days
Overuse of antibiotics is not recommended because it will result in?
antibiotic resistant material
True of false??
Beta-Lactam antibacterial drugs inhibit synthesis of bacterial cell walls by binding to proteins in bacterial cell membranes. This binding produces a defective cell wall that allows intracellular contents to leak out?
True
After the first administration of penicillin, a patient needs to be watched for how long, since this is when anaphalaxis is most likely to occur?
30 minutes
Your client weighs 88 lbs and is to receive Unipen 50 mg/kg/day in 4 doses. How many milligrams should be given per dose?
88/2.2=40*50=2000/4=500 mg per dose
True of False?
Probencid can be given concurrently with penicillins to prevent an anaphylactic reaction?
FALSE!!! because procencid acts to block renal excursions of penicillin
What are some risk factors for developing an infection, including with antibiotic resistant microorganism?
* type of bacteria
* type of infection
* using a lot of antibiotics
What do antibacterial drugs do?
prevent or treat infections caused by pathogens (disease producing organisms)
What are some ways nurses can promote rational use of antimicrobial drugs??
*not for viruses
*take meds as prescribed
*Dr. should do culture before taking giving any meds
What are 2 objective signs of anaphylactic shock?
hives and laryngeal edema
What is the rationale fro combining beta-lactamase inhibitors with penicillin?
inhibit cell walls by binding to proteins
What are some uses and effects of macrolide antibiotics?
*used to treat gonorrhea and syphillis in patients who can't tolerate penicillin or tetracycline
*minor staphylococcal infections of the skin
Why is the use of vancomycin restricted?
Severe adverse effects such as anaphylaxis, eosinophilia, neutropenia and hearing loss