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170 Cards in this Set

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Most important predictor of outcome with acetaminophen toxicity is:
4 hour post ingestion level. 150 or greater --> hepatic toxicity. 300 or greater --> severe liver damage
When should you give n-acetylcysteine?
When you know the 4 hour level is >150.
Toxidrome: tachycardia, nausea, vomiting htn, belly pain, diaphoresis, anorexia, tremulous, mydriasis, tachypnea, fever, delirium, psychosis
amphetamines
Toxidrome: mydriasis, absent sweating, ileus, tachycardia, delirium, disoriented, ataxia, halucinate, psychosis, seizure, coma, resp failure, urinary retention, hyperpyrexia,
anticholinergic
Toxidrome: salivation, lacrimation, emesis, bronchorrea, urination, diarrhea, cramping, seizures, miosis, bradycardia, muscle weakness
cholinergic (organophosphates)
Toxidrome: lethargy, coma, seizures, hypotension, prolonged qrs
cyclic antidepressants
Toxidrome: nausea, hematemesis, shock, hypotension, coma, hyperpyrexia, metaboic acidosis, coma, hepatitis,coma
iron
Toxidrome: rotary nystagmus, dissociative delusions, aggression, coma, seizures
phencyclidine
Toxidrome: tinnitus, tachypnea, confusion, fever, nausea, vomiting, metabolic acidosis
salicylates
Toxidrome: nausea, vomiting, tremors, tachycardia, arrhythmia, hypotension, confusion, seizures
theophylline
What substances do you NOT use activated charcoal for?
Cyanide, Alcohol, Lithium, Heavy Metals
What should you do with a coin in the proximal esophagus?
removed by endoscopy
Most important predictor of outcome with acetaminophen toxicity is:
4 hour post ingestion level. 150 or greater --> hepatic toxicity. 300 or greater --> severe liver damage
When do you give N-acetylcysteine without waiting for a tylenol level?
if they took more than 150 mg/kg
When should you give n-acetylcysteine?
When you know the 4 hour level is >150.
How do you treat a salicylate ingestion?
use sodium bicarb to alkalinize the urine. Address hypokalemia and hypoglycemia
Toxidrome: tachycardia, nausea, vomiting htn, belly pain, diaphoresis, anorexia, tremulous, mydriasis, tachypnea, fever, delirium, psychosis
amphetamines
How do you treat ibuprofen ingestion?
supportive care; check a tylenol level
Toxidrome: mydriasis, absent sweating, ileus, tachycardia, delirium, disoriented, ataxia, halucinate, psychosis, seizure, coma, resp failure, urinary retention, hyperpyrexia,
anticholinergic
Most common electrolyte abnormality with alcohol ingestion?
hypoglycemia
Toxidrome: pinpoint pupils, cyanosis, respiratory depression, bradycardia, hypotension, low temp
opiates
Toxidrome: salivation, lacrimation, emesis, bronchorrea, urination, diarrhea, cramping, seizures, miosis, bradycardia, muscle weakness
cholinergic (organophosphates)
Toxidrome: profuse sweating, tearing, abdominal pan, wheezing
organophosphates
Toxidrome: lethargy, coma, seizures, hypotension, prolonged qrs
cyclic antidepressants
How do you treat opiate toxicity?
narcan
Toxidrome: nausea, hematemesis, shock, hypotension, coma, hyperpyrexia, metaboic acidosis, coma, hepatitis,coma
iron
Toxidrome: rotary nystagmus, dissociative delusions, aggression, coma, seizures
phencyclidine
Toxidrome: violent, anasarca and mydriasis or asymmetric pupils
PCP
How do you treat organophosphate poisoning?
atropine
Toxidrome: tinnitus, tachypnea, confusion, fever, nausea, vomiting, metabolic acidosis
salicylates
Toxidrome: nausea, vomiting, tremors, tachycardia, arrhythmia, hypotension, confusion, seizures
theophylline
What is the mechanismo fo action of organophosphates?
interfere with acetylcholinesterase
Toxidrome: anorexia, headache, poor appetite, muscle weakness, visual disturbance, nausea, vomiting, fatigue
Digoxin toxicity
What substances do you NOT use activated charcoal for?
Cyanide, Alcohol, Lithium, Heavy Metals
Toxidrome: Anticholinergic symptoms with dysrhythmia
Tricyclic antidepressents
What should you do with a coin in the proximal esophagus?
removed by endoscopy
How do you treat TCA ingestion
alkalinize the urine; cardiac monitoring. - no cardiac meds.
When do you give N-acetylcysteine without waiting for a tylenol level?
if they took more than 150 mg/kg
Toxidrome: depressed sensoriu, bradycardia, hypotension, diaphoresis
beta blocker - cardiac monitoring needed.
How do you treat a salicylate ingestion?
use sodium bicarb to alkalinize the urine. Address hypokalemia and hypoglycemia
Toxidrome: hypoxemia, diffuse bilateral infiltrates, cough, tachypnea, history of choking/gagging
hydrocarbon
How do you treat ibuprofen ingestion?
supportive care; check a tylenol level
Most important predictor of outcome with acetaminophen toxicity is:
4 hour post ingestion level. 150 or greater --> hepatic toxicity. 300 or greater --> severe liver damage
When should you use a hyperbaric chamber for carbon monoxide poison? (when level is greater than. . . and 4 other things )
25%, pregnancy, acidsois, cardiac involvement, neuro involvement
Most common electrolyte abnormality with alcohol ingestion?
hypoglycemia
When should you give n-acetylcysteine?
When you know the 4 hour level is >150.
How do you distinguish cyanide poisoning from carbon monoxide?
Carbon monoxide responds to 100% O2 and improves.
Toxidrome: pinpoint pupils, cyanosis, respiratory depression, bradycardia, hypotension, low temp
opiates
Treatment for cyanide poisoning
sodium thiosulfate
Toxidrome: tachycardia, nausea, vomiting htn, belly pain, diaphoresis, anorexia, tremulous, mydriasis, tachypnea, fever, delirium, psychosis
amphetamines
Toxidrome: profuse sweating, tearing, abdominal pan, wheezing
organophosphates
Most important predictor of outcome with acetaminophen toxicity is:
4 hour post ingestion level. 150 or greater --> hepatic toxicity. 300 or greater --> severe liver damage
Toxidrome: looks drunk, large anon gap, oxalate crystals on UA
ethylene glycol
Toxidrome: mydriasis, absent sweating, ileus, tachycardia, delirium, disoriented, ataxia, halucinate, psychosis, seizure, coma, resp failure, urinary retention, hyperpyrexia,
anticholinergic
How do you treat opiate toxicity?
narcan
How do you treat iron ingestion?
Serum iron level 3-5 hours out; >500, use deferoxamine and gastric lavage
Toxidrome: violent, anasarca and mydriasis or asymmetric pupils
PCP
Toxidrome: salivation, lacrimation, emesis, bronchorrea, urination, diarrhea, cramping, seizures, miosis, bradycardia, muscle weakness
cholinergic (organophosphates)
Toxidrome: lethargy, coma, seizures, hypotension, prolonged qrs
cyclic antidepressants
How do you treat organophosphate poisoning?
atropine
How do you treat methemoglobinemia
methylene blue
When should you give n-acetylcysteine?
When you know the 4 hour level is >150.
Toxidrome: nausea, hematemesis, shock, hypotension, coma, hyperpyrexia, metaboic acidosis, coma, hepatitis,coma
iron
What meds put you at risk for methemoglobenemia
dapsone, sulfa, nitrates, teething baby (lidocaine), rasburicase, muscle relaxing gels
What is the mechanismo fo action of organophosphates?
interfere with acetylcholinesterase
Toxidrome: tachycardia, nausea, vomiting htn, belly pain, diaphoresis, anorexia, tremulous, mydriasis, tachypnea, fever, delirium, psychosis
amphetamines
Toxidrome: rotary nystagmus, dissociative delusions, aggression, coma, seizures
phencyclidine
Toxidrome: anorexia, headache, poor appetite, muscle weakness, visual disturbance, nausea, vomiting, fatigue
Digoxin toxicity
Toxidrome: Anticholinergic symptoms with dysrhythmia
Tricyclic antidepressents
How do you treat TCA ingestion
alkalinize the urine; cardiac monitoring. - no cardiac meds.
Toxidrome: tinnitus, tachypnea, confusion, fever, nausea, vomiting, metabolic acidosis
salicylates
Toxidrome: mydriasis, absent sweating, ileus, tachycardia, delirium, disoriented, ataxia, halucinate, psychosis, seizure, coma, resp failure, urinary retention, hyperpyrexia,
anticholinergic
Toxidrome: salivation, lacrimation, emesis, bronchorrea, urination, diarrhea, cramping, seizures, miosis, bradycardia, muscle weakness
cholinergic (organophosphates)
Toxidrome: depressed sensoriu, bradycardia, hypotension, diaphoresis
beta blocker - cardiac monitoring needed.
Toxidrome: nausea, vomiting, tremors, tachycardia, arrhythmia, hypotension, confusion, seizures
theophylline
Toxidrome: hypoxemia, diffuse bilateral infiltrates, cough, tachypnea, history of choking/gagging
hydrocarbon
When should you use a hyperbaric chamber for carbon monoxide poison? (when level is greater than. . . and 4 other things )
25%, pregnancy, acidsois, cardiac involvement, neuro involvement
Toxidrome: lethargy, coma, seizures, hypotension, prolonged qrs
cyclic antidepressants
What substances do you NOT use activated charcoal for?
Cyanide, Alcohol, Lithium, Heavy Metals
Toxidrome: nausea, hematemesis, shock, hypotension, coma, hyperpyrexia, metaboic acidosis, coma, hepatitis,coma
iron
What should you do with a coin in the proximal esophagus?
removed by endoscopy
How do you distinguish cyanide poisoning from carbon monoxide?
Carbon monoxide responds to 100% O2 and improves.
Toxidrome: rotary nystagmus, dissociative delusions, aggression, coma, seizures
phencyclidine
When do you give N-acetylcysteine without waiting for a tylenol level?
if they took more than 150 mg/kg
Treatment for cyanide poisoning
sodium thiosulfate
Toxidrome: looks drunk, large anon gap, oxalate crystals on UA
ethylene glycol
How do you treat a salicylate ingestion?
use sodium bicarb to alkalinize the urine. Address hypokalemia and hypoglycemia
How do you treat iron ingestion?
Serum iron level 3-5 hours out; >500, use deferoxamine and gastric lavage
How do you treat ibuprofen ingestion?
supportive care; check a tylenol level
Toxidrome: tinnitus, tachypnea, confusion, fever, nausea, vomiting, metabolic acidosis
salicylates
How do you treat methemoglobinemia
methylene blue
Most common electrolyte abnormality with alcohol ingestion?
hypoglycemia
Toxidrome: nausea, vomiting, tremors, tachycardia, arrhythmia, hypotension, confusion, seizures
theophylline
What substances do you NOT use activated charcoal for?
Cyanide, Alcohol, Lithium, Heavy Metals
Toxidrome: pinpoint pupils, cyanosis, respiratory depression, bradycardia, hypotension, low temp
opiates
What meds put you at risk for methemoglobenemia
dapsone, sulfa, nitrates, teething baby (lidocaine), rasburicase, muscle relaxing gels
What should you do with a coin in the proximal esophagus?
removed by endoscopy
Toxidrome: profuse sweating, tearing, abdominal pan, wheezing
organophosphates
When do you give N-acetylcysteine without waiting for a tylenol level?
if they took more than 150 mg/kg
How do you treat opiate toxicity?
narcan
How do you treat a salicylate ingestion?
use sodium bicarb to alkalinize the urine. Address hypokalemia and hypoglycemia
Toxidrome: violent, anasarca and mydriasis or asymmetric pupils
PCP
How do you treat ibuprofen ingestion?
supportive care; check a tylenol level
How do you treat organophosphate poisoning?
atropine
What is the mechanismo fo action of organophosphates?
interfere with acetylcholinesterase
Most common electrolyte abnormality with alcohol ingestion?
hypoglycemia
Toxidrome: pinpoint pupils, cyanosis, respiratory depression, bradycardia, hypotension, low temp
opiates
Toxidrome: anorexia, headache, poor appetite, muscle weakness, visual disturbance, nausea, vomiting, fatigue
Digoxin toxicity
Toxidrome: profuse sweating, tearing, abdominal pan, wheezing
organophosphates
Toxidrome: Anticholinergic symptoms with dysrhythmia
Tricyclic antidepressents
How do you treat TCA ingestion
alkalinize the urine; cardiac monitoring. - no cardiac meds.
How do you treat opiate toxicity?
narcan
Toxidrome: depressed sensoriu, bradycardia, hypotension, diaphoresis
beta blocker - cardiac monitoring needed.
Toxidrome: violent, anasarca and mydriasis or asymmetric pupils
PCP
Toxidrome: hypoxemia, diffuse bilateral infiltrates, cough, tachypnea, history of choking/gagging
hydrocarbon
How do you treat organophosphate poisoning?
atropine
When should you use a hyperbaric chamber for carbon monoxide poison? (when level is greater than. . . and 4 other things )
25%, pregnancy, acidsois, cardiac involvement, neuro involvement
What is the mechanismo fo action of organophosphates?
interfere with acetylcholinesterase
Most important predictor of outcome with acetaminophen toxicity is:
4 hour post ingestion level. 150 or greater --> hepatic toxicity. 300 or greater --> severe liver damage
How do you distinguish cyanide poisoning from carbon monoxide?
Carbon monoxide responds to 100% O2 and improves.
Toxidrome: anorexia, headache, poor appetite, muscle weakness, visual disturbance, nausea, vomiting, fatigue
Digoxin toxicity
When should you give n-acetylcysteine?
When you know the 4 hour level is >150.
Treatment for cyanide poisoning
sodium thiosulfate
Toxidrome: Anticholinergic symptoms with dysrhythmia
Tricyclic antidepressents
Toxidrome: tachycardia, nausea, vomiting htn, belly pain, diaphoresis, anorexia, tremulous, mydriasis, tachypnea, fever, delirium, psychosis
amphetamines
Toxidrome: looks drunk, large anon gap, oxalate crystals on UA
ethylene glycol
How do you treat TCA ingestion
alkalinize the urine; cardiac monitoring. - no cardiac meds.
Toxidrome: mydriasis, absent sweating, ileus, tachycardia, delirium, disoriented, ataxia, halucinate, psychosis, seizure, coma, resp failure, urinary retention, hyperpyrexia,
anticholinergic
How do you treat iron ingestion?
Serum iron level 3-5 hours out; >500, use deferoxamine and gastric lavage
Toxidrome: depressed sensoriu, bradycardia, hypotension, diaphoresis
beta blocker - cardiac monitoring needed.
Toxidrome: salivation, lacrimation, emesis, bronchorrea, urination, diarrhea, cramping, seizures, miosis, bradycardia, muscle weakness
cholinergic (organophosphates)
How do you treat methemoglobinemia
methylene blue
Toxidrome: hypoxemia, diffuse bilateral infiltrates, cough, tachypnea, history of choking/gagging
hydrocarbon
Toxidrome: lethargy, coma, seizures, hypotension, prolonged qrs
cyclic antidepressants
Toxidrome: nausea, hematemesis, shock, hypotension, coma, hyperpyrexia, metaboic acidosis, coma, hepatitis,coma
iron
When should you use a hyperbaric chamber for carbon monoxide poison? (when level is greater than. . . and 4 other things )
25%, pregnancy, acidsois, cardiac involvement, neuro involvement
What meds put you at risk for methemoglobenemia
dapsone, sulfa, nitrates, teething baby (lidocaine), rasburicase, muscle relaxing gels
How do you distinguish cyanide poisoning from carbon monoxide?
Carbon monoxide responds to 100% O2 and improves.
Toxidrome: rotary nystagmus, dissociative delusions, aggression, coma, seizures
phencyclidine
Toxidrome: tinnitus, tachypnea, confusion, fever, nausea, vomiting, metabolic acidosis
salicylates
Treatment for cyanide poisoning
sodium thiosulfate
Toxidrome: nausea, vomiting, tremors, tachycardia, arrhythmia, hypotension, confusion, seizures
theophylline
Toxidrome: looks drunk, large anon gap, oxalate crystals on UA
ethylene glycol
What substances do you NOT use activated charcoal for?
Cyanide, Alcohol, Lithium, Heavy Metals
How do you treat iron ingestion?
Serum iron level 3-5 hours out; >500, use deferoxamine and gastric lavage
How do you treat methemoglobinemia
methylene blue
What should you do with a coin in the proximal esophagus?
removed by endoscopy
When do you give N-acetylcysteine without waiting for a tylenol level?
if they took more than 150 mg/kg
What meds put you at risk for methemoglobenemia
dapsone, sulfa, nitrates, teething baby (lidocaine), rasburicase, muscle relaxing gels
How do you treat a salicylate ingestion?
use sodium bicarb to alkalinize the urine. Address hypokalemia and hypoglycemia
How do you treat ibuprofen ingestion?
supportive care; check a tylenol level
Most common electrolyte abnormality with alcohol ingestion?
hypoglycemia
Toxidrome: pinpoint pupils, cyanosis, respiratory depression, bradycardia, hypotension, low temp
opiates
Toxidrome: profuse sweating, tearing, abdominal pan, wheezing
organophosphates
How do you treat opiate toxicity?
narcan
Toxidrome: violent, anasarca and mydriasis or asymmetric pupils
PCP
How do you treat organophosphate poisoning?
atropine
What is the mechanismo fo action of organophosphates?
interfere with acetylcholinesterase
Toxidrome: anorexia, headache, poor appetite, muscle weakness, visual disturbance, nausea, vomiting, fatigue
Digoxin toxicity
Toxidrome: Anticholinergic symptoms with dysrhythmia
Tricyclic antidepressents
How do you treat TCA ingestion
alkalinize the urine; cardiac monitoring. - no cardiac meds.
Toxidrome: depressed sensoriu, bradycardia, hypotension, diaphoresis
beta blocker - cardiac monitoring needed.
Toxidrome: hypoxemia, diffuse bilateral infiltrates, cough, tachypnea, history of choking/gagging
hydrocarbon
When should you use a hyperbaric chamber for carbon monoxide poison? (when level is greater than. . . and 4 other things )
25%, pregnancy, acidsois, cardiac involvement, neuro involvement
How do you distinguish cyanide poisoning from carbon monoxide?
Carbon monoxide responds to 100% O2 and improves.
Treatment for cyanide poisoning
sodium thiosulfate
Toxidrome: looks drunk, large anon gap, oxalate crystals on UA
ethylene glycol
How do you treat iron ingestion?
Serum iron level 3-5 hours out; >500, use deferoxamine and gastric lavage
How do you treat methemoglobinemia
methylene blue
What meds put you at risk for methemoglobenemia
dapsone, sulfa, nitrates, teething baby (lidocaine), rasburicase, muscle relaxing gels