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126 Cards in this Set

  • Front
  • Back
Parts of the Pancreas
1. Head
2. Uncinate Process
3. Body
4. Tail
The majority of the pancreas lies where?
Retroperitoneal Cavity, except for a small portion of the head that is surrounded by peritoneum.
Why is the pancreas considered to be technically challenging?
Due to it's location which is posterior to the stomach, duodenum, and proximal small bowel
What is the normal length of the pancreas?
about 15 cm
Range (12-18 cm)
The pancreatic head is bordered by the following.
1. Anterior to the IVC
2. Cauded to the Portal Vein
3. to the RT of the portal Splenic Confluence
4. Inferior to the caudate lobe of the liver
What is the thickest part of the pancreas and it's measurements?
The HEAD and it measures between 2.0 and 3.5 cm A/P
Describe the uncinate process.
It is the small curved tip at the end of the head of the pancreas.
The uncinate process is bordered by the following:
1. Anterior to the IVC
2. Posterior Medial to the SMV
The pancreatic neck is bordered by the following:
Anterior to the portal-splenic confluence
Where is the pancreatic neck located?
Between the head and the body and is often included as part of the body
What is the measurement of the pancreatic neck?
1.5-2.5 cm A/P
What section/division of the pancreas is the largest?
BODY

The head is the thickest and the body the largest portion.
What is the sonographic pancreatic landmark?
The Splenic Vein and it courses across the posteromedial surface of the pancreas to join the main portal vein
What is the measurement of the pancreatic body?
2.0 to 3.0 cm A/P
Can the tail of the pancreas be difficult to image?
Yes, due to it's location
The following are the borders of the pancreatic tail?
1. Begins to the left of the aorta and extends toward the Splenic Hilum

2. Anterior border is the Splenic Artery and Stomach

3. Posterior border is the Splenic Vein
What is the measurement of the pancreatic tail?
1.0 to 2.0 cm A/P
Describe the difference between children's pancreas' and adult pancreas'.
Children's is larger and less echogenic

***Child larger and darker****
What is most likely the cause of Jaundice in a child?
Biliary Atresia
What on ultrasound can mimic a pancreatic mass?
DUODENUM
How does the pancreas look as a person becomes old and why?
more echogenic due to fatty replacement of the gland's tissue
The pancreatic duct is also known as ...
Duct of Wirsung
The pancreatic duct extends...
the entire length of the gland (pancreas)
The pancreatic duct enters...
the duodenum with the CBD at the ampulla of Vater
What is the function of the pancreatic duct?
To carry pancreatic enzymes to the duodenum for digestion.
What is the measurement of the pancreatic duct/Winsung?
less than 2mm and tapers as it reaches the tail
The pancreatic duct/Winsung is what in most patient's via ultrasound?
NOT SEEN
Where is the location of the accessory duct/ Duct of Santorini?
secondary (accessory duct) that drains the upper anterior head
The Duct of Santorini enters...
the duodenum at the minor papilla about 2 cm proximal to the ampulla of Vater
What is the Sphinicter of Oddi and where located?
Muscle within the ampulla of Vater
What is function of the Sphincter of Oddi?
The muscle relaxes to allow pancreatic juices and bile to enter the duodenum.
What is digestive and hormonal glands of the pancreas?
Digestive (Exocrine Gland)
Hormonal (Endocrine Gland)
What is the primary function of the exocrine gland?
to produce pancreatic juice which enters duodenum together with bile
What is the primary function of endocrine gland?
to produce the hormone insulin
The exocrine gland performed by the acini cells of the pancreas produces how much pancreatic juice per day?
2 liters
Where does the pancreatic duct enter the duodenum?
through the duct of Wirsung
What are the enzymes of the pancreatic juice that aid in digestion?
1. Lipase = fats

2. Carboxpeptidase, Trypsin, and Chymotrypain = proteins

3. Nucleases =nucleic acids

4. Amylase = carbohydrates
The endocrine gland function is located....
in the islets of Langerhans in the pancreas
What are the specialized cells within the islets of Langerhans?
1. Alpha Cells
2. Beta Cells
3. Delta Cells
Alpha Cell function is to
Hormone Glucagon = Glycogen to Glucose
Beta Cell function is to
Hormone Insulin = Glucose to Glycogen
Delta Cell function is to
Hormone Somatostatin = Alpha and Beta inhibitor

DELTA SERVES AS THE CHECKS AND BALANCE OF THE Enzymes
Exocrine function comes from what part of the pancreas?
HEAD
Endocrine function comes from what part of the pancreas?
BODY and TAIL
What are the three laboratory test and which are the primary two test?
Amylase, Lipase, and Glucose

The two main are Amylase and Lipase
What does twice the normal levels of Amylase suggest?
Acute Pancreatitis
What happens to Amylase and Lipase in the rate the levels rise and which one stays elevated the longest?
both Amylase and Lipase rise at the same rate, but Lipase concentration persists for a long period
What happens with increased levels of Glucose?
Severe diabetes, Chronic liver disease, and overactivity of several of the endocrine glands
What does a patient need to do in order to help visualize the pancreas?
Be NPO or fast for 6-8 hours
Since eating does not affect the pancreas while scanning then why must a patient be NPO for 6-8 hours?
To eliminate the accumulation of gas from the stomach and duodenum, because gas hinders the view of the pancreas while scanning.
How is the pancreas related to the liver in appearance?
the pancreas is equal to or slightly more echogenic than the liver
Where is the main duct often identified and what are it's measurements?
Body of the Pancreas and it measures less than 2 mm
Congenital anomalies of the pancreas are...
RARE
Congenital anomalies include:
1. Ectopic pancreatic tissue
2. Annular pancreas
3. Fibrocystic disease of the pancreas
Which of the congential anomalies is the most common?
ECTOPIC PANCREATIC TISSUE
Where can Ectopic Pancreatic Tissue end up?
Various places of the GI Tract
What are the places in the GI tract can ectopic pancreatic tissue end up?
Stomach
Duodenum
Small and Large Bowel
Is ectopic pancreatic tissue in large or small amounts when found?
generally small
Annular pancreas is or is not common?
not common
Where does the second portion of the duodenum surround?
head of the pancreas
Annular pancreas is more common in which sex?
Males
What may be annular pancreas associated with?
Complete or Partial attresia of the duodenum
Fibrocystic disease of the pancreas is a ___________________.
Hereditary disorder of the exocrine gland
Fibrocystic disease is more likely to be seen in_________ and __________.
children and young adults
Fibrocystic disease cysts are of what size?
very small
What occurs in fibrocystic disease?
Normal tissue is replaced by fibrous tissue
What happens to the pancreatic secreations with Fibrocystic disease?
it is slowly lost
What is acute pancreatitis?
Inflammation of the pancreas
What is the most common cause of pancreaitis in the US?
Bilitary Tract Disease
Gallstones are present in ______of the patients with acute pancreatitis.
40-60%
What is the second most common cause of pancreatitis?
Alcohol abuse
What are the other causes acute pancreatitis?
Trauma
Inflammation from adjacent peptic ulcer
Abdominal infections
Drugs
What are the clinical findings of acute pancreatitis?
Acute Edematous (swollen) pancreatitis often resolves sponaneously

Moderate to severe tenderness in the epigastrium radiating to the back

RUQ pain especially following large meals with alcohol intake
What are the lab values of acute pancreatitis?
Serum Amylase increase within 24 hours

Serum Lipase increases within 72-94 hours

Leukocytosis

Fever
What is the sonographic appearance of acute pancreatitis?
Normal size or focal to diffuse enlargement

The echogenically varies depending on he severity but frequently is hypoechoic

Pancreatic duct may be enlarged

Borders are usually regular, but may be ill-defined

40-60% have gallstones

Pseudocysts
What usually causes chronic pancreatitis?
Repeated, persistent or prolonged subacute attacks of pancreatitis
What causes parenchymal destruction in chronic pancreatitis and what does it heal into?
repeated attacks of acute pancreatitis and the parenchymal destruction heals into fibrosis
What are the clinical findings of Chronic Pancreatitis?
non-specific

Patient may present with chronic epigastric and RUQ pain that radiates to the back and is aggravated by ingestion of alcohol of fatty food
What are the lab values of chronic pancreatitis?
Increase Amylase

Increased Lipase
What is the sonographic characteristics of chronic pancreatitis?
1. gland is usually smaller

2. irregular borders

3. dilated pancreatic duct

4. diffuse echogenicity

5. Echotexture may be heterogeneous because of fibrosis or calcifications

6. May have pseudocyst
What is the most severe form of pancreatitis?
Hemorrhagic
Where does hemorrhagic pancreatitis come from?
Rapid progression of acute pancreatitis
Describe hemorrhagic pancreatitis.
There is diffused enzymatic destruction of the pancreatic substance caused by a sudden escape of active pancreatic enzymes into glands tissue
The enzymes from Hemorrhagic pancreatitis cause....
focal (fluid) areas of necrosis in and around the pancreas which leads to rupture of pancreatic vessels and hemorrhage
What are the clinical findings of Hemorrhagic Pancreatits?
1. Intense and severe pain radiating to the neck

2. Discoloration of the flanks
In hemorrhagic pancreatitis discoloration of the flanks is called?
Grey Tumor's Sign
What are the lab values of Hemorrhagic Pancreatitis?
1. Elevated amylase

2. Elevated lipase

3. Elevated WBC's

4. Decreased hematocrit

5. Decrease serum calcium levels
What are the sonographic appearance of Hemorrhagic Pancreatitis?
1. Specific findings depends on the age of the hemorrhage

2. Well-defined homogenous mass in the area of the pancreas
What are pancreatic true cysts?
Microscopic sacs that may be congenital or acquired
Congenital pancreatic true cyst are the result of...
Abnormal development of he pancreatic duct
Acquired pancreatic true cysts are ...
retention cyst, parasitic cyst, or neoplastic cyst
What do true cysts walls contain?
epithelial lining
True cyst may contain...
pancreatic enzymes or be found to be continues with pancreatic duct
Pancreatic Pseudocyst's are...
Always acquired and may be caused by trauma to the gland or acute or chronic pancreatitis

Collection of inflammatory, necrotic tissue, pancreatic secretions and blood
Pancreatic Pseudocyst have______ ______ that surrounds a ___________ of ________ __________ and __________ ________.
fibrous lining
collection
pancreatic juice
necrotic debris
Pancreatic Pseudocyst are the results from....
rupture of the pancreatic duct secondary to pancreatitis with leakage or pancreatic juices and into the surrounding tissue
What is the most common location of a pancreatic pseudocyst?
in the lesser sac anterior to the pancreas and posterior to the pancreas and posterior to the stomach
Are pancreatic pseudocyst always spherical?
No, because they take on the contour of the available space around them
What are the clinical findings of pancreatic pseudocyst?
They usually occur following pancreatitis so the patient may have a history of pancreatits

Abdominal pain
Fever
Nausea/Vomiting
May have a palpable mass
What are the lab values of pancreatic pseudocyst?
Presistently elevated amylase
What is the sonographic appearance of pancreatic pseudocysts?
Well defined mass usually in the are of the pancreas.

Increased through transmission.

Variable in size (round and oval)

May have debris at the bottom
Islets Tumor
There are several types and can be functional or non-functional
Islet Tumors maybe
Benign adenomas or malignant tumors
Tumors occur mostly in the _____ and____of the pancreas but the greatest concentration are in the _______ of______
BODY
TAIL
ISLETS of LANGERHANS
Non-functioning islet tumors comprise ____of all islet cell tumors with ___being malignant.
1/3

92% are malignant
What are the characteristics of Islet Cell Tumors?
Small size makes them difficult to image.

Can be singular or multiple

Occur in the body and tail

Hyperechoic
What is the most common Islet Cell Tumor?
Insulinoma
Cystadenocarcinoma are....
uncommon slow growing tumor
Cystadenocarcinomas arise from...
the duct as cystic neoplasm
Cystadenocarcinoma has a significant potential of being ______
Malignant
What sex does cystadenocarcinoma occur more in?
Middle Aged Females
Cystadenocarcinoma metastases most commonly in the ______and ______
lymph nodes

liver
What are the clinical findings of Cystadenocarcinoma?
Epigastric pain
Pancreatic mass
Weightloss
What are the lab values of Cystadenocarcinoma?
Elevated Amylase
Elevated Bilirubin
Elevated Alk Phos
What is the sonographic characteristics of Cystadenocarcinoma?
Irregular lobulated cystic tumor

Thick walls
What is the most common primary neoplasm of the pancreas?
Adenocarcinoma
Majority of pancreatic malignancies occur where?
Pancreatic Head
Adenocarcinomas are ________ and involves the ________ portion of the gland.
fatal

exocrine gland
Adenocarcinomas are more common in what sex?
Males ages 60 to 80 years of age
Adenocarcinomas spread what organ at the time of initial presentation?
Liver
85% of patients
What site or part of the pancreas is effected and at what percent?
Pancreatic Head
60-70%
What are the clinical findings of Adenocarcinomas?
Painless Jaundice-Courvoiser Law Sign
Weight loss
Abdominal Pain
Palpable Mass
Onset of Diabetes
Pain radiating to the back
Nausea/Vomiting
What are the lab values of Adenocarcinomas?
Elevated Amylase
Elevated Lipase
Elevated Bilirubin
What is the clinical finding is commonly associated with Pancreatic Adenocarcinomas?
New On-Set of Diabetes
What is the sonographic characteristics of Adenocarcinoma?
Usually presents as a focal or contour deformity. (ie changes shape)

Pancreatic mass is frequently hypechoic and has irregular and ill-defined margins

Occasionally it may appear as diffused enlargement of the pancreas

Distal pancreatic duct may be dilated

CBD and intrahepatic ducts may be dilated

GB may be dilated and filled with sludge (Courvoisier's Law)
If adenocarcinoma is suspected the sonographer should look for what?
Metastic spread into the liver, paraortic nods, and portal venous system